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B4ENA5 (XYLA_BURCJ) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:BceJ2315_66270
ORF Names:BCAS0355
OrganismBurkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]
Taxonomic identifier216591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Xylose isomerase HAMAP MF_00455
PRO_1000200283

Sites

Active site1001 By similarity
Active site1031 By similarity
Metal binding2311Magnesium 1 By similarity
Metal binding2671Magnesium 1 By similarity
Metal binding2671Magnesium 2 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2951Magnesium 1 By similarity
Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3381Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
B4ENA5 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 3C0E3557C579806F

FASTA44049,540
        10         20         30         40         50         60 
MSYFEHIPAI RYEGPQSDNP LAYHHYDPDK RVLGKTLAEH LRIAVCYWHT FVWPGHDIFG 

        70         80         90        100        110        120 
QAAFRRPWQQ PGDALERARM KADAAFEFFT KLGTPFYTFH DTDVAPEGDS LREYAANFAR 

       130        140        150        160        170        180 
MVDYLGERQQ ASGVRLLWGT ANLFSHPRFA AGAATNPNPD VFAWAATQVC HALDATHRLG 

       190        200        210        220        230        240 
GENYVLWGGR EGYETLLNTD LKRERDQFAR FLSMVVEHKH RIGFKGALLI EPKPQEPTKH 

       250        260        270        280        290        300 
QYDYDVATVH GFLVQYGLQN EIRVNIEANH ATLAGHSFHH EIANAFALGV FGSVDANRGD 

       310        320        330        340        350        360 
PQNGWDTDQF PNSVEELTLA FYEILRHGGF TTGGMNFDAK VRRQSIDPED LFYGHVGAID 

       370        380        390        400        410        420 
VLALALERAA VLVENDRLDA LRRQRYAQWD DAFGRKILAG GYTLESLAAD ALARGVDPQH 

       430        440 
ASGAQERLEN IVNQAIYGLR

« Hide

References

[1]"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen."
Holden M.T.G.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J2315 / LMG 16656.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM747722 Genomic DNA. Translation: CAR57287.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB4ENA5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GenomeReviewsGene locus BceJ2315_66270 in contig AM747722_GR.
KEGGbcj:BCAS0355.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.
ProtClustDBPRK05474.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. Xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_BURCJ
AccessionPrimary (citable) accession number: B4ENA5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: November 16, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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