Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4F6U4

- PRD10_XENTR

UniProt

B4F6U4 - PRD10_XENTR

Protein

PR domain zinc finger protein 10

Gene

prdm10

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May be involved in transcriptional regulation.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri395 – 41723C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri559 – 58123C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri589 – 61123C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri617 – 63923C2H2-type 4PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri645 – 66824C2H2-type 5PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri673 – 69523C2H2-type 6PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri701 – 72424C2H2-type 7PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri756 – 77924C2H2-type 8PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri801 – 82424C2H2-type 9PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri863 – 88624C2H2-type 10PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. methyltransferase activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, S-adenosyl-L-methionine, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PR domain zinc finger protein 10 (EC:2.1.1.-)
    Alternative name(s):
    PR domain-containing protein 10
    Gene namesi
    Name:prdm10
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
    ProteomesiUP000008143: Unplaced

    Organism-specific databases

    XenbaseiXB-GENE-985864. prdm10.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11731173PR domain zinc finger protein 10PRO_0000363966Add
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini248 – 366119SETPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi174 – 18411Poly-AspAdd
    BLAST
    Compositional biasi943 – 1058116Gln-richAdd
    BLAST
    Compositional biasi1157 – 11604Poly-Thr

    Domaini

    The SET domain is degenerated, suggesting that it has lost methyltransferase activity.

    Sequence similaritiesi

    Belongs to the class V-like SAM-binding methyltransferase superfamily.PROSITE-ProRule annotation
    Contains 10 C2H2-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 SET domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri395 – 41723C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri559 – 58123C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri589 – 61123C2H2-type 3PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri617 – 63923C2H2-type 4PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri645 – 66824C2H2-type 5PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri673 – 69523C2H2-type 6PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri701 – 72424C2H2-type 7PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri756 – 77924C2H2-type 8PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri801 – 82424C2H2-type 9PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri863 – 88624C2H2-type 10PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    HOVERGENiHBG053664.

    Family and domain databases

    Gene3Di3.30.160.60. 5 hits.
    InterProiIPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view]
    PfamiPF00096. zf-C2H2. 4 hits.
    [Graphical view]
    SMARTiSM00355. ZnF_C2H2. 10 hits.
    [Graphical view]
    PROSITEiPS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 10 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4F6U4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDTKEGSPHV WPTSVEHQSN TAQVHFVPDG GSVAQIVYSD DQDRAQQQVV     50
    YTADASSFTS VDASEHTLVY IHPVDGSQTL FTDQPQVAYV QQDATTQQVT 100
    VLLPAAQSMN AANLAVLSGV SESAQTMSLD PVSQINRASL TVHDHRLPPM 150
    EGADSSTTIN SLPSPNAHSD GKEDDDDDDD DDDDEEEEDD DGEDSDLDDW 200
    EAEPPRPFDP NDLWCEECNN AHPSVCPKHG ALHPIPNRPV LTRARASLPL 250
    VLYIDRFLGG VYSKRRIPKR TQFGPLEGPL VKKTELKDSY IHLKVALNSP 300
    VDSEGAFQED LWFELSEESL CNWMMFVRPA QNHLEQNLVA YQYGQHIYFT 350
    TIKNIEPKQE LKVWYAASYA EFVNEKIHDI TQEERKVLRE QEKNWPCYEC 400
    NRRFMSSEQL QQHLNSHDEK LDFISRTKPR GRTRTRRKFG PGRRPGRPPK 450
    FLRFDISSEN REKIDLGTQD LLQFHNKGPH FEDCGHSTLN GLEQSELTLG 500
    TSTQGTPNQQ QATQLLPPNE ISTPVATTSI LTAEDMRRAK RIRNAALQHL 550
    FIRKSFRPFK CLQCGKAFRE KEKLDQHLRF HGRDGNYPLT CDICNKGFIS 600
    TSSLENHMKF HLDQKTYSCI FCPESFDRLD LLKDHVVVHI IDGCFSCPTC 650
    KKRFTDFIQV KKHVRSFHSE KIYQCTECDK AFCRPDKLRL HMLRHSDRKD 700
    FLCSTCGKQF KRKDKLREHM QRMHNPEREA KKADRTGRAK AFKPRLASTD 750
    YESFMFKCRV CMMGFRRRGM LVNHLSKRHP EMKIDEVPEL TLPIIKPNRD 800
    YYCQYCEKVY KSASKRKAHI LKNHPGAELP PSIRKLRPAG PGEPDPMLST 850
    HTQLTGTIAT PPVCCPHCSK QYSSKTKMVQ HIRKKHPEFS LLPISVQAPV 900
    LGTAPAVLTA DGTSGETVVT TDLLTQAMTE LSQTLTTEYR TPQGDFQRIQ 950
    YIPVSQTTGG MQQPQHIQLQ VVQVAQAQSP NQSQHSTVDM GQLHESQGYM 1000
    QHAIQVQHIQ VAEPTSGTQS TPQVGGQALS PSSQEAEEVN PSQLQTPASQ 1050
    AQANSAVQHA YLPSGWNSFR GYPSEIQMMA LPQGQYVIAE AAVGTPVTPV 1100
    SSGQVKAVTQ THYVISEGQG VLDMKKSSSL AEEATPNPDH MEQPASNSSQ 1150
    TTQYIITTTT NMNGSSEVHI SKP 1173
    Length:1,173
    Mass (Da):132,140
    Last modified:September 23, 2008 - v1
    Checksum:i03B08ECC73CD1BE3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC168013 mRNA. Translation: AAI68013.1.
    RefSeqiNP_001135541.1. NM_001142069.1.
    UniGeneiStr.58567.

    Genome annotation databases

    GeneIDi100216084.
    KEGGixtr:100216084.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC168013 mRNA. Translation: AAI68013.1 .
    RefSeqi NP_001135541.1. NM_001142069.1.
    UniGenei Str.58567.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100216084.
    KEGGi xtr:100216084.

    Organism-specific databases

    CTDi 56980.
    Xenbasei XB-GENE-985864. prdm10.

    Phylogenomic databases

    HOVERGENi HBG053664.

    Family and domain databases

    Gene3Di 3.30.160.60. 5 hits.
    InterProi IPR001214. SET_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR013087. Znf_C2H2/integrase_DNA-bd.
    [Graphical view ]
    Pfami PF00096. zf-C2H2. 4 hits.
    [Graphical view ]
    SMARTi SM00355. ZnF_C2H2. 10 hits.
    [Graphical view ]
    PROSITEi PS50280. SET. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 10 hits.
    PS50157. ZINC_FINGER_C2H2_2. 10 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiPRD10_XENTR
    AccessioniPrimary (citable) accession number: B4F6U4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3