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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Proteus mirabilis (strain HI4320)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei545 – 5451UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciPMIR529507:GJIW-3284-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PMI3227
OrganismiProteus mirabilis (strain HI4320)
Taxonomic identifieri529507 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus
ProteomesiUP000008319 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 878878Phosphoenolpyruvate carboxylasePRO_1000129836Add
BLAST

Proteomic databases

PRIDEiB4F183.

Interactioni

Protein-protein interaction databases

STRINGi529507.PMI3227.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4F183-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQQYSAMRS NVSMLGKLLG DTIKEALGEE ILDKVESIRK LSKSSRAGNE
60 70 80 90 100
VQRQKLLLTL QNLSNDELLP VARAFNQFLN LTNVAEQYHS ISPHGEAASN
110 120 130 140 150
PVALAKLIER LKDKNFTNQQ LKQAVEQISI ELVLTAHPTE IARRTLIHKL
160 170 180 190 200
VEVNTCLSQL DHDDLADYER TNIMRRLRQL VAQSWHTDEI RKIRPTPIDE
210 220 230 240 250
AKWGFAVVEN SLWEGVPAFL REFNEQLEES IDYNLPVEAS PIRFTSWMGG
260 270 280 290 300
DRDGNPNVTA EITRHALLLS RWKAADLFLN DIQVLVSELS MTESTPELRE
310 320 330 340 350
LAGGADVAEP YREIAKQLRT RLQVTRDYLE QRIKGQQSLP PEGLLIDNSA
360 370 380 390 400
LWEPLYACYQ SLHQCGMRII ANGQLLDTLR RIRCFGLQLV RLDIRQESTN
410 420 430 440 450
HTEALSELTQ YLELGDYASW SEEQKQTFLL TELNSKRPLI PTHWQPSEAT
460 470 480 490 500
KEVFETCRVI AESPKDSIAS YVISMAKVPS DVLAVKLLLK EAGADIRLPV
510 520 530 540 550
APLFETLEDL NNAESVMTRL FDIPWYRDLI DNKQMVMIGY SDSAKDAGVM
560 570 580 590 600
AASWAQYRAQ DALIKLCEKS GVTLTLFHGR GGTIGRGGAP AHAALLSQPP
610 620 630 640 650
GSLKGGLRVT EQGEMIRFKF GLPQVTISSL AHYAGAILEA NLLPPPEPKT
660 670 680 690 700
AWIEVMDALS DVSCEMYRGY VRGEKDFVPY FRAATPEGEL GKLPLGSRPA
710 720 730 740 750
KRRPTGGVET LRAIPWIFAW TQNRLMLPAW LGAGAALQHE IDNGKQAVLD
760 770 780 790 800
DMCENWPFFN TRIAMLEMVY AKADLWLAEY YDQRLVEENL WPLGAKLRQQ
810 820 830 840 850
LSDDIKSVLA ISKDEHLMAD LPWVAESIAL RNVYTDPLNV LQAELLQRSR
860 870
THSESDPRIE QALMVTIAGI AAGMRNTG
Length:878
Mass (Da):98,678
Last modified:September 23, 2008 - v1
Checksum:i208C42D3EA1C9AA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM942759 Genomic DNA. Translation: CAR46321.1.
RefSeqiWP_004246402.1. NC_010554.1.
YP_002152912.1. NC_010554.1.

Genome annotation databases

EnsemblBacteriaiCAR46321; CAR46321; PMI3227.
GeneIDi6801836.
KEGGipmr:PMI3227.
PATRICi20521132. VBIProMir120933_3154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM942759 Genomic DNA. Translation: CAR46321.1.
RefSeqiWP_004246402.1. NC_010554.1.
YP_002152912.1. NC_010554.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi529507.PMI3227.

Proteomic databases

PRIDEiB4F183.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR46321; CAR46321; PMI3227.
GeneIDi6801836.
KEGGipmr:PMI3227.
PATRICi20521132. VBIProMir120933_3154.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPMIR529507:GJIW-3284-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI4320.

Entry informationi

Entry nameiCAPP_PROMH
AccessioniPrimary (citable) accession number: B4F183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: May 27, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.