B4E1D3 (B4E1D3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ53952, highly similar to Fibrinogen beta chain EMBL BAG64745.1
Organism	Homo sapiens (Human) EMBL BAG64745.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	474 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 fibrinogen C-terminal domain. SAAS SAAS014715

Ontologies

Keywords
PTM	Disulfide bond SAAS SAAS014715
Gene Ontology (GO)
Biological_process	platelet activation Inferred from electronic annotation. Source: InterPro protein polymerization Inferred from electronic annotation. Source: InterPro signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	blood microparticle Inferred from electronic annotation. Source: Compara cell cortex Inferred from electronic annotation. Source: Compara fibrinogen complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4E1D3 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 154FA4BE9CD8B475	FASTA	474	54,253
	10 20 30 40 50 60 MKRMVSWSFH KLKTMKHLLL LLLCVFLVKS QGVNDNEEGF FSARGHRPLD KKREEARPAK 70 80 90 100 110 120 AAATQKKVER KAPDAGGCLH ADPDLGVLCP TGCQLQEALL QQERPIRNSV DELNNNVEAV 130 140 150 160 170 180 SQTSSSSFQY MYLLKDLWQK RQKQVKDNEN VVNEYSSELE KHQLYIDETV NSNIPTNLRV 190 200 210 220 230 240 LRSILENLRS KIQKLESDVS AQMEYCRTPC TVSCNIPVVS GKECEEIIRK GGETSEMYLI 250 260 270 280 290 300 QPDSSVKPYR VYCDMNTENG GWTVIQNRQD GSVDFGRKWD PYKQGFGNVA TNTDGKNYCG 310 320 330 340 350 360 LPGEYWLGND KISQLTRMGP TELLIEMEDW KGDKVKAHYG GFTVQNEANK YQISVNKYRG 370 380 390 400 410 420 TAGNALMDGA SQLMGENRTM TIHNGMFFST YDRDNDGWLT SDPRKQCSKE DGGGWWYNRC 430 440 450 460 470 HAANPNGRYY WGGQYTWDMA KHGTDDGVVW MNWKGSWYSM RKMSMKIRPF FPQQ

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Liver EMBL BAG64745.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK303788 mRNA. Translation: BAG64745.1.
IPI	IPI00965713.
UniGene	Hs.300774.
3D structure databases
ProteinModelPortal	B4E1D3.
SMR	B4E1D3. Positions 71-471.
ModBase	Search...
Protein-protein interaction databases
STRING	B4E1D3.
Proteomic databases
PRIDE	B4E1D3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG005707.
Gene expression databases
ArrayExpress	B4E1D3.
Bgee	B4E1D3.
Family and domain databases
Gene3D	3.90.215.10. 1 hit. 4.10.530.10. 1 hit.
InterPro	IPR014716. Fibrinogen_a/b/g_C_1. IPR014715. Fibrinogen_a/b/g_C_2. IPR002181. Fibrinogen_a/b/g_C_dom. IPR012290. Fibrinogen_a/b/g_coil_dom. IPR020837. Fibrinogen_CS. [Graphical view]
Pfam	PF08702. Fib_alpha. 1 hit. PF00147. Fibrinogen_C. 1 hit. [Graphical view]
SMART	SM00186. FBG. 1 hit. [Graphical view]
SUPFAM	SSF56496. Fibrinogen_a/b/g_C. 1 hit.
PROSITE	PS00514. FIBRINOGEN_C_1. 1 hit. PS51406. FIBRINOGEN_C_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35476999.

Entry information

Entry name

B4E1D3_HUMAN

Accession

Primary (citable) accession number: B4E1D3

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.