Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B4EDH7

- PUR5_BURCJ

UniProt

B4EDH7 - PUR5_BURCJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCEN216591:GJI4-3341-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:BceJ2315_32010
ORF Names:BCAL3261
OrganismiBurkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Taxonomic identifieri216591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000001035: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000193003Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi216591.BCAL3261.

Structurei

3D structure databases

ProteinModelPortaliB4EDH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiGEATCEV.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B4EDH7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNPPKSAPDA QGLSYRDAGV DIDAGDALID KIKPFAKKTL RDGVLGGIGG
60 70 80 90 100
FGALFEVPKK YKEPVLVSGT DGVGTKLKLA FHLNKHDTVG QDLVAMSVND
110 120 130 140 150
ILVQGAEPLF FLDYFACGKL DVDTAATVVK GIAQGCELSG CALIGGETAE
160 170 180 190 200
MPGMYPDGEY DLAGFAVGAV EKSKIIDGST IAEGDVVLGL ASSGIHSNGF
210 220 230 240 250
SLVRKIIERA NPDLSADFHG RSLADALMAP TRIYVKPLLA LMQKLSVKGM
260 270 280 290 300
AHITGGGLVE NIPRVLREGL TAELDQNAWP LPPLFKWLQE HGGVADAEMH
310 320 330 340 350
RVFNCGIGMA VIVSAADADA AIADLTAAGE QVWKIGTVRA TREGEAQTVV

V
Length:351
Mass (Da):36,793
Last modified:September 23, 2008 - v1
Checksum:i757E04B44FB0AA84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR53585.1.
RefSeqiYP_002232365.1. NC_011000.1.

Genome annotation databases

EnsemblBacteriaiCAR53585; CAR53585; BCAL3261.
GeneIDi6933106.
KEGGibcj:BCAL3261.
PATRICi19078520. VBIBurCen118154_3383.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR53585.1 .
RefSeqi YP_002232365.1. NC_011000.1.

3D structure databases

ProteinModelPortali B4EDH7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 216591.BCAL3261.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR53585 ; CAR53585 ; BCAL3261 .
GeneIDi 6933106.
KEGGi bcj:BCAL3261.
PATRICi 19078520. VBIBurCen118154_3383.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi GEATCEV.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci BCEN216591:GJI4-3341-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610.

Entry informationi

Entry nameiPUR5_BURCJ
AccessioniPrimary (citable) accession number: B4EDH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3