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Protein
Submitted name:

cDNA FLJ53952, highly similar to Fibrinogen beta chain

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53952, highly similar to Fibrinogen beta chainImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_500280403731 – 474Sequence analysisAdd BLAST444

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi224 ↔ 253PROSITE-ProRule annotation
Disulfide bondi407 ↔ 420PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQBiB4E1D3
PeptideAtlasiB4E1D3
PRIDEiB4E1D3

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4E1D3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini215 – 471Fibrinogen C-terminalInterPro annotationAdd BLAST257

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili178 – 205Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2579 Eukaryota
ENOG410ZYS4 LUCA
HOVERGENiHBG005707

Family and domain databases

CDDicd00087 FReD, 1 hit
InterProiView protein in InterPro
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR012290 Fibrinogen_a/b/g_coil_dom
IPR037580 Fibrinogen_beta
IPR020837 Fibrinogen_CS
PANTHERiPTHR19143:SF332 PTHR19143:SF332, 1 hit
PfamiView protein in Pfam
PF08702 Fib_alpha, 1 hit
PF00147 Fibrinogen_C, 1 hit
SMARTiView protein in SMART
SM00186 FBG, 1 hit
SM01212 Fib_alpha, 1 hit
SUPFAMiSSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS00514 FIBRINOGEN_C_1, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit

Sequencei

Sequence statusi: Complete.

B4E1D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRMVSWSFH KLKTMKHLLL LLLCVFLVKS QGVNDNEEGF FSARGHRPLD
60 70 80 90 100
KKREEARPAK AAATQKKVER KAPDAGGCLH ADPDLGVLCP TGCQLQEALL
110 120 130 140 150
QQERPIRNSV DELNNNVEAV SQTSSSSFQY MYLLKDLWQK RQKQVKDNEN
160 170 180 190 200
VVNEYSSELE KHQLYIDETV NSNIPTNLRV LRSILENLRS KIQKLESDVS
210 220 230 240 250
AQMEYCRTPC TVSCNIPVVS GKECEEIIRK GGETSEMYLI QPDSSVKPYR
260 270 280 290 300
VYCDMNTENG GWTVIQNRQD GSVDFGRKWD PYKQGFGNVA TNTDGKNYCG
310 320 330 340 350
LPGEYWLGND KISQLTRMGP TELLIEMEDW KGDKVKAHYG GFTVQNEANK
360 370 380 390 400
YQISVNKYRG TAGNALMDGA SQLMGENRTM TIHNGMFFST YDRDNDGWLT
410 420 430 440 450
SDPRKQCSKE DGGGWWYNRC HAANPNGRYY WGGQYTWDMA KHGTDDGVVW
460 470
MNWKGSWYSM RKMSMKIRPF FPQQ
Length:474
Mass (Da):54,253
Last modified:September 23, 2008 - v1
Checksum:i154FA4BE9CD8B475
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303788 mRNA Translation: BAG64745.1
UniGeneiHs.300774

Similar proteinsi

Entry informationi

Entry nameiB4E1D3_HUMAN
AccessioniPrimary (citable) accession number: B4E1D3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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