Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B4EXS0 (B4EXS0_PROMH) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 RuleBase RU000544 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding87 – 904ATP By similarity HAMAP-Rule MF_00124

Sites

Active site881Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1821Zinc By similarity HAMAP-Rule MF_00124
Metal binding1851Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
B4EXS0 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 2EA2D43DCED2234F

FASTA19822,163
        10         20         30         40         50         60 
MAQLYFYYSA MNAGKSTSLL QSSYNYNERG MRTLIFTAAI DTRFAKGKVT SRIGLSADAL 

        70         80         90        100        110        120 
LFSDDMNIRD AILAENNKEP IHCVLIDECQ FLTKAHVEQL CEITDSYDIP VLTYGLRTDF 

       130        140        150        160        170        180 
RGELFTGSAY LLAWADKLVE LKTVCYCGRK ANKVLRLAAN GKVLSDGAQV EIGGNEKYVS 

       190 
VCRKHYTEAT LKGRIEQL 

« Hide

References

[1]"Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility."
Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S., Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Walker D., Whithead S. expand/collapse author list , Thomson N.R., Rather P.N., Parkhill J., Mobley H.L.T.
J. Bacteriol. 190:4027-4037(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI4320 EMBL CAR43121.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM942759 Genomic DNA. Translation: CAR43121.1.
RefSeqYP_002151218.1. NC_010554.1.

3D structure databases

ProteinModelPortalB4EXS0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING529507.PMI1487.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR43121; CAR43121; PMI1487.
GeneID6802547.
KEGGpmr:PMI1487.
PATRIC20517599. VBIProMir120933_1435.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMAELKTVCH.
OrthoDBEOG69D3J2.

Enzyme and pathway databases

BioCycPMIR529507:GJIW-1498-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4EXS0_PROMH
AccessionPrimary (citable) accession number: B4EXS0
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)