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B4E236

- B4E236_HUMAN

UniProt

B4E236 - B4E236_HUMAN

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Protein
Submitted name: cDNA FLJ51187, highly similar to Frizzled-6
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. Wnt-activated receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. Wnt signaling pathway Source: UniProtKB-KW
  2. multicellular organismal development Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

ReceptorSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51187, highly similar to Frizzled-6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Structurei

3D structure databases

ProteinModelPortaliB4E236.
SMRiB4E236. Positions 2-77.

Family & Domainsi

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG006977.
KOiK02376.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E236-1 [UniParc]FASTAAdd to Basket

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MLAQHFLPLA NLECSPNIET FLCKAFVPTC IEQIHVVPPC RKLCEKVYSD    50
CKKLIDTFGI RWPEELECDR LQYCDETVPV TFDPHTEFLG PQKKTEQVQR 100
DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV 150
SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG 200
DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI 250
TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG 300
VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR 350
NQEKLKKFMI RIGVFSGLYL VPLVTLLGCY VYEQVNRITW EITWVSDHCR 400
QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG 450
FFKRNRKRDP ISESRRVLQE SCEFFLKHNS KVKHKKKHYK PSSHKLKVIS 500
KSMGTSTGAT ANHGTSAVAI TSHDYLGQET LTEIQTSPET SMREVKADGA 550
STPRLREQDC GEPASPAASI SRLSGEQVDG KGQAGSVSES ARSEGRISPK 600
SDITDTGLAQ SNNLQVPSSS EPSSLKGSTS LLVHPVSGVR KEQGGGCHSD 650
T 651
Length:651
Mass (Da):72,870
Last modified:September 23, 2008 - v1
Checksum:i213E64F38DACAE4E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK304092 mRNA. Translation: BAG64998.1.
RefSeqiNP_003497.2. NM_003506.3.
UniGeneiHs.591863.
Hs.676099.

Genome annotation databases

GeneIDi8323.
KEGGihsa:8323.
UCSCiuc011lhp.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK304092 mRNA. Translation: BAG64998.1 .
RefSeqi NP_003497.2. NM_003506.3.
UniGenei Hs.591863.
Hs.676099.

3D structure databases

ProteinModelPortali B4E236.
SMRi B4E236. Positions 2-77.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8323.
KEGGi hsa:8323.
UCSCi uc011lhp.2. human.

Organism-specific databases

CTDi 8323.

Phylogenomic databases

HOVERGENi HBG006977.
KOi K02376.

Miscellaneous databases

GenomeRNAii 8323.
NextBioi 31167.

Family and domain databases

Gene3Di 1.10.2000.10. 1 hit.
InterProi IPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view ]
PANTHERi PTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
Pfami PF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view ]
PRINTSi PR00489. FRIZZLED.
SUPFAMi SSF63501. SSF63501. 1 hit.
PROSITEi PS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TracheaImported.

Entry informationi

Entry nameiB4E236_HUMAN
AccessioniPrimary (citable) accession number: B4E236
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 3, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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