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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei199 – 1991UniRule annotation
Active sitei641 – 6411UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciBCEN216591:GJI4-2686-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
ORF Names:BCAL2631Imported
OrganismiBurkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315))Imported
Taxonomic identifieri216591 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000001035 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216591.BCAL2631.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E8C5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPDAPTGT LATAANGRAK TATKPKDPIH QTKPATKAAG APARKAVAPK
60 70 80 90 100
AGTRTRDDKD GPLFEDIRFL GRLLGDVVRE QEGDTVFDVV ETIRQTAVKF
110 120 130 140 150
RREDDSEAAQ TLEKKLRKLT PEQTVSVVRA FSYFSHLANI AEDRHHNRRR
160 170 180 190 200
RIHALAGSAP QPGTVAYALD QLKTTGNASK RLLQRFFDDA LIVPVLTAHP
210 220 230 240 250
TEVQRKSILD AQHDIARLLA ERDQELTARE RQYNEAMLRA RVTALWQTRM
260 270 280 290 300
LRDSRLTVGD EIENALSYYR ATFLDELPAL YGDIEAALAE HGLSARVPAF
310 320 330 340 350
FQMGSWIGGD RDGNPNVTAA TLDEAINRQA AVILEHYLEQ VHKLGAELSV
360 370 380 390 400
SNLLVGANDA VKALAAASPD QSPHRVDEPY RRALIGIYTR LAASARVRLG
410 420 430 440 450
EGTVPVRSAG RGAPPVRAIP YEDSEAFVAD LKVLTASLDE HHGASLAAPR
460 470 480 490 500
LAPLVRAAEV FGFHLASIDL RQSSDIHEAV VAELFARAGV EADYAALAEE
510 520 530 540 550
DKLRVLLAAL ADPRPLRSPY LEYSALAQSE LGVFEKAREV RTQFGARAVR
560 570 580 590 600
NYIISHTETV SDLVEVLLLQ KETGLLEGTL GVPGRDAKNS LMVIPLFETI
610 620 630 640 650
PDLRDASRIM RDYFALPGID ALIAHQGAEQ EVMLGYSDSN KDGGFLTSNW
660 670 680 690 700
ELYRAELALV DLFRERKITL RLFHGRGGTV GRGGGPTYQA ILSQPPGTVN
710 720 730 740 750
GQIRLTEQGE VIASKFSNPS IGRRNLETVV AATLEASLLP QSNAPAQLPA
760 770 780 790 800
FEAAMQTLSD SAMAAYRALV YETPGFTDYF FSSTPITEIA ELNIGSRPAS
810 820 830 840 850
RKLQDPKQRK IEDLRAIPWG FSWGQCRLLL TGWYGFGSAV SAYLDGAPDA
860 870 880 890 900
AERTKRVTLL KKMNKTWPFF SNLLSNMDMV LAKTDLAVAS RYAQLVSDRK
910 920 930 940 950
LRKHVFERIV AEWERTSQAL AEITGHEGRL ATNPLLARSI KNRFPYLDPL
960 970 980
NHLQVELIKR HRAGDTNARL RRGIHLTING IAAGLRNTG
Length:989
Mass (Da):108,725
Last modified:September 23, 2008 - v1
Checksum:i370D3D999DCE0012
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR52933.1.

Genome annotation databases

EnsemblBacteriaiCAR52933; CAR52933; BCAL2631.
KEGGibcj:BCAL2631.
PATRICi19077175. VBIBurCen118154_2723.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM747720 Genomic DNA. Translation: CAR52933.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216591.BCAL2631.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR52933; CAR52933; BCAL2631.
KEGGibcj:BCAL2631.
PATRICi19077175. VBIBurCen118154_2723.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciBCEN216591:GJI4-2686-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610Imported.

Entry informationi

Entry nameiB4E8C5_BURCJ
AccessioniPrimary (citable) accession number: B4E8C5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 22, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.