B4E1M2 (B4E1M2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ54951, highly similar to Epoxide hydrolase 2 (EC 3.3.2.3) EMBL BAG64834.1
Organism	Homo sapiens (Human) EMBL BAG64834.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	502 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Hydrolase EMBL BAG64834.1
Gene Ontology (GO)
Cellular_component	Golgi apparatus Inferred from direct assay. Source: HPA focal adhesion Inferred from direct assay. Source: HPA nucleolus Inferred from direct assay. Source: HPA
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4E1M2 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 562297B7EF6F5EB1	FASTA	502	56,629
	10 20 30 40 50 60 MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT TRLMKGEITL 70 80 90 100 110 120 SQWIPLMEEN CRKCSETAKV CLPKNFSIKE IFDKAISARK INRPMLQAAL MLRKKAFCSG 130 140 150 160 170 180 FTTAILTNTW LDDRAERDGL AQLMCELKMH FDFLIESCQV GMVKPEPQIY KFLLDTLKAS 190 200 210 220 230 240 PSEVVFLDDI GANLKPARDL GMVTILVQDT DTALKELEKV TGIQLLNTPA PLPTSCNPSD 250 260 270 280 290 300 MSHGYVTVKP RVRLHFVELG SGPAVCLCHG FPESWYSWRY QIPALAQAGY RVLAMDMKGY 310 320 330 340 350 360 GESSAPPEIE EYCMEVLCKE SIKANPVFDY QLYFQEPGVA EAELEQNLSR TFKSLFRASD 370 380 390 400 410 420 ESVLSMHKVC EAGGLFVNSP EEPSLSRMVT EEEIQFYVQQ FKKSGFRGPL NWYRNMERNW 430 440 450 460 470 480 KWACKSLGRK ILIPALMVTA EKDFVLVPQM SQHMEDWIPH LKRGHIEDCG HWTQMDKPTE 490 500 VNQILIKWLD SDARNPPVVS KM

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Trachea EMBL BAG64834.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK303904 mRNA. Translation: BAG64834.1.
IPI	IPI00909862.
UniGene	Hs.212088.
3D structure databases
ProteinModelPortal	B4E1M2.
SMR	B4E1M2. Positions 2-495.
ModBase	Search...
Protein-protein interaction databases
STRING	B4E1M2.
Proteomic databases
PRIDE	B4E1M2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000028073.
HOVERGEN	HBG006095.
Gene expression databases
ArrayExpress	B4E1M2.
Family and domain databases
Gene3D	1.10.150.240. 1 hit. 3.40.50.1000. 1 hit.
InterPro	IPR000073. AB_hydrolase_1. IPR023214. HAD-like_dom. IPR006402. HAD-SF_hydro_IA_v3. IPR011945. HAD-SF_ppase_IA/epoxid_hydro_N. IPR005833. Haloacid_DH/epoxide_hydro. IPR023198. PGP_dom2. [Graphical view]
Pfam	PF00561. Abhydrolase_1. 1 hit. PF13419. HAD_2. 1 hit. [Graphical view]
PRINTS	PR00413. HADHALOGNASE.
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR02247. HAD-1A3-hyp. 1 hit. TIGR01509. HAD-SF-IA-v3. 1 hit.
ProtoNet	Search...
Other
NextBio	35477068.

Entry information

Entry name

B4E1M2_HUMAN

Accession

Primary (citable) accession number: B4E1M2

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.