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Protein

Dymeclin

Gene

Dym

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Necessary for correct organization of Golgi apparatus. Involved in bone development.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Dymeclin
Gene namesi
Name:Dym
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1309111 Dym

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00003650122 – 674DymeclinAdd BLAST673

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1

Post-translational modificationi

Myristoylated in vitro; myristoylation is not essential for protein targeting to Golgi compartment.By similarity

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

PaxDbiB4F766
PeptideAtlasiB4F766
PRIDEiB4F766

Expressioni

Gene expression databases

GenevisibleiB4F766 RN

Interactioni

Subunit structurei

Interacts with GOLM1 and PPIB.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000024950

Family & Domainsi

Sequence similaritiesi

Belongs to the dymeclin family.Curated

Phylogenomic databases

eggNOGiKOG2225 Eukaryota
ENOG410XP0J LUCA
HOGENOMiHOG000006864
HOVERGENiHBG057356
InParanoidiB4F766
PhylomeDBiB4F766
TreeFamiTF314870

Family and domain databases

InterProiView protein in InterPro
IPR019142 Dymeclin
PANTHERiPTHR12895 PTHR12895, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B4F766-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSNSSKISD LPKNEYLKRL SGPEAISEND PFWNQLFSFS FSAPTSSTEL
60 70 80 90 100
KLLEEATISV CKSLVENNPR TGNLAALTKV FLARTRELRL SAECQNHIFI
110 120 130 140 150
WQTHNALFII CCLLKVFICE MSEEELQLHF TYEEKLPGTY TLCVLLGSDS
160 170 180 190 200
EDLLEELLCS LIQLITDTPL LDITYEISVE AISAMIVFLS CQLFHKEVLR
210 220 230 240 250
QSISHKYLMQ GPCLPYTSKL VKTLLYNFIR QEKPPPPGTH VFPQQSDGGG
260 270 280 290 300
LLYGLASGVA TGLWTVFTLG GVGSKAASPE LTSPLANQSL LLLLVLVNLT
310 320 330 340 350
DAPDIPNPYR QAVTSFKNTQ DSSPFPSSVP HTFQINFNSL YTTLCEQQTS
360 370 380 390 400
DQATLLLYTL LHQNANVRTY MLARTDMENL VLPILEILYH VEERNSHHVY
410 420 430 440 450
MALIILLILT EDDGFNRSIH EVILKNITWY SERVLTEISL GSLLILVVIR
460 470 480 490 500
TIQYNMTRTR DKYLHTNCLA ALANMSAQFR SLHQYAAQRI ISLFSLLSKK
510 520 530 540 550
HNKVLEQATQ SLRGSLSSSD VPLPDYAQDL SVIEEVIRMM LEIINSCLTN
560 570 580 590 600
SLHHNPNLVY ALLYKRDLFE QFRTHPSFQD IMQNIDLVIS FFSSRLLQSG
610 620 630 640 650
AELSVERVLE IIKQGVVALP KDRLKKFPEL KFKYVEEEQP EEFFIPYVWS
660 670
LVYNSAVGLY WNPQDIQLFA MDSD
Length:674
Mass (Da):76,491
Last modified:September 23, 2008 - v1
Checksum:i85691C69FDD44278
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC168151 mRNA Translation: AAI68151.1
RefSeqiXP_017456369.1, XM_017600880.1
UniGeneiRn.59303

Genome annotation databases

GeneIDi291433

Similar proteinsi

Entry informationi

Entry nameiDYM_RAT
AccessioniPrimary (citable) accession number: B4F766
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health