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B4F6U4

- PRD10_XENTR

UniProt

B4F6U4 - PRD10_XENTR

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Protein

PR domain zinc finger protein 10

Gene
prdm10
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri395 – 41723C2H2-type 1Add
BLAST
Zinc fingeri559 – 58123C2H2-type 2Add
BLAST
Zinc fingeri589 – 61123C2H2-type 3Add
BLAST
Zinc fingeri617 – 63923C2H2-type 4Add
BLAST
Zinc fingeri645 – 66824C2H2-type 5Add
BLAST
Zinc fingeri673 – 69523C2H2-type 6Add
BLAST
Zinc fingeri701 – 72424C2H2-type 7Add
BLAST
Zinc fingeri756 – 77924C2H2-type 8Add
BLAST
Zinc fingeri801 – 82424C2H2-type 9Add
BLAST
Zinc fingeri863 – 88624C2H2-type 10Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. methyltransferase activity Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, S-adenosyl-L-methionine, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
PR domain zinc finger protein 10 (EC:2.1.1.-)
Alternative name(s):
PR domain-containing protein 10
Gene namesi
Name:prdm10
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
ProteomesiUP000008143: Unplaced

Organism-specific databases

XenbaseiXB-GENE-985864. prdm10.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11731173PR domain zinc finger protein 10PRO_0000363966Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini248 – 366119SETAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi174 – 18411Poly-AspAdd
BLAST
Compositional biasi943 – 1058116Gln-richAdd
BLAST
Compositional biasi1157 – 11604Poly-Thr

Domaini

The SET domain is degenerated, suggesting that it has lost methyltransferase activity.

Sequence similaritiesi

Contains 10 C2H2-type zinc fingers.
Contains 1 SET domain.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG053664.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 10 hits.
[Graphical view]
PROSITEiPS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 10 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4F6U4-1 [UniParc]FASTAAdd to Basket

« Hide

MDTKEGSPHV WPTSVEHQSN TAQVHFVPDG GSVAQIVYSD DQDRAQQQVV     50
YTADASSFTS VDASEHTLVY IHPVDGSQTL FTDQPQVAYV QQDATTQQVT 100
VLLPAAQSMN AANLAVLSGV SESAQTMSLD PVSQINRASL TVHDHRLPPM 150
EGADSSTTIN SLPSPNAHSD GKEDDDDDDD DDDDEEEEDD DGEDSDLDDW 200
EAEPPRPFDP NDLWCEECNN AHPSVCPKHG ALHPIPNRPV LTRARASLPL 250
VLYIDRFLGG VYSKRRIPKR TQFGPLEGPL VKKTELKDSY IHLKVALNSP 300
VDSEGAFQED LWFELSEESL CNWMMFVRPA QNHLEQNLVA YQYGQHIYFT 350
TIKNIEPKQE LKVWYAASYA EFVNEKIHDI TQEERKVLRE QEKNWPCYEC 400
NRRFMSSEQL QQHLNSHDEK LDFISRTKPR GRTRTRRKFG PGRRPGRPPK 450
FLRFDISSEN REKIDLGTQD LLQFHNKGPH FEDCGHSTLN GLEQSELTLG 500
TSTQGTPNQQ QATQLLPPNE ISTPVATTSI LTAEDMRRAK RIRNAALQHL 550
FIRKSFRPFK CLQCGKAFRE KEKLDQHLRF HGRDGNYPLT CDICNKGFIS 600
TSSLENHMKF HLDQKTYSCI FCPESFDRLD LLKDHVVVHI IDGCFSCPTC 650
KKRFTDFIQV KKHVRSFHSE KIYQCTECDK AFCRPDKLRL HMLRHSDRKD 700
FLCSTCGKQF KRKDKLREHM QRMHNPEREA KKADRTGRAK AFKPRLASTD 750
YESFMFKCRV CMMGFRRRGM LVNHLSKRHP EMKIDEVPEL TLPIIKPNRD 800
YYCQYCEKVY KSASKRKAHI LKNHPGAELP PSIRKLRPAG PGEPDPMLST 850
HTQLTGTIAT PPVCCPHCSK QYSSKTKMVQ HIRKKHPEFS LLPISVQAPV 900
LGTAPAVLTA DGTSGETVVT TDLLTQAMTE LSQTLTTEYR TPQGDFQRIQ 950
YIPVSQTTGG MQQPQHIQLQ VVQVAQAQSP NQSQHSTVDM GQLHESQGYM 1000
QHAIQVQHIQ VAEPTSGTQS TPQVGGQALS PSSQEAEEVN PSQLQTPASQ 1050
AQANSAVQHA YLPSGWNSFR GYPSEIQMMA LPQGQYVIAE AAVGTPVTPV 1100
SSGQVKAVTQ THYVISEGQG VLDMKKSSSL AEEATPNPDH MEQPASNSSQ 1150
TTQYIITTTT NMNGSSEVHI SKP 1173
Length:1,173
Mass (Da):132,140
Last modified:September 23, 2008 - v1
Checksum:i03B08ECC73CD1BE3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC168013 mRNA. Translation: AAI68013.1.
RefSeqiNP_001135541.1. NM_001142069.1.
UniGeneiStr.58567.

Genome annotation databases

GeneIDi100216084.
KEGGixtr:100216084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC168013 mRNA. Translation: AAI68013.1 .
RefSeqi NP_001135541.1. NM_001142069.1.
UniGenei Str.58567.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100216084.
KEGGi xtr:100216084.

Organism-specific databases

CTDi 56980.
Xenbasei XB-GENE-985864. prdm10.

Phylogenomic databases

HOVERGENi HBG053664.

Family and domain databases

Gene3Di 3.30.160.60. 5 hits.
InterProi IPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
Pfami PF00096. zf-C2H2. 4 hits.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 10 hits.
[Graphical view ]
PROSITEi PS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 10 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiPRD10_XENTR
AccessioniPrimary (citable) accession number: B4F6U4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: September 23, 2008
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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