Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B4F6J6

- ATAD1_XENTR

UniProt

B4F6J6 - ATAD1_XENTR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

ATPase family AAA domain-containing protein 1

Gene

atad1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner (By similarity).By similarity

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi133 – 1408ATPSequence Analysis

GO - Molecular functioni

  1. ATPase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATPase family AAA domain-containing protein 1 (EC:3.6.1.3)
Gene namesi
Name:atad1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
ProteomesiUP000008143: Unplaced

Organism-specific databases

XenbaseiXB-GENE-5779938. atad1.

Subcellular locationi

Peroxisome By similarity. Cell junctionsynapsepostsynaptic cell membrane By similarity

GO - Cellular componenti

  1. cell junction Source: UniProtKB-KW
  2. peroxisome Source: UniProtKB-KW
  3. postsynaptic membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Peroxisome, Postsynaptic cell membrane, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 360360ATPase family AAA domain-containing protein 1PRO_0000416487Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei146 – 1461PhosphothreonineBy similarity
Modified residuei322 – 3221PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Expressioni

Gene expression databases

BgeeiB4F6J6.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000020353.

Structurei

3D structure databases

ProteinModelPortaliB4F6J6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Phylogenomic databases

eggNOGiCOG0464.
HOGENOMiHOG000225141.
HOVERGENiHBG057074.
InParanoidiB4F6J6.
OMAiYNCQVIV.
OrthoDBiEOG7SR4MJ.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4F6J6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVHGEAFSRP LSRNEVVGLI FRLTIFGAVT YFTIKWMVDA IDPTRKQKVE
60 70 80 90 100
AQKQAEKLMR QIGVKNVKLT EYEMSIAAHL VDPLSMLVTW SDIAGLDDVI
110 120 130 140 150
TDLKDTVILP IRKRYLFENS RLLQPPKGVL LYGPPGCGKT MIAKATAKEA
160 170 180 190 200
GCRFINLQPS TLTDKWYGES QKLAAAVFSL AVKLQPSIIF IDEIDSFLRS
210 220 230 240 250
RSSSDHEATA MMKAQFMSLW DGLDTDFNCQ VIVMGATNRP QDLDTAIMRR
260 270 280 290 300
MPTRFHINQP SLKQREAILD LILRNESVDS HVDLMEIARG SDGFSGSDLK
310 320 330 340 350
EMCRDAALLC VRDSVNNSSE ESPCEEIRPI HQQDLLRAID KMKRSKSATN
360
QNVLMHVSLD
Length:360
Mass (Da):40,492
Last modified:April 18, 2012 - v2
Checksum:i428543C0E8C7A0DE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti185 – 1851Q → H in AAI67903. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAMC01046255 Genomic DNA. No translation available.
BC167903 mRNA. Translation: AAI67903.1.
RefSeqiNP_001135501.1. NM_001142029.1.
UniGeneiStr.19240.

Genome annotation databases

GeneIDi100216041.
KEGGixtr:100216041.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAMC01046255 Genomic DNA. No translation available.
BC167903 mRNA. Translation: AAI67903.1 .
RefSeqi NP_001135501.1. NM_001142029.1.
UniGenei Str.19240.

3D structure databases

ProteinModelPortali B4F6J6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 8364.ENSXETP00000020353.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100216041.
KEGGi xtr:100216041.

Organism-specific databases

CTDi 84896.
Xenbasei XB-GENE-5779938. atad1.

Phylogenomic databases

eggNOGi COG0464.
HOGENOMi HOG000225141.
HOVERGENi HBG057074.
InParanoidi B4F6J6.
OMAi YNCQVIV.
OrthoDBi EOG7SR4MJ.

Gene expression databases

Bgeei B4F6J6.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00004. AAA. 1 hit.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00674. AAA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo.

Entry informationi

Entry nameiATAD1_XENTR
AccessioniPrimary (citable) accession number: B4F6J6
Secondary accession number(s): F7CNN7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: April 18, 2012
Last modified: October 29, 2014
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3