UniProtKB - B4F7C0 (B4F7C0_RAT)
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Protein
Submitted name:
Fez family zinc finger 2
Gene
Fezf2
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: RGD
- RNA polymerase II proximal promoter sequence-specific DNA binding Source: RGD
- sequence-specific DNA binding Source: RGD
- transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
- transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
- transcription regulatory region DNA binding Source: RGD
GO - Biological processi
- axonal fasciculation Source: RGD
- axon guidance Source: RGD
- cell dedifferentiation Source: RGD
- cerebral cortex GABAergic interneuron migration Source: RGD
- cerebral cortex neuron differentiation Source: RGD
- commitment of neuronal cell to specific neuron type in forebrain Source: RGD
- dendrite development Source: RGD
- dentate gyrus development Source: RGD
- forebrain anterior/posterior pattern specification Source: RGD
- forebrain development Source: RGD
- locomotory behavior Source: RGD
- negative regulation of cell proliferation Source: RGD
- negative regulation of neuron differentiation Source: RGD
- negative regulation of transcription by RNA polymerase II Source: RGD
- neuron fate determination Source: RGD
- positive regulation of neuron differentiation Source: RGD
- positive regulation of transcription, DNA-templated Source: RGD
- regulation of axon guidance Source: RGD
- regulation of neurogenesis Source: RGD
- telencephalon development Source: RGD
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Fez family zinc finger 2ImportedSubmitted name: Zinc finger protein 312 (Predicted)Imported |
Gene namesi | ORF Names:rCG_42138Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1311068. Fezf2. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 272 – 299 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 300 – 327 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 328 – 355 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 356 – 383 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 384 – 411 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 412 – 440 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721. Eukaryota. COG5048. LUCA. |
GeneTreei | ENSGT00740000115096. |
HOGENOMi | HOG000013052. |
HOVERGENi | HBG098441. |
OMAi | KPQVIHQ. |
OrthoDBi | EOG091G0ISJ. |
TreeFami | TF316780. |
Family and domain databases
InterProi | View protein in InterPro IPR036236. Znf_C2H2_sf. IPR013087. Znf_C2H2_type. |
SMARTi | View protein in SMART SM00355. ZnF_C2H2. 6 hits. |
SUPFAMi | SSF57667. SSF57667. 3 hits. |
PROSITEi | View protein in PROSITE PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 6 hits. |
i Sequence
Sequence statusi: Complete.
B4F7C0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASSASLETM VPPACPRAGA SPATSKTLAF SIERIMAKTS EPRAPFEPRP
60 70 80 90 100
AALEADSSQS KKLLNLCSPL PCMIPLQPLG YEVPSKTLLS YSEFWKSSLR
110 120 130 140 150
AGGGGGGGSG GGGPVCGASG LCKTNCGVCC KAELGLAPSA LPAGRVIKPQ
160 170 180 190 200
VINQAVGLPA SGSLYYFNYL DSTTYPPSEL LGGHLFPSGL LNAQAPTSLA
210 220 230 240 250
AHPKLFLLEN AKLASLTADK FPHPASYPHK ERLHAPLEQV LKENSALTAE
260 270 280 290 300
RGGVKSHSKL PGGSTDSKPK NFTCEVCGKV FNAHYNLTRH MPVHTGARPF
310 320 330 340 350
VCKVCGKGFR QASTLCRHKI IHTQEKPHKC NQCGKAFNRS STLNTHIRIH
360 370 380 390 400
AGYKPFVCEF CGKGFHQKGN YKNHKLTHSG EKQYKCTICN KAFHQVYNLT
410 420 430 440 450
FHMHTHNDKK PFTCATCGKG FCRNFDLKKH VRKLHDSVGP TATPSAKGLA
RTVQS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07017145 Genomic DNA. No translation available. BC168214 mRNA. Translation: AAI68214.1. CH474010 Genomic DNA. Translation: EDL94136.1. |
RefSeqi | NP_001100721.1. NM_001107251.1. XP_017455138.1. XM_017599649.1. XP_017455139.1. XM_017599650.1. XP_017455140.1. XM_017599651.1. |
UniGenei | Rn.69050. |
Genome annotation databases
Ensembli | ENSRNOT00000012452; ENSRNOP00000012452; ENSRNOG00000009206. |
GeneIDi | 305719. |
KEGGi | rno:305719. |
Similar proteinsi
Entry informationi
Entry namei | B4F7C0_RAT | |
Accessioni | B4F7C0Primary (citable) accession number: B4F7C0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 23, 2008 |
Last sequence update: | September 23, 2008 | |
Last modified: | March 28, 2018 | |
This is version 77 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |