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B4F6J6 (ATAD1_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATPase family AAA domain-containing protein 1

EC=3.6.1.3
Gene names
Name:atad1
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner By similarity.

Catalytic activity

ATP + H2O = ADP + phosphate.

Subcellular location

Peroxisome By similarity. Cell junctionsynapsepostsynaptic cell membrane By similarity.

Sequence similarities

Belongs to the AAA ATPase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 360360ATPase family AAA domain-containing protein 1
PRO_0000416487

Regions

Nucleotide binding133 – 1408ATP Potential

Amino acid modifications

Modified residue1461Phosphothreonine By similarity
Modified residue3221Phosphoserine By similarity

Experimental info

Sequence conflict1851Q → H in AAI67903. Ref.2

Sequences

Sequence LengthMass (Da)Tools
B4F6J6 [UniParc].

Last modified April 18, 2012. Version 2.
Checksum: 428543C0E8C7A0DE

FASTA36040,492
        10         20         30         40         50         60 
MVHGEAFSRP LSRNEVVGLI FRLTIFGAVT YFTIKWMVDA IDPTRKQKVE AQKQAEKLMR 

        70         80         90        100        110        120 
QIGVKNVKLT EYEMSIAAHL VDPLSMLVTW SDIAGLDDVI TDLKDTVILP IRKRYLFENS 

       130        140        150        160        170        180 
RLLQPPKGVL LYGPPGCGKT MIAKATAKEA GCRFINLQPS TLTDKWYGES QKLAAAVFSL 

       190        200        210        220        230        240 
AVKLQPSIIF IDEIDSFLRS RSSSDHEATA MMKAQFMSLW DGLDTDFNCQ VIVMGATNRP 

       250        260        270        280        290        300 
QDLDTAIMRR MPTRFHINQP SLKQREAILD LILRNESVDS HVDLMEIARG SDGFSGSDLK 

       310        320        330        340        350        360 
EMCRDAALLC VRDSVNNSSE ESPCEEIRPI HQQDLLRAID KMKRSKSATN QNVLMHVSLD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAMC01046255 Genomic DNA. No translation available.
BC167903 mRNA. Translation: AAI67903.1.
RefSeqNP_001135501.1. NM_001142029.1.
UniGeneStr.19240.

3D structure databases

ProteinModelPortalB4F6J6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000020353.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100216041.
KEGGxtr:100216041.

Organism-specific databases

CTD84896.
XenbaseXB-GENE-5779938. atad1.

Phylogenomic databases

eggNOGCOG0464.
HOGENOMHOG000225141.
HOVERGENHBG057074.
OMAYNCQVIV.
OrthoDBEOG7SR4MJ.

Gene expression databases

BgeeB4F6J6.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00004. AAA. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATAD1_XENTR
AccessionPrimary (citable) accession number: B4F6J6
Secondary accession number(s): F7CNN7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: April 18, 2012
Last modified: May 14, 2014
This is version 37 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families