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B4EUV6

- RECA_PROMH

UniProt

B4EUV6 - RECA_PROMH

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Protein

Protein RecA

Gene

recA

Organism
Proteus mirabilis (strain HI4320)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi67 – 748ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. DNA-dependent ATPase activity Source: UniProtKB-HAMAP
  4. single-stranded DNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA recombination Source: UniProtKB-HAMAP
  2. DNA repair Source: UniProtKB-HAMAP
  3. SOS response Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMIR529507:GJIW-371-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:PMI0375
OrganismiProteus mirabilis (strain HI4320)
Taxonomic identifieri529507 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus
ProteomesiUP000008319: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Protein RecAPRO_1000114355Add
BLAST

Proteomic databases

PRIDEiB4EUV6.

Interactioni

Protein-protein interaction databases

STRINGi529507.PMI0375.

Structurei

3D structure databases

ProteinModelPortaliB4EUV6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0468.
HOGENOMiHOG000264120.
KOiK03553.
OMAiNTYGELI.
OrthoDBiEOG6ZKXNZ.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4EUV6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIDENKQKA LAAALGQIEK QFGKGSIMRL GEDRSMNVET ISTGSLSLDV
60 70 80 90 100
ALGAGGLPRG RIVEIYGPES SGKTTLTLQV IASAQREGKI CAFIDAEHAL
110 120 130 140 150
DPIYAQKLGV DIDNLLCSQP DTGEQALEIC DALSRSGAVD VIVVDSVAAL
160 170 180 190 200
TPKAEIEGEI GDSHVGLAAR MMSQAMRKLA GNLKNSNTLL IFINQIRMKI
210 220 230 240 250
GVMFGNPETT TGGNALKFYA SVRLDIRRIG SVKNGDEVIG SETRVKVVKN
260 270 280 290 300
KVAAPFKQAE FQIMYGEGIN TYGELIDLGV KHKLVEKAGA WYSYNGEKIG
310 320 330 340 350
QGKANATNYL KEHPEMYNEL NTKLREMLLN HAGEFTSAAD FAGEESDSDA

DDTKE
Length:355
Mass (Da):38,219
Last modified:September 23, 2008 - v1
Checksum:i73F6D0B215F7E9D8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM942759 Genomic DNA. Translation: CAR40963.1.
RefSeqiYP_002150147.1. NC_010554.1.

Genome annotation databases

EnsemblBacteriaiCAR40963; CAR40963; PMI0375.
GeneIDi6803560.
KEGGipmr:PMI0375.
PATRICi20515397. VBIProMir120933_0358.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM942759 Genomic DNA. Translation: CAR40963.1 .
RefSeqi YP_002150147.1. NC_010554.1.

3D structure databases

ProteinModelPortali B4EUV6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 529507.PMI0375.

Proteomic databases

PRIDEi B4EUV6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR40963 ; CAR40963 ; PMI0375 .
GeneIDi 6803560.
KEGGi pmr:PMI0375.
PATRICi 20515397. VBIProMir120933_0358.

Phylogenomic databases

eggNOGi COG0468.
HOGENOMi HOG000264120.
KOi K03553.
OMAi NTYGELI.
OrthoDBi EOG6ZKXNZ.

Enzyme and pathway databases

BioCyci PMIR529507:GJIW-371-MONOMER.

Family and domain databases

Gene3Di 3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00268. RecA.
InterProi IPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view ]
PANTHERi PTHR22942:SF1. PTHR22942:SF1. 1 hit.
Pfami PF00154. RecA. 1 hit.
[Graphical view ]
PRINTSi PR00142. RECA.
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsi TIGR02012. tigrfam_recA. 1 hit.
PROSITEi PS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI4320.

Entry informationi

Entry nameiRECA_PROMH
AccessioniPrimary (citable) accession number: B4EUV6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3