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B4F6U4 (PRD10_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PR domain zinc finger protein 10

EC=2.1.1.-
Alternative name(s):
PR domain-containing protein 10
Gene names
Name:prdm10
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length1173 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in transcriptional regulation By similarity.

Subcellular location

Nucleus By similarity.

Domain

The SET domain is degenerated, suggesting that it has lost methyltransferase activity.

Sequence similarities

Belongs to the class V-like SAM-binding methyltransferase superfamily.

Contains 10 C2H2-type zinc fingers.

Contains 1 SET domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11731173PR domain zinc finger protein 10
PRO_0000363966

Regions

Domain248 – 366119SET
Zinc finger395 – 41723C2H2-type 1
Zinc finger559 – 58123C2H2-type 2
Zinc finger589 – 61123C2H2-type 3
Zinc finger617 – 63923C2H2-type 4
Zinc finger645 – 66824C2H2-type 5
Zinc finger673 – 69523C2H2-type 6
Zinc finger701 – 72424C2H2-type 7
Zinc finger756 – 77924C2H2-type 8
Zinc finger801 – 82424C2H2-type 9
Zinc finger863 – 88624C2H2-type 10
Compositional bias174 – 18411Poly-Asp
Compositional bias943 – 1058116Gln-rich
Compositional bias1157 – 11604Poly-Thr

Sequences

Sequence LengthMass (Da)Tools
B4F6U4 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 03B08ECC73CD1BE3

FASTA1,173132,140
        10         20         30         40         50         60 
MDTKEGSPHV WPTSVEHQSN TAQVHFVPDG GSVAQIVYSD DQDRAQQQVV YTADASSFTS 

        70         80         90        100        110        120 
VDASEHTLVY IHPVDGSQTL FTDQPQVAYV QQDATTQQVT VLLPAAQSMN AANLAVLSGV 

       130        140        150        160        170        180 
SESAQTMSLD PVSQINRASL TVHDHRLPPM EGADSSTTIN SLPSPNAHSD GKEDDDDDDD 

       190        200        210        220        230        240 
DDDDEEEEDD DGEDSDLDDW EAEPPRPFDP NDLWCEECNN AHPSVCPKHG ALHPIPNRPV 

       250        260        270        280        290        300 
LTRARASLPL VLYIDRFLGG VYSKRRIPKR TQFGPLEGPL VKKTELKDSY IHLKVALNSP 

       310        320        330        340        350        360 
VDSEGAFQED LWFELSEESL CNWMMFVRPA QNHLEQNLVA YQYGQHIYFT TIKNIEPKQE 

       370        380        390        400        410        420 
LKVWYAASYA EFVNEKIHDI TQEERKVLRE QEKNWPCYEC NRRFMSSEQL QQHLNSHDEK 

       430        440        450        460        470        480 
LDFISRTKPR GRTRTRRKFG PGRRPGRPPK FLRFDISSEN REKIDLGTQD LLQFHNKGPH 

       490        500        510        520        530        540 
FEDCGHSTLN GLEQSELTLG TSTQGTPNQQ QATQLLPPNE ISTPVATTSI LTAEDMRRAK 

       550        560        570        580        590        600 
RIRNAALQHL FIRKSFRPFK CLQCGKAFRE KEKLDQHLRF HGRDGNYPLT CDICNKGFIS 

       610        620        630        640        650        660 
TSSLENHMKF HLDQKTYSCI FCPESFDRLD LLKDHVVVHI IDGCFSCPTC KKRFTDFIQV 

       670        680        690        700        710        720 
KKHVRSFHSE KIYQCTECDK AFCRPDKLRL HMLRHSDRKD FLCSTCGKQF KRKDKLREHM 

       730        740        750        760        770        780 
QRMHNPEREA KKADRTGRAK AFKPRLASTD YESFMFKCRV CMMGFRRRGM LVNHLSKRHP 

       790        800        810        820        830        840 
EMKIDEVPEL TLPIIKPNRD YYCQYCEKVY KSASKRKAHI LKNHPGAELP PSIRKLRPAG 

       850        860        870        880        890        900 
PGEPDPMLST HTQLTGTIAT PPVCCPHCSK QYSSKTKMVQ HIRKKHPEFS LLPISVQAPV 

       910        920        930        940        950        960 
LGTAPAVLTA DGTSGETVVT TDLLTQAMTE LSQTLTTEYR TPQGDFQRIQ YIPVSQTTGG 

       970        980        990       1000       1010       1020 
MQQPQHIQLQ VVQVAQAQSP NQSQHSTVDM GQLHESQGYM QHAIQVQHIQ VAEPTSGTQS 

      1030       1040       1050       1060       1070       1080 
TPQVGGQALS PSSQEAEEVN PSQLQTPASQ AQANSAVQHA YLPSGWNSFR GYPSEIQMMA 

      1090       1100       1110       1120       1130       1140 
LPQGQYVIAE AAVGTPVTPV SSGQVKAVTQ THYVISEGQG VLDMKKSSSL AEEATPNPDH 

      1150       1160       1170 
MEQPASNSSQ TTQYIITTTT NMNGSSEVHI SKP 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC168013 mRNA. Translation: AAI68013.1.
RefSeqNP_001135541.1. NM_001142069.1.
UniGeneStr.58567.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100216084.
KEGGxtr:100216084.

Organism-specific databases

CTD56980.
XenbaseXB-GENE-985864. prdm10.

Phylogenomic databases

HOVERGENHBG053664.

Family and domain databases

Gene3D3.30.160.60. 5 hits.
InterProIPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamPF00096. zf-C2H2. 4 hits.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 10 hits.
[Graphical view]
PROSITEPS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 10 hits.
PS50157. ZINC_FINGER_C2H2_2. 10 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePRD10_XENTR
AccessionPrimary (citable) accession number: B4F6U4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: September 23, 2008
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families