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B4EAU4 (B4EAU4_BURCJ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length247 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding14 – 152NADP
Nucleotide binding35 – 384NADP
Nucleotide binding61 – 622NADP
Nucleotide binding88 – 903NADP
Nucleotide binding186 – 1883NADP
Region35 – 384Chloride binding PDB 4K6C

Sites

Binding site101NADP; via carbonyl oxygen
Binding site1531NADP
Binding site1571NADP

Sequences

Sequence LengthMass (Da)Tools
B4EAU4 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: B9F04F0E7FF1FE83

FASTA24726,383
        10         20         30         40         50         60 
MTKRIAVVTG GMGGLGEAVS IRLNDAGHRV VVTYSPNNTG ADRWLTEMHA AGREFHAYPV 

        70         80         90        100        110        120 
DVADHDSCQQ CIEKIVRDVG PVDILVNNAG ITRDMTLRKL DKVNWDAVIR TNLDSVFNMT 

       130        140        150        160        170        180 
KPVCDGMVER GWGRIVNISS VNGSKGSVGQ TNYAAAKAGM HGFTKSLALE IARKGVTVNT 

       190        200        210        220        230        240 
VSPGYLATKM VTAIPQDILD TKILPQIPAG RLGKPEEVAA LVAYLCSEEA GFVTGSNIAI 


NGGQHMH 

« Hide

References

« Hide 'large scale' references
[1]"The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients."
Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D., Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S., Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K., Scott P., Walker D. expand/collapse author list , White B., Rose H., Iversen P., Mil-Homens D., Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R., Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.
J. Bacteriol. 191:261-277(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610.
[2]"X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP."
Fairman J.W., Edwards T.E., Lorimer D.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH NADP.
[3]"X-ray crystal structure of a putative Acetoacyl-CoA reductase from Burkholderia cenocepacia."
Fairman J.W., Edwards T.E., Lorimer D.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH CHLORIDE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM747720 Genomic DNA. Translation: CAR51139.1.
RefSeqYP_002229987.1. NC_011000.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4K6CX-ray1.85A/B1-247[»]
4K6FX-ray1.50A/B/C/D1-247[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING216591.BCAL0833.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR51139; CAR51139; BCAL0833.
GeneID6933950.
KEGGbcj:BCAL0833.
PATRIC19073398. VBIBurCen118154_0874.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1028.
KOK00023.
OMAAICIKLA.
OrthoDBEOG6N3CR8.

Enzyme and pathway databases

BioCycBCEN216591:GJI4-858-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR011283. Acetoacetyl-CoA_reductase.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsTIGR01829. AcAcCoA_reduct. 1 hit.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB4EAU4_BURCJ
AccessionPrimary (citable) accession number: B4EAU4
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)