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Protein
Submitted name:

cDNA FLJ61580, highly similar to Calsyntenin-1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ61580, highly similar to Calsyntenin-1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei841 – 86121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 962934Sequence analysisPRO_5002804102Add
BLAST

Proteomic databases

PaxDbiB4E3Q1.

Expressioni

Gene expression databases

BgeeiB4E3Q1.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366513.

Structurei

3D structure databases

ProteinModelPortaliB4E3Q1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 164127CadherinInterPro annotationAdd
BLAST
Domaini165 – 265101CadherinInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili896 – 92328Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1834. Eukaryota.
ENOG410XT2J. LUCA.
HOGENOMiHOG000037537.
HOVERGENiHBG051146.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.60.40.60. 2 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR026914. Calsyntenin.
IPR013320. ConA-like_dom.
[Graphical view]
PANTHERiPTHR14139. PTHR14139. 1 hit.
PfamiPF00028. Cadherin. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 2 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50268. CADHERIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E3Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRPAPALA PAARLLLAGL LCGGGVWAAR VNKHKPWLEP TYHGIVTEND
60 70 80 90 100
NTVLLDPPLI ALDKDAPLRF AESFEVTVTK EGEICGFKIH GQNVPFDAVV
110 120 130 140 150
VDKSTGEGVI RSKEKLDCEL QKDYSFTIQA YDCGKGPDGT NVKKSHKATV
160 170 180 190 200
HIQVNDVNEY APVFKEKSYK ATVIEGKQYD SILRVEAVDA DCSPQFSQIC
210 220 230 240 250
SYEIITPDVP FTVDKDGYIK NTEKLNYGKE HQYKLTVTAY DCGKKRATED
260 270 280 290 300
VLVKISIKPT CTPGWQGWNN RIEYEPGTGA LAVFPNIHLE TCDEPVASVQ
310 320 330 340 350
ATVELETSHI GKGCDRDTYS EKSLHRLCGA AAGTAELLPS PSGSLNWTMG
360 370 380 390 400
LPTDNGHDSD QVFEFNGTQA VRIPDGVVSV SPKEPFTISV WMRHGPFGRK
410 420 430 440 450
KETILCSSDK TDMNRHHYSL YVHGCRLIFL FRQDPSEEKK YRPAEFHWKL
460 470 480 490 500
NQVCDEEWHH YVLNVEFPSV TLYVDGTSHE PFSVTEDYPL HPSKIETQLV
510 520 530 540 550
VGACWQGGDL HMTQFFRGNL AGLTLRSGKL ADKKVIDCLY TCKEGLDLQV
560 570 580 590 600
LEDSGRGVQI QAHPSQLVLT LEGEDLGELD KAMQHISYLN SRQFPTPGIR
610 620 630 640 650
RLKITSTIKC FNEATCISVP PVDGYVMVLQ PEEPKISLSG VHHFARAASE
660 670 680 690 700
FESSEGVFLF PELRIISTIT REVEPEGDGA EDPTVQESLV SEEIVHDLDT
710 720 730 740 750
CEVTVEGEEL NHEQESLEVD MARLQQKGIE VSSSELGMTF TGVDTMASYE
760 770 780 790 800
EVLHLLRYRN WHARSLLDRK FKLICSELNG RYISNEFKVE VNVIHTANPM
810 820 830 840 850
EHANHMAAQP QFVHPEHRSF VDLSGHNLAN PHPFAVVPST ATVVIVVCVS
860 870 880 890 900
FLVFMIILGV FRIRAAHRRT MRDQDTGKEN EMDWDDSALT ITVNPMETYE
910 920 930 940 950
DQHSSEEEEE EEEEEESEDG EEEDDITSAE SESSEEEEGE QGDPQNATRQ
960
QQLEWDDSTL SY
Length:962
Mass (Da):107,816
Last modified:September 23, 2008 - v1
Checksum:i7BF0D0D723696E0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304813 mRNA. Translation: BAG65563.1.
RefSeqiNP_001289812.1. NM_001302883.1.
UniGeneiHs.29665.

Genome annotation databases

GeneIDi22883.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304813 mRNA. Translation: BAG65563.1.
RefSeqiNP_001289812.1. NM_001302883.1.
UniGeneiHs.29665.

3D structure databases

ProteinModelPortaliB4E3Q1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366513.

Proteomic databases

PaxDbiB4E3Q1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22883.

Organism-specific databases

CTDi22883.

Phylogenomic databases

eggNOGiKOG1834. Eukaryota.
ENOG410XT2J. LUCA.
HOGENOMiHOG000037537.
HOVERGENiHBG051146.

Miscellaneous databases

ChiTaRSiCLSTN1. human.
GenomeRNAii22883.

Gene expression databases

BgeeiB4E3Q1.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.60.40.60. 2 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR026914. Calsyntenin.
IPR013320. ConA-like_dom.
[Graphical view]
PANTHERiPTHR14139. PTHR14139. 1 hit.
PfamiPF00028. Cadherin. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 2 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50268. CADHERIN_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: UterusImported.

Entry informationi

Entry nameiB4E3Q1_HUMAN
AccessioniPrimary (citable) accession number: B4E3Q1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 8, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.