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B4E236

- B4E236_HUMAN

UniProt

B4E236 - B4E236_HUMAN

Protein
Submitted name:

cDNA FLJ51187, highly similar to Frizzled-6

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. Wnt-activated receptor activity Source: InterPro

    GO - Biological processi

    1. Wnt signaling pathway Source: InterPro

    Keywords - Molecular functioni

    ReceptorSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ51187, highly similar to Frizzled-6Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliB4E236.
    SMRiB4E236. Positions 2-77.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains FZ (frizzled) domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG006977.
    KOiK02376.

    Family and domain databases

    Gene3Di1.10.2000.10. 1 hit.
    InterProiIPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view]
    PANTHERiPTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    PfamiPF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view]
    PRINTSiPR00489. FRIZZLED.
    SUPFAMiSSF63501. SSF63501. 1 hit.
    PROSITEiPS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4E236-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLAQHFLPLA NLECSPNIET FLCKAFVPTC IEQIHVVPPC RKLCEKVYSD    50
    CKKLIDTFGI RWPEELECDR LQYCDETVPV TFDPHTEFLG PQKKTEQVQR 100
    DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV 150
    SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG 200
    DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI 250
    TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG 300
    VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR 350
    NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR 400
    QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG 450
    FFKRNRKRDP ISESRRVLQE SCEFFLKHNS KVKHKKKHYK PSSHKLKVIS 500
    KSMGTSTGAT ANHGTSAVAI TSHDYLGQET LTEIQTSPET SMREVKADGA 550
    STPRLREQDC GEPASPAASI SRLSGEQVDG KGQAGSVSES ARSEGRISPK 600
    SDITDTGLAQ SNNLQVPSSS EPSSLKGSTS LLVHPVSGVR KEQGGGCHSD 650
    T 651
    Length:651
    Mass (Da):72,870
    Last modified:September 23, 2008 - v1
    Checksum:i213E64F38DACAE4E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK304092 mRNA. Translation: BAG64998.1.
    RefSeqiNP_003497.2. NM_003506.3.
    UniGeneiHs.591863.
    Hs.676099.

    Genome annotation databases

    GeneIDi8323.
    KEGGihsa:8323.
    UCSCiuc011lhp.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK304092 mRNA. Translation: BAG64998.1 .
    RefSeqi NP_003497.2. NM_003506.3.
    UniGenei Hs.591863.
    Hs.676099.

    3D structure databases

    ProteinModelPortali B4E236.
    SMRi B4E236. Positions 2-77.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8323.
    KEGGi hsa:8323.
    UCSCi uc011lhp.2. human.

    Organism-specific databases

    CTDi 8323.

    Phylogenomic databases

    HOVERGENi HBG006977.
    KOi K02376.

    Miscellaneous databases

    GenomeRNAii 8323.
    NextBioi 31167.

    Family and domain databases

    Gene3Di 1.10.2000.10. 1 hit.
    InterProi IPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view ]
    PANTHERi PTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    Pfami PF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view ]
    PRINTSi PR00489. FRIZZLED.
    SUPFAMi SSF63501. SSF63501. 1 hit.
    PROSITEi PS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TracheaImported.

    Entry informationi

    Entry nameiB4E236_HUMAN
    AccessioniPrimary (citable) accession number: B4E236
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.