B4E2X3 (B4E2X3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methyltransferase-like protein 13 Ensembl ENSP00000401955

Submitted name:
cDNA FLJ56024 EMBL BAG65285.1

Gene names

Name:

METTL13 Ensembl ENSP00000401955

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAG65285.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	698 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	methylation Inferred from electronic annotation. Source: GOC
Molecular_function	methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4E2X3 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: E7122FFB3DE35D9F	FASTA	698	78,688
	10 20 30 40 50 60 MRAFVVSREF GSVDYWEKFF QQRGKKAFEW YGTYLELCGV LHKYIKPREK VLVIGCGNSE 70 80 90 100 110 120 LSEQLYDVGY RDIVNIDISE VVIKQMKECN ATRRPQMSFL KMDMTQMEFP DASFQVVLDK 130 140 150 160 170 180 GTLDAVLTDE EEKTLQQVDR MLAEVGRVLQ VGGRYLCISL AQAHILKKAV GHFSREGWMV 190 200 210 220 230 240 RVHQVANSQD QVLEAEPQFS LPVFAFIMTK FRPVPGSALQ IFELCAQEQR KPVRLESAER 250 260 270 280 290 300 LAEAVQERQQ YAWLCSQLRR KARLGSVSLD LCDGDTGEPR YTLHVVDSPT VKPSRDNHFA 310 320 330 340 350 360 IFIIPQGRET EWLFGMDEGR KQLAASAGFR RLITVALHRG QQYESMDHIQ AELSARVMEL 370 380 390 400 410 420 APAGMPTQQQ VPFLSVGGDI GVRTVQHQDC SPLSGDYVIE DVQGDDKRYF RRLIFLSNRN 430 440 450 460 470 480 VVQSEARLLK DVSHKAQKKR KKDRKKQRPA DAEDLPAAPG QSIDKSYLCC EHHKAMIAGL 490 500 510 520 530 540 ALLRNPELLL EIPLALLVVG LGGGSLPLFV HDHFPKSCID AVEIDPSMLE VATQWFGFSQ 550 560 570 580 590 600 SDRMKVHIAD GLDYIASLAG GGEARPCYDV IMFDVDSKDP TLGMSCPPPA FVEQSFLQKV 610 620 630 640 650 660 KSILTPEGVF ILNLVCRDLG LKDSVLAGLK AVFPLLYVRR IEGEVNEILF CQLHPEQKLA 670 680 690 TPELLETAQA LERTLRKPGR GWDDTYVLSD MLKTVKIV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Uterus EMBL BAG65285.1.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL031864 Genomic DNA. No translation available. AK304471 mRNA. Translation: BAG65285.1.
IPI	IPI00942442.
UniGene	Hs.494705.
3D structure databases
SMR	B4E2X3. Positions 8-215, 473-609.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000458517; ENSP00000401955; ENSG00000010165.
UCSC	uc010pml.2. human.
Organism-specific databases
HGNC	HGNC:24248. METTL13.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000006675.
HOVERGEN	HBG104193.
Gene expression databases
ArrayExpress	B4E2X3.
Family and domain databases
InterPro	IPR013216. Methyltransf_11. [Graphical view]
Pfam	PF08241. Methyltransf_11. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35477391.

Entry information

Entry name

B4E2X3_HUMAN

Accession

Primary (citable) accession number: B4E2X3

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.