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B4F6N5

- B4F6N5_XENTR

UniProt

B4F6N5 - B4F6N5_XENTR

Protein

DNA ligase

Gene

lig3

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:lig3Imported
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

    Organism-specific databases

    XenbaseiXB-GENE-5788004. lig3.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000007653.
    HOVERGENiHBG005515.
    KOiK10776.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR001510. Znf_PARP.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4F6N5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRAFLRLLAY QTKRTLGQSL TKVPLRVIFH ACWSQSPLHS ALHFQFFLRV    50
    THFSNMAEQR YCVEYAKRGT AGCKKCKEKI GKGLVRIGKI VPNPFSESAG 100
    DMKEWYHIKC MFEKLERARA TTKKIDDLTE LEGWQELQDC DKNLISQHVT 150
    ELATKTAATP RKKTPSKEKQ SPAVQGTTST TAPAASPSLK FSGFSAKPSQ 200
    SSSPPSSSTG SSLSTAKCDP KHKDCLLREF RKLCAMVAEQ PSYNSKTQII 250
    RDFLTKGTSG DGFHGDTYLT VKLLLPGVIK SVYNLNDKQI VKHFSRIFNC 300
    NQEEMVRDLE QGDVSETVRI FFEESKCFAP ASKSLLTIHE VDDLLTKLSK 350
    MTKEEDQQNV LEDIAHRCTS NDLKCIIRLI KHDLKMNSGA KHVLDALDPN 400
    AYDAFKASRN LGDVVERVLR NEQQAPGMKR TLSVQASLMT PVQPMLAEAC 450
    KSIEYAMKKC PNGMYAEIKY DGERVQVHKN GDHFSYFSRS LKPVLPHKVA 500
    HFKDFIPKAF PGGNSMILDA EVLLIDTNTG KPLPFGTLGV HKKAAFKDAN 550
    VCLFVFDCIY FNGVSLMDRP LSERRKFMRD NMVEIPNHIL FSEMKHVTKA 600
    SDLADMITRV IREGLEGLVL KDLKSNYEPG KRHWLKVKKD YLNEGAMADT 650
    ADLAVLGAYY GKGANGGIMS IFLMGCYDPE SQKWCTVTKC SSGYDDATLQ 700
    RLQKELNMVK ISKDPSKIPS WLKINKNYFP DFIIHDPKKA PIWEITGAEY 750
    SKAEAHTAAG LSIRFPRCTR FRDDKDWKTA TTLQQLKELY RLSKEKSDFN 800
    ITATSSQDED GSSESSSREN EGNSRQTASG SMVKKSKNAP SKSPGKDKTS 850
    ESTKLPPPQK KEELPKAEKR KSQTPKTVQS KKVRKQHIEK CIQ 893
    Length:893
    Mass (Da):100,464
    Last modified:September 23, 2008 - v1
    Checksum:i797F437FB781E248
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC167946 mRNA. Translation: AAI67946.1.
    RefSeqiNP_001016351.2. NM_001016351.3.
    UniGeneiStr.26611.

    Genome annotation databases

    GeneIDi549105.
    KEGGixtr:549105.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC167946 mRNA. Translation: AAI67946.1 .
    RefSeqi NP_001016351.2. NM_001016351.3.
    UniGenei Str.26611.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 549105.
    KEGGi xtr:549105.

    Organism-specific databases

    CTDi 3980.
    Xenbasei XB-GENE-5788004. lig3.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000007653.
    HOVERGENi HBG005515.
    KOi K10776.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR001510. Znf_PARP.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: N6Imported.
      Tissue: Fat bodyImported.

    Entry informationi

    Entry nameiB4F6N5_XENTR
    AccessioniPrimary (citable) accession number: B4F6N5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)