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B4EWA1 (DEOD_PROMH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:PMI2413
OrganismProteus mirabilis (strain HI4320) [Complete proteome] [HAMAP]
Taxonomic identifier529507 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_1000186212

Sequences

Sequence LengthMass (Da)Tools
B4EWA1 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: CE198BF8D9AE240B

FASTA23825,933
        10         20         30         40         50         60 
MATPHINAEM GDFADVVLMP GDPLRAKYIA ETFLQDVRQV NNVRGMLGFT GTYKGRKISV 

        70         80         90        100        110        120 
MGHGMGIPSC SIYAKELITD FGVKVIIRVG SCGAVLPDVE LRDVVIGMGA CTDSKVNRLR 

       130        140        150        160        170        180 
FKDQDFAAIA DFELVQNAVS AAKAKDIKVR VGNIFSADLF YSPDPEMFDV MEKYGILGVE 

       190        200        210        220        230 
MEAAGIYGVA AEYGARALTI CTVSDHIKKG TQTTSEERQT TFNEMIEIAL ESVLLLED 

« Hide

References

[1]"Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility."
Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S., Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T., Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Walker D., Whithead S. expand/collapse author list , Thomson N.R., Rather P.N., Parkhill J., Mobley H.L.T.
J. Bacteriol. 190:4027-4037(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI4320.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM942759 Genomic DNA. Translation: CAR44770.1.
RefSeqYP_002152131.1. NC_010554.1.

3D structure databases

ProteinModelPortalB4EWA1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING529507.PMI2413.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR44770; CAR44770; PMI2413.
GeneID6801110.
KEGGpmr:PMI2413.
PATRIC20519524. VBIProMir120933_2362.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0813.
HOGENOMHOG000274896.
KOK03784.
OMASFETHAF.
OrthoDBEOG6BKJC5.

Enzyme and pathway databases

BioCycPMIR529507:GJIW-2462-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_PROMH
AccessionPrimary (citable) accession number: B4EWA1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families