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Protein
Submitted name:

cDNA FLJ52848, highly similar to ATP-dependent RNA helicase DDX3X (EC 3.6.1.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. helicase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

HelicaseImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52848, highly similar to ATP-dependent RNA helicase DDX3X (EC 3.6.1.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Structurei

3D structure databases

ProteinModelPortaliB4E3C4.
SMRiB4E3C4. Positions 183-277.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000203858.
HOVERGENiHBG015893.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51195. Q_MOTIF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E3C4-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MRESRLISDL GGFAGVRSAA GRDWRPFWLG GLRPSRLAQP GFPSGGPGGT
60 70 80 90 100
RCLRACEQGF AGLDLNSSDN QSGGSTASKG RYIPPHLRNR EATKGFYDKD
110 120 130 140 150
SSGWSSSKDK DAYSSFGSRS DSRGKSSFFS DRGSGSRGRF DDRGRSDYDG
160 170 180 190 200
IGSRGDRSGF GKFERGGNSR WCDKSDEDDW SKPLPPSERL EQELFSGGNT
210 220 230 240 250
GINFEKYDDI PVEATGNNCP PHIESFSDVE MGEIIMGNIE LTRYTRPTPV
260 270 280 290 300
QKHAIPIIKE KRDLMACAQT GKWKVWAPQT IPNLLGISTN ERVGSTDLRG

SQKIFIPI
Length:308
Mass (Da):33,792
Last modified:September 23, 2008 - v1
Checksum:iF696BDC01A5743C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304661 mRNA. Translation: BAG65436.1.
UniGeneiHs.743263.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304661 mRNA. Translation: BAG65436.1.
UniGeneiHs.743263.

3D structure databases

ProteinModelPortaliB4E3C4.
SMRiB4E3C4. Positions 183-277.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000203858.
HOVERGENiHBG015893.

Miscellaneous databases

ChiTaRSiDDX3X. human.
NextBioi35477502.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: UterusImported.

Entry informationi

Entry nameiB4E3C4_HUMAN
AccessioniPrimary (citable) accession number: B4E3C4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 26, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.