B4EDD8 (B4EDD8_BURCJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL CAR53545.1

Gene names

Name:	wcbS EMBL CAR53545.1
Ordered Locus Names:	BceJ2315_31660
ORF Names:	BCAL3219 EMBL CAR53545.1

Organism

Burkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]

Taxonomic identifier

216591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4EDD8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E720546D3B8E4193	FASTA	305	33,072
	10 20 30 40 50 60 MSAPSGWATR QGTLARPLAI DGHGLHTGRR VGVRILPGRP EEGVTGIAFR RVAQGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGVGVRTIEH LLASLLACEI DHAIVEIDAE EVPILDGSAA 130 140 150 160 170 180 PWVDAIRACG RVALDAPKRF IRVLRPVVVT DGEGDQRREM RIEPAPRYEL SVRNDLRGFG 190 200 210 220 230 240 DMHWDGALTP AAFATEIAPS RSYGRVKWAV PAIVAGYLRG VPILRGARPS CTASIVGNRV 250 260 270 280 290 300 LGGMRLPEEF VRHRVLDLVG DLALAGAPLL ARVSALRPSH EMNFRLVDAL LAESDAWQWA EFPDA

References

[1]	"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen." Holden M.T.G. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM747720 Genomic DNA. Translation: CAR53545.1.
RefSeq	YP_002232330.1. NC_011000.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B4EDD8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6934256.
GenomeReviews	Gene locus BceJ2315_31660 in contig AM747720_GR.
KEGG	bcj:BCAL3219.
PATRIC	19078442. VBIBurCen118154_3344.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG482342.
OMA	IAFRRVA.
ProtClustDB	PRK13187.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

B4EDD8_BURCJ

Accession

Primary (citable) accession number: B4EDD8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)