B4E701 (B4E701_BURCJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inositol 2-dehydrogenase HAMAP MF_01671
EC=1.1.1.18 HAMAP MF_01671

Alternative name(s):
Myo-inositol 2-dehydrogenase HAMAP MF_01671

Gene names

Name:	idh EMBL CAR51734.1
Synonyms:	iolG HAMAP MF_01671
Ordered Locus Names:	BceJ2315_14020
ORF Names:	BCAL1435 EMBL CAR51734.1

Organism

Burkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]

Taxonomic identifier

216591 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP MF_01671
Catalytic activity	Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. SAAS SAAS000683 HAMAP MF_01671
Subunit structure	Homotetramer By similarity. HAMAP MF_01671 SAAS SAAS000683
Sequence similarities	Belongs to the gfo/idh/mocA family. HAMAP MF_01671

Ontologies

Keywords
Ligand	NAD SAAS SAAS000683 HAMAP MF_01671
Molecular function	Oxidoreductase SAAS SAAS000683 HAMAP MF_01671 EMBL CAR51734.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	inositol 2-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4E701 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: D07354B76A87B9EA	FASTA	337	36,591
	10 20 30 40 50 60 MTLQIGVIGC GAIGQDHIRR LTRTLSGARV VAVNDIDPQQ ARDAVTKYGL DAEIYGDGHE 70 80 90 100 110 120 VVAAADVQAV LVTSWGPTHE AFVLDAIAHG KPVFCEKPLA VTADGCMRIV EAEVAHGKRL 130 140 150 160 170 180 VQVGFMRPYD EGYRALKRVI DSGQIGAPLM LHCAHRNQSV GERYTTDMAI TDTLIHELDV 190 200 210 220 230 240 LRWLLGEDYT SAQVVYPKKT RHASAHLADP QIVLLETASG VRIDVEIFVN CQYGYDIQCE 250 260 270 280 290 300 VVGEQGIAKL PDPPAVGLRH AARQSVEIMT DWKERFIASY DVELQAFIDG VRQGALTGPS 310 320 330 AWDGYAAAVA ADACVRAQQS GAVEPIAMAE RPAFYRG

References

[1]	"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen." Holden M.T.G. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM747720 Genomic DNA. Translation: CAR51734.1.
RefSeq	YP_002230566.1. NC_011000.1.
3D structure databases
ProteinModelPortal	B4E701.
ModBase	Search...
Protein-protein interaction databases
STRING	B4E701.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6931734.
GenomeReviews	Gene locus BceJ2315_14020 in contig AM747720_GR.
KEGG	bcj:BCAL1435.
PATRIC	19074649. VBIBurCen118154_1491.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG612336.
OMA	YDVELQD.
ProtClustDB	CLSK896889.
Family and domain databases
HAMAP	MF_01671. IolG. [Tree]
InterPro	IPR023794. MI/DCI_dehydrogenase. IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR004104. OxRdtase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00010.
PANTHER	PTHR22604:SF7. PTHR22604:SF7. 1 hit.
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF02894. GFO_IDH_MocA_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B4E701_BURCJ

Accession

Primary (citable) accession number: B4E701

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)