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Protein
Submitted name:

cDNA FLJ51453, highly similar to Aquaporin-1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51453, highly similar to Aquaporin-1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei154 – 179HelicalSequence analysisAdd BLAST26
Transmembranei199 – 217HelicalSequence analysisAdd BLAST19
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Transmembranei270 – 291HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4E220
PRIDEiB4E220

Structurei

3D structure databases

ProteinModelPortaliB4E220
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 91DUF4205InterPro annotationAdd BLAST90

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0223 Eukaryota
KOG2871 Eukaryota
COG0580 LUCA
HOGENOMiHOG000288286
HOVERGENiHBG000312
PhylomeDBiB4E220

Family and domain databases

CDDicd00333 MIP, 1 hit
Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR023274 Aquaporin_1
IPR034294 Aquaporin_transptr
IPR025257 DUF4205
IPR000425 MIP
IPR022357 MIP_CS
PANTHERiPTHR19139 PTHR19139, 1 hit
PfamiView protein in Pfam
PF13898 DUF4205, 1 hit
PF00230 MIP, 1 hit
PRINTSiPR02013 AQUAPORIN1
PR00783 MINTRINSICP
SMARTiView protein in SMART
SM01174 DUF4205, 1 hit
SUPFAMiSSF81338 SSF81338, 1 hit
TIGRFAMsiTIGR00861 MIP, 1 hit
PROSITEiView protein in PROSITE
PS00221 MIP, 1 hit

Sequencei

Sequence statusi: Complete.

B4E220-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCQVGCFLKT PRFPIWVVCS ESHFSILFSL QPGLLRDWRT ERLFDLYYYD
60 70 80 90 100
GLANQQEQIR LTIDTTQTIS EDTDNDLVPP LELCIRTNIG SALGFKYPVG
110 120 130 140 150
NNQTAVQDNV KVSLAFGLSI ATLAQSVGHI SGAHLNPAVT LGLLLSCQIS
160 170 180 190 200
IFRALMYIIA QCVGAIVATA ILSGITSSLT GNSLGRNDLA DGVNSGQGLG
210 220 230 240 250
IEIIGTLQLV LCVLATTDRR RRDLGGSAPL AIGLSVALGH LLAIDYTGCG
260 270 280 290 300
INPARSFGSA VITHNFSNHW IFWVGPFIGG ALAVLIYDFI LAPRSSDLTD
310 320
RVKVWTSGQV EEYDLDADDI NSRVEMKPK
Length:329
Mass (Da):35,575
Last modified:September 23, 2008 - v1
Checksum:i1969BA704D8D2363
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK304075 mRNA Translation: BAG64982.1

Similar proteinsi

Entry informationi

Entry nameiB4E220_HUMAN
AccessioniPrimary (citable) accession number: B4E220
Secondary accession number(s): H0Y8K2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: February 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health