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Protein
Submitted name:

cDNA FLJ51187, highly similar to Frizzled-6

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51187, highly similar to Frizzled-6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevisibleiB4E236. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000351605.

Structurei

3D structure databases

ProteinModelPortaliB4E236.
SMRiB4E236. Positions 2-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG006977.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E236-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAQHFLPLA NLECSPNIET FLCKAFVPTC IEQIHVVPPC RKLCEKVYSD
60 70 80 90 100
CKKLIDTFGI RWPEELECDR LQYCDETVPV TFDPHTEFLG PQKKTEQVQR
110 120 130 140 150
DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV
160 170 180 190 200
SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG
210 220 230 240 250
DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI
260 270 280 290 300
TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG
310 320 330 340 350
VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR
360 370 380 390 400
NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR
410 420 430 440 450
QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG
460 470 480 490 500
FFKRNRKRDP ISESRRVLQE SCEFFLKHNS KVKHKKKHYK PSSHKLKVIS
510 520 530 540 550
KSMGTSTGAT ANHGTSAVAI TSHDYLGQET LTEIQTSPET SMREVKADGA
560 570 580 590 600
STPRLREQDC GEPASPAASI SRLSGEQVDG KGQAGSVSES ARSEGRISPK
610 620 630 640 650
SDITDTGLAQ SNNLQVPSSS EPSSLKGSTS LLVHPVSGVR KEQGGGCHSD

T
Length:651
Mass (Da):72,870
Last modified:September 23, 2008 - v1
Checksum:i213E64F38DACAE4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304092 mRNA. Translation: BAG64998.1.
RefSeqiNP_003497.2. NM_003506.3.
UniGeneiHs.591863.
Hs.676099.

Genome annotation databases

GeneIDi8323.
UCSCiuc011lhp.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304092 mRNA. Translation: BAG64998.1.
RefSeqiNP_003497.2. NM_003506.3.
UniGeneiHs.591863.
Hs.676099.

3D structure databases

ProteinModelPortaliB4E236.
SMRiB4E236. Positions 2-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000351605.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8323.
UCSCiuc011lhp.2. human.

Organism-specific databases

CTDi8323.

Phylogenomic databases

HOVERGENiHBG006977.

Miscellaneous databases

GenomeRNAii8323.
NextBioi31167.

Gene expression databases

GenevisibleiB4E236. HS.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TracheaImported.

Entry informationi

Entry nameiB4E236_HUMAN
AccessioniPrimary (citable) accession number: B4E236
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 22, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.