B4EE04 (B4EE04_BURCJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361

Gene names

Name:	aroG EMBL CAR53606.1
Ordered Locus Names:	BceJ2315_32220
ORF Names:	BCAL3282 EMBL CAR53606.1

Organism

Burkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]

Taxonomic identifier

216591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361
Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361
Sequence similarities	Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis PIRNR PIRNR001361
Molecular function	Transferase PIRNR PIRNR001361 EMBL CAR53606.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4EE04 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E13560B44E174370	FASTA	357	38,797
	10 20 30 40 50 60 MPPHNTDDVR IRELKELTPP AHLIREFACS EAASELIYHS RQSMHRILHG MDDRLIVVIG 70 80 90 100 110 120 PCSIHDTKAA IEYAGRLVKE RERFKGELEI VMRVYFEKPR TTVGWKGLIN DPHLDNSFKI 130 140 150 160 170 180 NEGLRTAREL LLQINEMGLP AATEYLDMIS PQYIADLISW GAIGARTTES QVHRELASGL 190 200 210 220 230 240 SCPVGFKNGT DGNVKIAVDA IKAASQPHHF LSVTKGGHSA IVSTAGNEDC HVILRGGKAP 250 260 270 280 290 300 NYDADSVNAA CADIGKAGLA ARLMIDASHA NSSKKHENQI PVCADIGRQV AAGDERIVGV 310 320 330 340 350 MIESHLVEGR QDLKEGCALT YGQSITDACI AWDDSVKVLE GLAESVKARR VARGSGN

References

[1]	"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen." Holden M.T.G. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM747720 Genomic DNA. Translation: CAR53606.1.
RefSeq	YP_002232386.1. NC_011000.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4EE04.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6934190.
GenomeReviews	Gene locus BceJ2315_32220 in contig AM747720_GR.
KEGG	bcj:BCAL3282.
PATRIC	19078564. VBIBurCen118154_3405.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG670536.
OMA	MDNSFKL.
ProtClustDB	PRK09261.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006219. DHAP_synth_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01626.
PANTHER	PTHR21225. AroFGH. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
PIRSF	PIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMs	TIGR00034. AroFGH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B4EE04_BURCJ

Accession

Primary (citable) accession number: B4EE04

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)