Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Proteus mirabilis (strain HI4320)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciPMIR529507:GJIW-1711-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:PMI1687
OrganismiProteus mirabilis (strain HI4320)
Taxonomic identifieri529507 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus
Proteomesi
  • UP000008319 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalUniRule annotationAdd
BLAST
Transmembranei52 – 7221HelicalUniRule annotationAdd
BLAST
Transmembranei90 – 11021HelicalUniRule annotationAdd
BLAST
Transmembranei113 – 13321HelicalUniRule annotationAdd
BLAST
Transmembranei149 – 16921HelicalUniRule annotationAdd
BLAST
Transmembranei171 – 19121HelicalUniRule annotationAdd
BLAST
Transmembranei219 – 23921HelicalUniRule annotationAdd
BLAST
Transmembranei254 – 27421HelicalUniRule annotationAdd
BLAST
Transmembranei288 – 30821HelicalUniRule annotationAdd
BLAST
Transmembranei318 – 33821HelicalUniRule annotationAdd
BLAST
Transmembranei376 – 39621HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Multidrug resistance protein MdtGPRO_0000414581Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi529507.PMI1687.

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFITTMII.
OrthoDBiEOG6VF34T.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4EYY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLKPRNNSW KQNLYIVWFG CFLTGAGFSL IMPFLPLYVE ELGIKDHESL
60 70 80 90 100
NLWTGVAFSI TFLFSAIAAP FWGKLSDRKG RKLMLLRSAL GMAIVMVLIG
110 120 130 140 150
FAQNIWQLLI LRALLGVLGG FVPNANALIA TQVPVKKSGW ALGTLSTGAV
160 170 180 190 200
SGALIGPLIG GILADLYGLR PVFFITAAVL FICFIVTLFF VSENFTPVSK
210 220 230 240 250
KDALSTQQVF SSLKNKRLVI CLFFTTMIIQ VATGSVTPIL TLYIRDLAGS
260 270 280 290 300
ISNLAFISGV IASVPGIAAL ISAPRFGKLG DRIGPDKVLI FTLGLSIFML
310 320 330 340 350
IPMALVSNYW ELGALRFLLG AVNAAMLPAV QTLILYNITP AIAGRIFSYN
360 370 380 390 400
QALRDVGNVT GPLMGAFVAA NYGFRAVFYF TAAVVFFNLI YSWISFRTPQ

RK
Length:402
Mass (Da):43,721
Last modified:September 23, 2008 - v1
Checksum:i3A46F4B6CDCBED01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM942759 Genomic DNA. Translation: CAR43519.1.
RefSeqiWP_012368071.1. NC_010554.1.

Genome annotation databases

EnsemblBacteriaiCAR43519; CAR43519; PMI1687.
GeneIDi6801162.
KEGGipmr:PMI1687.
PATRICi20518027. VBIProMir120933_1638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM942759 Genomic DNA. Translation: CAR43519.1.
RefSeqiWP_012368071.1. NC_010554.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi529507.PMI1687.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR43519; CAR43519; PMI1687.
GeneIDi6801162.
KEGGipmr:PMI1687.
PATRICi20518027. VBIProMir120933_1638.

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFITTMII.
OrthoDBiEOG6VF34T.

Enzyme and pathway databases

BioCyciPMIR529507:GJIW-1711-MONOMER.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI4320.

Entry informationi

Entry nameiMDTG_PROMH
AccessioniPrimary (citable) accession number: B4EYY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: September 23, 2008
Last modified: November 11, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.