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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCEN216591:GJI4-707-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BceJ2315_06730
ORF Names:BCAL0679
OrganismiBurkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Taxonomic identifieri216591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000001035 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 593593Arginine--tRNA ligasePRO_1000095342Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi216591.BCAL0679.

Structurei

3D structure databases

ProteinModelPortaliB4E9M9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi138 – 14811"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiHVGHIRN.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E9M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPAHKQTLE ALLADSVKQV AHALKGADAA FVAPAITLER PKVAAHGDVA
60 70 80 90 100
CNVAMQLAKP LGTNPRQLAE QIVAALTAQP AAQGLVEAAE IAGPGFINLR
110 120 130 140 150
LSAAAKQAVI AAVFDQGRAF GTSDREKGKQ VLLEFVSANP TGPLHVGHGR
160 170 180 190 200
QAALGDVLAN VIASQGYAVH REFYYNDAGV QIGNLAISTQ ARARGLKPGD
210 220 230 240 250
AGWPEAAYNG EYIADIARDY LNGETVAASD GEPVKGTGDV EDLDAIRKFA
260 270 280 290 300
VTYLRREQDM DLQAFGVKFD QYYLESSLYS EGRVEKTVDA LVKAGMTYEQ
310 320 330 340 350
DGALWLRTTD EGDDKDRVMR KSDGTYTYFV PDVAYHVTKW ERGFTKVINI
360 370 380 390 400
QGSDHHGTIA RVRAGLQGLH IGIPKGYPDY VLHKMVTVMR DGQEVKISKR
410 420 430 440 450
AGSYVTVRDL IEWSGGAAAG QEAAPDLIDE ATITRGRDAV RFFLISRKAD
460 470 480 490 500
TEFVFDIDLA LKQNDENPVY YVQYAHARIC SVLNELKSRY NVDVAQLPGA
510 520 530 540 550
DLSQLTSAQA TSLMQKLAEY PDMLTHAANE LAPHAVAFYL RDLAGEFHSF
560 570 580 590
YNAERVLVDD AAPRNARAAL LAATRQVLEN GLAMLGVSAP AKM
Length:593
Mass (Da):64,232
Last modified:September 23, 2008 - v1
Checksum:i56B5DA949E9A5413
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR50988.1.
RefSeqiWP_006489096.1. NC_011000.1.

Genome annotation databases

EnsemblBacteriaiCAR50988; CAR50988; BCAL0679.
GeneIDi6931133.
KEGGibcj:BCAL0679.
PATRICi19073071. VBIBurCen118154_0712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR50988.1.
RefSeqiWP_006489096.1. NC_011000.1.

3D structure databases

ProteinModelPortaliB4E9M9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216591.BCAL0679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR50988; CAR50988; BCAL0679.
GeneIDi6931133.
KEGGibcj:BCAL0679.
PATRICi19073071. VBIBurCen118154_0712.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiHVGHIRN.
OrthoDBiEOG6JB13C.

Enzyme and pathway databases

BioCyciBCEN216591:GJI4-707-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610.

Entry informationi

Entry nameiSYR_BURCJ
AccessioniPrimary (citable) accession number: B4E9M9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 23, 2008
Last modified: July 22, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.