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Reviewed, UniProtKB/Swiss-Prot B4E5R8 (HEM6_BURCJ)

Last modified November 3, 2009. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: BceJ2315_23500
ORF Names: BCAL2390
OrganismBurkholderia cepacia (strain J2315 / LMG 16656) (Burkholderia cenocepacia (strain J2315)) [Complete proteome] [HAMAP]
Taxonomic identifier216591 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

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Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Coproporphyrinogen-III oxidase, aerobic HAMAP MF_00333
PRO_1000119792

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Sequences

Sequence LengthMass (Da)Tools
B4E5R8-1 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: F9EEB7ABEDD7BB8D

FASTA30734,626
        10         20         30         40         50         60 
MTDSTYDVAR VRTYLQGLQT RIADALGALD GTPLATDTWQ RGPAERLRGG GCTRILEGGR 

        70         80         90        100        110        120 
VFERAGIGFS DVAGDALPPS ASAARPQLAG RGFEALGVSL VLHPRNPYCP TVHMNVRMLI 

       130        140        150        160        170        180 
ATKPGEAPVF WFGGGMDLTP VYGFEDDARH FHQTCKDALD PFGIELYPRF KQWCDEYFFL 

       190        200        210        220        230        240 
KHRNETRGIG GIFFDDFSEP GFERSFDLMQ SVGDAFLHAY LPIVERRAEL PYGERERDFQ 

       250        260        270        280        290        300 
AYRRGRYVEF NLVFDRGTLF GLQSGGRTES ILMSMPPVAN WRYNWQPEPG SAEARLYSDF 


LVPRDWV

« Hide

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References

[1]"Genomic analysis of Burkholderia cenocepacia J2315, an epidemic cystic fibrosis pathogen."
Holden M.T.G.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

AM747720 Genomic DNA. Translation: CAR52691.1.
RefSeqYP_002231514.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID6934001.
GenomeReviewsGene locus BceJ2315_23500 in contig AM747720_GR.
KEGGbcj:BCAL2390.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVKAYLLD.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_BURCJ
AccessionPrimary (citable) accession number: B4E5R8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 23, 2008
Last modified: November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents