Fezf2

Functionⁱ

GO - Molecular functionⁱ

chromatin binding Source: Ensembl
RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Source: Ensembl
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Source: Ensembl

Complete GO annotation...

GO - Biological processⁱ

axonal fasciculation Source: Ensembl
axon guidance Source: Ensembl
cerebral cortex GABAergic interneuron migration Source: Ensembl
commitment of neuronal cell to specific neuron type in forebrain Source: Ensembl
dendrite development Source: Ensembl
dentate gyrus development Source: Ensembl
forebrain anterior/posterior pattern specification Source: Ensembl
locomotory behavior Source: Ensembl
negative regulation of cell proliferation Source: Ensembl
negative regulation of neuron differentiation Source: Ensembl
neuron fate determination Source: Ensembl
positive regulation of neuron differentiation Source: Ensembl
regulation of axon guidance Source: Ensembl

Complete GO annotation...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Fez family zinc finger 2Imported Submitted name: Zinc finger protein 312 (Predicted)Imported
Gene namesⁱ	Name:Fezf2Imported Synonyms:Zfp312_predictedImported ORF Names:rCG_42138Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 15

Organism-specific databases

Rat genome database More...RGDⁱ	1311068. Fezf2.

RGDⁱ

1311068. Fezf2.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000009206.

Bgeeⁱ

ENSRNOG00000009206.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000012452.

STRINGⁱ

10116.ENSRNOP00000012452.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	272 – 299	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	300 – 327	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	328 – 355	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	356 – 383	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	384 – 411	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	412 – 440	C2H2-typeInterPro annotationAdd BLAST	29

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00740000115096.
HOGENOMⁱ	HOG000013052.
HOVERGENⁱ	HBG098441.
OMAⁱ	KPQVIHQ.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ISJ.
TreeFamⁱ	TF316780.

Family and domain databases

Gene3Dⁱ	3.30.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR013087. Znf_C2H2_type. IPR013083. Znf_RING/FYVE/PHD.
SMARTⁱ	View protein in SMART SM00355. ZnF_C2H2. 6 hits.
SUPFAMⁱ	SSF57667. SSF57667. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

B4F7C0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MASSASLETM VPPACPRAGA SPATSKTLAF SIERIMAKTS EPRAPFEPRP 
        60         70         80         90        100
AALEADSSQS KKLLNLCSPL PCMIPLQPLG YEVPSKTLLS YSEFWKSSLR 
       110        120        130        140        150
AGGGGGGGSG GGGPVCGASG LCKTNCGVCC KAELGLAPSA LPAGRVIKPQ 
       160        170        180        190        200
VINQAVGLPA SGSLYYFNYL DSTTYPPSEL LGGHLFPSGL LNAQAPTSLA 
       210        220        230        240        250
AHPKLFLLEN AKLASLTADK FPHPASYPHK ERLHAPLEQV LKENSALTAE 
       260        270        280        290        300
RGGVKSHSKL PGGSTDSKPK NFTCEVCGKV FNAHYNLTRH MPVHTGARPF 
       310        320        330        340        350
VCKVCGKGFR QASTLCRHKI IHTQEKPHKC NQCGKAFNRS STLNTHIRIH 
       360        370        380        390        400
AGYKPFVCEF CGKGFHQKGN YKNHKLTHSG EKQYKCTICN KAFHQVYNLT 
       410        420        430        440        450
FHMHTHNDKK PFTCATCGKG FCRNFDLKKH VRKLHDSVGP TATPSAKGLA 

RTVQS

Length:455

Mass (Da):48,919

Last modified:September 23, 2008 - v1

Checksum:ⁱ149A6B2AB64DEF55

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07017145 Genomic DNA. No translation available. BC168214 mRNA. Translation: AAI68214.1. CH474010 Genomic DNA. Translation: EDL94136.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001100721.1. NM_001107251.1. XP_017455138.1. XM_017599649.1. XP_017455139.1. XM_017599650.1. XP_017455140.1. XM_017599651.1.
UniGeneⁱ	Rn.69050.

Genome annotation databases

Ensemblⁱ	ENSRNOT00000012452; ENSRNOP00000012452; ENSRNOG00000009206.
GeneIDⁱ	305719.
KEGGⁱ	rno:305719.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07017145 Genomic DNA. No translation available. BC168214 mRNA. Translation: AAI68214.1. CH474010 Genomic DNA. Translation: EDL94136.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001100721.1. NM_001107251.1. XP_017455138.1. XM_017599649.1. XP_017455139.1. XM_017599650.1. XP_017455140.1. XM_017599651.1.
UniGeneⁱ	Rn.69050.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000012452.

STRINGⁱ

10116.ENSRNOP00000012452.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000012452; ENSRNOP00000012452; ENSRNOG00000009206.
GeneIDⁱ	305719.
KEGGⁱ	rno:305719.

Organism-specific databases

CTDⁱ	55079.
Rat genome database More...RGDⁱ	1311068. Fezf2.

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00740000115096.
HOGENOMⁱ	HOG000013052.
HOVERGENⁱ	HBG098441.
OMAⁱ	KPQVIHQ.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ISJ.
TreeFamⁱ	TF316780.

Gene expression databases

Bgeeⁱ	ENSRNOG00000009206.

Bgeeⁱ

ENSRNOG00000009206.

Family and domain databases

Gene3Dⁱ	3.30.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR013087. Znf_C2H2_type. IPR013083. Znf_RING/FYVE/PHD.
SMARTⁱ	View protein in SMART SM00355. ZnF_C2H2. 6 hits.
SUPFAMⁱ	SSF57667. SSF57667. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B4F7C0_RAT
Accessionⁱ	B4F7C0Primary (citable) accession number: B4F7C0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 23, 2008
	Last sequence update:	September 23, 2008
	Last modified:	June 7, 2017
	This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - B4F7C0 (B4F7C0_RAT)

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Fez family zinc finger 2

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B4F7C0 (B4F7C0_RAT)

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Fez family zinc finger 2

Fezf2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ