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B4E2K6 (B4E2K6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL BAG65168.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1278 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PDZ (DHR) domain. RuleBase RU003354

Contains 1 PH domain.

Contains DH (DBL-homology) domain. SAAS SAAS001331

Contains PH domain. SAAS SAAS000219

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue12781 EMBL BAG65168.1

Sequences

Sequence LengthMass (Da)Tools
B4E2K6 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: A6279845201B370A

FASTA1,278143,947
        10         20         30         40         50         60 
MSGTQSTITD RFPLKKPIRH GSILNRESPT DKKQKVERIA SHDFDPTGLV QRCVIIQKDD 

        70         80         90        100        110        120 
NGFGLTVSGD NPVFVQSVKE DGAAMRAGVQ TGDRIIKVNG TLVTHSNHLE VVKLIKSGSY 

       130        140        150        160        170        180 
VALTVQGRPP GSPQIPLADS EVEPSVIGHM SPIMTSPHSP GASGNMERIT SPVLMGEENN 

       190        200        210        220        230        240 
VVHNQKVEIL RKMLQKEQER LQLLQEDYNR TPAQRLLKEI QEAKKHIPQL QEQLSKATGS 

       250        260        270        280        290        300 
AQDGAVVTPS RPLGDTLTVS EAETDPGDVL GRTDCSSGDA SRPSSDNADS PKSGPKERIY 

       310        320        330        340        350        360 
LEENPEKSET IQDTDTQSLV GSPSTRIAPH IIGAEDDDFG TEHEQINGQC SCFQSIELLK 

       370        380        390        400        410        420 
SRPAHLAVFL HHVVSQFDPA TLLCYLYSDL YKHTNSKETR RIFLEFHQFF LDRSAHLKVS 

       430        440        450        460        470        480 
VPDEMSADLE KRRPELIPED LHRHYIQTMQ ERVHPEVQRH LEDFRQKRSM GLTLAESELT 

       490        500        510        520        530        540 
KLDAERDKDR LTLEKERTCA EQIVAKIEEV LMTAQAVEED KSSTMQYVIL MYMKHLGVKV 

       550        560        570        580        590        600 
KEPRNLEHKR GRIGFLPKIK QSMKKDKEGE EKGKRRGFPS ILGPPRRPSR HDNSAIGRAM 

       610        620        630        640        650        660 
ELQKARHPKH LSTPSSVSPE PQDSAKLRQS GLANEGTDAG YLPANSMSSV ASGASFSQEG 

       670        680        690        700        710        720 
GKENDTGSKQ VGETSAPGDT LDGTPRTLNT VFDFPPPPLD QVQEEECEVE RVTEHGTPKP 

       730        740        750        760        770        780 
FRKFDSVAFG ESQSEDEQFE NDLETDPPNW QQLVSREVLL GLKPCEIKRQ EVINELFYTE 

       790        800        810        820        830        840 
RAHVRTLKVL DQVFYQRVSR EGILSPSELR KIFSNLEDIL QLHIGLNEQM KAVRKRNETS 

       850        860        870        880        890        900 
VIDQIGEDLL TWFSGPGEEK LKHAAATFCS NQPFALEMIK SRQKKDSRFQ TFVQDAESNP 

       910        920        930        940        950        960 
LCRRLQLKDI IPTQMQRLTK YPLLLDNIAK YTEWPTEREK VKKAADHCRQ ILNYVNQAVK 

       970        980        990       1000       1010       1020 
EAENKQRLED YQRRLDTSSL KLSEYPNVEE LRNLDLTKRK MIHEGPLVWK VNRDKTIDLY 

      1030       1040       1050       1060       1070       1080 
TLLLEDILVL LQKQDDRLVL RCHSKILAST ADSKHTFSPV IKLSTVLVRQ VATDNKALFV 

      1090       1100       1110       1120       1130       1140 
ISMSDNGAQI YELVAQTVSE KTVWQDLICR MAASVKEQST KPIPLPQSTP GEGDNDEEDP 

      1150       1160       1170       1180       1190       1200 
SKLKEEQHGI SVTGLQSPDR DLGLESTLIS SKPQSHSLST SGKSEVRDLF VAERQFAKEQ 

      1210       1220       1230       1240       1250       1260 
HTDGTLKEVG EDYQIAIPDS HLPVSEERWA LDALRNLGLL KQLLVQQLGL TEKSVQEDWQ 

      1270 
HFPRYRTASQ GPQTDSVI 

« Hide

References

[1]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Trachea EMBL BAG65168.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK304316 mRNA. Translation: BAG65168.1.
RefSeqNP_001185594.1. NM_001198665.1.
NP_056128.1. NM_015313.2.
UniGeneHs.24598.

3D structure databases

ProteinModelPortalB4E2K6.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEB4E2K6.

Protocols and materials databases

DNASU23365.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID23365.
KEGGhsa:23365.

Organism-specific databases

CTD23365.

Phylogenomic databases

HOGENOMHOG000034046.
HOVERGENHBG050571.
KOK07532.

Gene expression databases

ArrayExpressB4E2K6.
BgeeB4E2K6.

Family and domain databases

Gene3D1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
2.30.42.10. 1 hit.
InterProIPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001478. PDZ.
IPR011993. PH_like_dom.
IPR001849. Pleckstrin_homology.
IPR016137. Regulat_G_prot_signal_superfam.
IPR015212. RGS-like_dom.
IPR015721. RhoGEF-like.
[Graphical view]
PANTHERPTHR22825. PTHR22825. 1 hit.
PfamPF00595. PDZ. 1 hit.
PF09128. RGS-like. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTSM00228. PDZ. 1 hit.
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMSSF48065. SSF48065. 1 hit.
SSF48097. SSF48097. 1 hit.
SSF50156. SSF50156. 1 hit.
PROSITEPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50106. PDZ. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi23365.
NextBio45421.

Entry information

Entry nameB4E2K6_HUMAN
AccessionPrimary (citable) accession number: B4E2K6
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.