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B4EB42 (AROA_BURCJ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:BceJ2315_28880
ORF Names:BCAL2952
OrganismBurkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]
Taxonomic identifier216591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4344343-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099671

Sequences

Sequence LengthMass (Da)Tools
B4EB42 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 42EC5FEAC9D4977D

FASTA43446,290
        10         20         30         40         50         60 
MDYLDLGPYS SASGTVRLPG SKSISNRVLL LAALAEGETT ITNLLDSDDT RVMLDALGKL 

        70         80         90        100        110        120 
GVKLARDGDT CVVTGTRGAF TAKTADLFLG NAGTAVRPLT AALAVNGGDY RVHGVPRMHE 

       130        140        150        160        170        180 
RPIGDLVDGL RQIGAQIDYE LNEGYPPLRI KPATISVDAP IRVRGDVSSQ FLTALLMTLP 

       190        200        210        220        230        240 
LVKAKDGRTV VEVDGELISK PYIDITIRLM ARFGVTVERD GWQRFVVPAG VRYRSPGRIM 

       250        260        270        280        290        300 
VEGDASSASY FLAAGALGGG PLRVEGVGRA SIQGDVGFAN ALMQMGANVT MGDDWIDVRG 

       310        320        330        340        350        360 
IGHDHGKLEP IDMDFNLIPD AAMTIAVAAL FANGTSTLRN IASWRVKETD RIAAMATELR 

       370        380        390        400        410        420 
KVGAIVEEGP DYLVVTPPAK LTPNAAIDTY DDHRMAMCFS LVSLGGVPVR INDPKCVGKT 

       430 
FPDYFDRFAA LAKA

« Hide

References

[1]"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen."
Holden M.T.G.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J2315 / LMG 16656.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM747720 Genomic DNA. Translation: CAR53255.1.
RefSeqYP_002232052.1. NC_011000.1.

3D structure databases

ProteinModelPortalB4EB42.
ModBaseSearch...

Protein-protein interaction databases

STRINGB4EB42.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6933442.
GenomeReviewsGene locus BceJ2315_28880 in contig AM747720_GR.
KEGGbcj:BCAL2952.
PATRIC19077860. VBIBurCen118154_3060.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAGADIEWG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_BURCJ
AccessionPrimary (citable) accession number: B4EB42
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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