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B4F183 (CAPP_PROMH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:PMI3227
OrganismProteus mirabilis (strain HI4320) [Complete proteome] [HAMAP]
Taxonomic identifier529507 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus

Protein attributes

Sequence length878 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 878878Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000129836

Sites

Active site1371 By similarity
Active site5451 By similarity

Sequences

Sequence LengthMass (Da)Tools
B4F183 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 208C42D3EA1C9AA3

FASTA87898,678
        10         20         30         40         50         60 
MNQQYSAMRS NVSMLGKLLG DTIKEALGEE ILDKVESIRK LSKSSRAGNE VQRQKLLLTL 

        70         80         90        100        110        120 
QNLSNDELLP VARAFNQFLN LTNVAEQYHS ISPHGEAASN PVALAKLIER LKDKNFTNQQ 

       130        140        150        160        170        180 
LKQAVEQISI ELVLTAHPTE IARRTLIHKL VEVNTCLSQL DHDDLADYER TNIMRRLRQL 

       190        200        210        220        230        240 
VAQSWHTDEI RKIRPTPIDE AKWGFAVVEN SLWEGVPAFL REFNEQLEES IDYNLPVEAS 

       250        260        270        280        290        300 
PIRFTSWMGG DRDGNPNVTA EITRHALLLS RWKAADLFLN DIQVLVSELS MTESTPELRE 

       310        320        330        340        350        360 
LAGGADVAEP YREIAKQLRT RLQVTRDYLE QRIKGQQSLP PEGLLIDNSA LWEPLYACYQ 

       370        380        390        400        410        420 
SLHQCGMRII ANGQLLDTLR RIRCFGLQLV RLDIRQESTN HTEALSELTQ YLELGDYASW 

       430        440        450        460        470        480 
SEEQKQTFLL TELNSKRPLI PTHWQPSEAT KEVFETCRVI AESPKDSIAS YVISMAKVPS 

       490        500        510        520        530        540 
DVLAVKLLLK EAGADIRLPV APLFETLEDL NNAESVMTRL FDIPWYRDLI DNKQMVMIGY 

       550        560        570        580        590        600 
SDSAKDAGVM AASWAQYRAQ DALIKLCEKS GVTLTLFHGR GGTIGRGGAP AHAALLSQPP 

       610        620        630        640        650        660 
GSLKGGLRVT EQGEMIRFKF GLPQVTISSL AHYAGAILEA NLLPPPEPKT AWIEVMDALS 

       670        680        690        700        710        720 
DVSCEMYRGY VRGEKDFVPY FRAATPEGEL GKLPLGSRPA KRRPTGGVET LRAIPWIFAW 

       730        740        750        760        770        780 
TQNRLMLPAW LGAGAALQHE IDNGKQAVLD DMCENWPFFN TRIAMLEMVY AKADLWLAEY 

       790        800        810        820        830        840 
YDQRLVEENL WPLGAKLRQQ LSDDIKSVLA ISKDEHLMAD LPWVAESIAL RNVYTDPLNV 

       850        860        870 
LQAELLQRSR THSESDPRIE QALMVTIAGI AAGMRNTG 

« Hide

References

[1]"Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility."
Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S., Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Walker D., Whithead S. expand/collapse author list , Thomson N.R., Rather P.N., Parkhill J., Mobley H.L.T.
J. Bacteriol. 190:4027-4037(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI4320.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM942759 Genomic DNA. Translation: CAR46321.1.
RefSeqYP_002152912.1. NC_010554.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING529507.PMI3227.

Proteomic databases

PRIDEB4F183.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR46321; CAR46321; PMI3227.
GeneID6801836.
KEGGpmr:PMI3227.
PATRIC20521132. VBIProMir120933_3154.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238648.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycPMIR529507:GJIW-3284-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_PROMH
AccessionPrimary (citable) accession number: B4F183
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families