Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B4EUL1

- ARNT1_PROMH

UniProt

B4EUL1 - ARNT1_PROMH

Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 1

Gene

arnT1

Organism
Proteus mirabilis (strain HI4320)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

    Catalytic activityi

    4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. mannosyltransferase activity Source: InterPro
    2. transferase activity, transferring pentosyl groups Source: InterPro

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-HAMAP
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
    3. protein O-linked glycosylation Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciPMIR529507:GJIW-275-MONOMER.
    UniPathwayiUPA00037.

    Protein family/group databases

    CAZyiGT83. Glycosyltransferase Family 83.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 1UniRule annotation (EC:2.4.2.43UniRule annotation)
    Alternative name(s):
    4-amino-4-deoxy-L-arabinose lipid A transferase 1UniRule annotation
    Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
    Undecaprenyl phosphate-alpha-L-Ara4N transferase 1UniRule annotation
    Gene namesi
    Name:arnT1UniRule annotation
    Ordered Locus Names:PMI0275
    OrganismiProteus mirabilis (strain HI4320)
    Taxonomic identifieri529507 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeProteus
    ProteomesiUP000008319: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 548548Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 1PRO_0000380013Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi529507.PMI0275.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalUniRule annotationAdd
    BLAST
    Transmembranei89 – 10921HelicalUniRule annotationAdd
    BLAST
    Transmembranei114 – 13421HelicalUniRule annotationAdd
    BLAST
    Transmembranei137 – 15721HelicalUniRule annotationAdd
    BLAST
    Transmembranei180 – 20021HelicalUniRule annotationAdd
    BLAST
    Transmembranei214 – 23421HelicalUniRule annotationAdd
    BLAST
    Transmembranei263 – 28321HelicalUniRule annotationAdd
    BLAST
    Transmembranei292 – 31221HelicalUniRule annotationAdd
    BLAST
    Transmembranei314 – 33421HelicalUniRule annotationAdd
    BLAST
    Transmembranei347 – 36721HelicalUniRule annotationAdd
    BLAST
    Transmembranei382 – 40221HelicalUniRule annotationAdd
    BLAST
    Transmembranei405 – 42521HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 83 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1807.
    HOGENOMiHOG000273002.
    OMAiYNILDPI.
    OrthoDBiEOG6NKQWN.

    Family and domain databases

    HAMAPiMF_01165. ArnT_transfer.
    InterProiIPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view]
    PfamiPF02366. PMT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4EUL1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNIAMTERYK WLLFFLFILL TYFIPLETRL LWQPDEIRYA EISREMLVSG    50
    NWSVPYLLDI RYFEKPVLGY WINCIAQWLF GESHFAVRIV VVTSTLLTGW 100
    LIYKAAMVVW RNSALAFNAM TVFLSSFLVL AIGTYNILDP IVTLFVTAAM 150
    YSFLVALSTP NKKGKIIAYM GIGFFCALGF LTKGFIAVVL PALVFLVMAI 200
    SQARFKEVVC YSSIALLALA ITAGPWVITV ALQAPDYWNY FFWVEHVQRF 250
    IAKESARSQP TWFYIPIVIL GVLPWLGFLF GALKSAFSLK KGTLYFLLWF 300
    TLFFAFFSAS KGKLLTYMLP CFVPLSILIA HYIEELKDRP DEKISKVNAS 350
    INIAFGLMGI SAVIYSLYSA KFALYDTNET LKIVLAISGF LFWSVIGAGA 400
    LFRQTQFLTM FCSIGLSLVI GYAIPEKIES RSTPENIIQR YYEPLSNKSY 450
    LLTDEVGIGT SLAWGLKRTD IRLTETKGEL AYGLNYPDVK NKYYSLEQLL 500
    ALIEANQYKG VAIVLVRPDR KQILTKLTTL KEKPIVEKEG DLTLVFFN 548
    Length:548
    Mass (Da):62,263
    Last modified:September 23, 2008 - v1
    Checksum:iB7084221A0FD460C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM942759 Genomic DNA. Translation: CAR40745.1.
    RefSeqiWP_012367533.1. NC_010554.1.
    YP_002150055.1. NC_010554.1.

    Genome annotation databases

    EnsemblBacteriaiCAR40745; CAR40745; PMI0275.
    GeneIDi6802481.
    KEGGipmr:PMI0275.
    PATRICi20515209. VBIProMir120933_0265.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM942759 Genomic DNA. Translation: CAR40745.1 .
    RefSeqi WP_012367533.1. NC_010554.1.
    YP_002150055.1. NC_010554.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 529507.PMI0275.

    Protein family/group databases

    CAZyi GT83. Glycosyltransferase Family 83.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR40745 ; CAR40745 ; PMI0275 .
    GeneIDi 6802481.
    KEGGi pmr:PMI0275.
    PATRICi 20515209. VBIProMir120933_0265.

    Phylogenomic databases

    eggNOGi COG1807.
    HOGENOMi HOG000273002.
    OMAi YNILDPI.
    OrthoDBi EOG6NKQWN.

    Enzyme and pathway databases

    UniPathwayi UPA00037 .
    BioCyci PMIR529507:GJIW-275-MONOMER.

    Family and domain databases

    HAMAPi MF_01165. ArnT_transfer.
    InterProi IPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view ]
    Pfami PF02366. PMT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HI4320.

    Entry informationi

    Entry nameiARNT1_PROMH
    AccessioniPrimary (citable) accession number: B4EUL1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3