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B4E2X3 (B4E2X3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

cDNA FLJ56024 EMBL BAG65285.1
Gene names
Name:METTL13 Ensembl ENSP00000401955
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAG65285.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length698 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmethylation

Inferred from electronic annotation. Source: GOC

   Molecular_functionmethyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B4E2X3 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: E7122FFB3DE35D9F

FASTA69878,688
        10         20         30         40         50         60 
MRAFVVSREF GSVDYWEKFF QQRGKKAFEW YGTYLELCGV LHKYIKPREK VLVIGCGNSE 

        70         80         90        100        110        120 
LSEQLYDVGY RDIVNIDISE VVIKQMKECN ATRRPQMSFL KMDMTQMEFP DASFQVVLDK 

       130        140        150        160        170        180 
GTLDAVLTDE EEKTLQQVDR MLAEVGRVLQ VGGRYLCISL AQAHILKKAV GHFSREGWMV 

       190        200        210        220        230        240 
RVHQVANSQD QVLEAEPQFS LPVFAFIMTK FRPVPGSALQ IFELCAQEQR KPVRLESAER 

       250        260        270        280        290        300 
LAEAVQERQQ YAWLCSQLRR KARLGSVSLD LCDGDTGEPR YTLHVVDSPT VKPSRDNHFA 

       310        320        330        340        350        360 
IFIIPQGRET EWLFGMDEGR KQLAASAGFR RLITVALHRG QQYESMDHIQ AELSARVMEL 

       370        380        390        400        410        420 
APAGMPTQQQ VPFLSVGGDI GVRTVQHQDC SPLSGDYVIE DVQGDDKRYF RRLIFLSNRN 

       430        440        450        460        470        480 
VVQSEARLLK DVSHKAQKKR KKDRKKQRPA DAEDLPAAPG QSIDKSYLCC EHHKAMIAGL 

       490        500        510        520        530        540 
ALLRNPELLL EIPLALLVVG LGGGSLPLFV HDHFPKSCID AVEIDPSMLE VATQWFGFSQ 

       550        560        570        580        590        600 
SDRMKVHIAD GLDYIASLAG GGEARPCYDV IMFDVDSKDP TLGMSCPPPA FVEQSFLQKV 

       610        620        630        640        650        660 
KSILTPEGVF ILNLVCRDLG LKDSVLAGLK AVFPLLYVRR IEGEVNEILF CQLHPEQKLA 

       670        680        690 
TPELLETAQA LERTLRKPGR GWDDTYVLSD MLKTVKIV 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Uterus EMBL BAG65285.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL031864 Genomic DNA. No translation available.
AK304471 mRNA. Translation: BAG65285.1.
RefSeqXP_005245312.1. XM_005245255.1.
UniGeneHs.494705.

3D structure databases

ProteinModelPortalB4E2X3.
SMRB4E2X3. Positions 8-215, 473-609.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEB4E2X3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000458517; ENSP00000401955; ENSG00000010165.
GeneID51603.
KEGGhsa:51603.
UCSCuc010pml.2. human.

Organism-specific databases

CTD51603.
HGNCHGNC:24248. METTL13.
GenAtlasSearch...

Phylogenomic databases

HOGENOMHOG000006675.
HOVERGENHBG104193.

Gene expression databases

ArrayExpressB4E2X3.

Family and domain databases

InterProIPR013216. Methyltransf_11.
[Graphical view]
PfamPF08241. Methyltransf_11. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35477391.

Entry information

Entry nameB4E2X3_HUMAN
AccessionPrimary (citable) accession number: B4E2X3
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 19, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.