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B4F6N5

- B4F6N5_XENTR

UniProt

B4F6N5 - B4F6N5_XENTR

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Protein
DNA ligase
Gene
lig3
Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
  4. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:lig3Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-5788004. lig3.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000007653.
HOVERGENiHBG005515.
KOiK10776.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4F6N5-1 [UniParc]FASTAAdd to Basket

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MRAFLRLLAY QTKRTLGQSL TKVPLRVIFH ACWSQSPLHS ALHFQFFLRV    50
THFSNMAEQR YCVEYAKRGT AGCKKCKEKI GKGLVRIGKI VPNPFSESAG 100
DMKEWYHIKC MFEKLERARA TTKKIDDLTE LEGWQELQDC DKNLISQHVT 150
ELATKTAATP RKKTPSKEKQ SPAVQGTTST TAPAASPSLK FSGFSAKPSQ 200
SSSPPSSSTG SSLSTAKCDP KHKDCLLREF RKLCAMVAEQ PSYNSKTQII 250
RDFLTKGTSG DGFHGDTYLT VKLLLPGVIK SVYNLNDKQI VKHFSRIFNC 300
NQEEMVRDLE QGDVSETVRI FFEESKCFAP ASKSLLTIHE VDDLLTKLSK 350
MTKEEDQQNV LEDIAHRCTS NDLKCIIRLI KHDLKMNSGA KHVLDALDPN 400
AYDAFKASRN LGDVVERVLR NEQQAPGMKR TLSVQASLMT PVQPMLAEAC 450
KSIEYAMKKC PNGMYAEIKY DGERVQVHKN GDHFSYFSRS LKPVLPHKVA 500
HFKDFIPKAF PGGNSMILDA EVLLIDTNTG KPLPFGTLGV HKKAAFKDAN 550
VCLFVFDCIY FNGVSLMDRP LSERRKFMRD NMVEIPNHIL FSEMKHVTKA 600
SDLADMITRV IREGLEGLVL KDLKSNYEPG KRHWLKVKKD YLNEGAMADT 650
ADLAVLGAYY GKGANGGIMS IFLMGCYDPE SQKWCTVTKC SSGYDDATLQ 700
RLQKELNMVK ISKDPSKIPS WLKINKNYFP DFIIHDPKKA PIWEITGAEY 750
SKAEAHTAAG LSIRFPRCTR FRDDKDWKTA TTLQQLKELY RLSKEKSDFN 800
ITATSSQDED GSSESSSREN EGNSRQTASG SMVKKSKNAP SKSPGKDKTS 850
ESTKLPPPQK KEELPKAEKR KSQTPKTVQS KKVRKQHIEK CIQ 893
Length:893
Mass (Da):100,464
Last modified:September 23, 2008 - v1
Checksum:i797F437FB781E248
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC167946 mRNA. Translation: AAI67946.1.
RefSeqiNP_001016351.2. NM_001016351.3.
UniGeneiStr.26611.

Genome annotation databases

GeneIDi549105.
KEGGixtr:549105.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC167946 mRNA. Translation: AAI67946.1 .
RefSeqi NP_001016351.2. NM_001016351.3.
UniGenei Str.26611.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 549105.
KEGGi xtr:549105.

Organism-specific databases

CTDi 3980.
Xenbasei XB-GENE-5788004. lig3.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000007653.
HOVERGENi HBG005515.
KOi K10776.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: N6Imported.
    Tissue: Fat bodyImported.

Entry informationi

Entry nameiB4F6N5_XENTR
AccessioniPrimary (citable) accession number: B4F6N5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 16, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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