B4EHL3 (B4EHL3_BURCJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654

Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654

Gene names

Name:	pqqC HAMAP MF_00654 EMBL CAR56223.1
Ordered Locus Names:	BceJ2315_58000
ORF Names:	BCAM2362 EMBL CAR56223.1

Organism

Burkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP] EMBL CAR56223.1

Taxonomic identifier

216591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654
Catalytic activity	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654
Pathway	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654
Sequence similarities	Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
Biological process	PQQ biosynthesis HAMAP MF_00654
Molecular function	Oxidoreductase HAMAP MF_00654 EMBL CAR56223.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrroloquinoline quinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4EHL3 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: EA821E4FA498C593	FASTA	238	27,102
	10 20 30 40 50 60 MNAPISATAL HATPWTATEF EARLRALESR YHIHHPFNRR LNSGACSPAQ IRGWVANRFY 70 80 90 100 110 120 YQICIPLKDA AILSNCPDRD TRRRWIQRLI DHDGQGDNAG GIEAWVRLGE ACGLTRDELW 130 140 150 160 170 180 SLEHVLPGVR FAVDAYVNFA RRAPWQEAVC SSLTEMFAPQ IHLDRLAGWP SHYPWIEPAG 190 200 210 220 230 LHYFRSRVPL AQRDVEHGLA VTLAHFTTPD AQQRALGILQ FKLDILWSML DAVEKAYP

References

[1]	"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen." Holden M.T.G. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM747721 Genomic DNA. Translation: CAR56223.1.
RefSeq	YP_002234963.1. NC_011001.1.
3D structure databases
ProteinModelPortal	B4EHL3.
ModBase	Search...
Protein-protein interaction databases
STRING	B4EHL3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6930613.
GenomeReviews	Gene locus BceJ2315_58000 in contig AM747721_GR.
KEGG	bcj:BCAM2362.
PATRIC	19084084. VBIBurCen118154_6158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG288944.
OMA	DSWPQHY.
ProtClustDB	PRK05157.
Family and domain databases
HAMAP	MF_00654. PQQ_syn_PqqC. [Tree]
InterPro	IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synthPqqC_dom. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KO	K06137.
Pfam	PF03070. TENA_THI-4. 1 hit. [Graphical view]
SUPFAM	SSF48613. Heme_oxygenase. 1 hit.
TIGRFAMs	TIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4EHL3_BURCJ

Accession

Primary (citable) accession number: B4EHL3

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)