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Protein
Submitted name:

cDNA FLJ53952, highly similar to Fibrinogen beta chain

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular response to interleukin-1 Source: Ensembl
  2. cellular response to leptin stimulus Source: Ensembl
  3. platelet activation Source: InterPro
  4. protein polymerization Source: InterPro
  5. signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53952, highly similar to Fibrinogen beta chainImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. blood microparticle Source: Ensembl
  2. cell cortex Source: Ensembl
  3. fibrinogen complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PRIDEiB4E1D3.

Expressioni

Gene expression databases

BgeeiB4E1D3.
ExpressionAtlasiB4E1D3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB4E1D3.
SMRiB4E1D3. Positions 71-471.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fibrinogen C-terminal domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG005707.

Family and domain databases

Gene3Di3.90.215.10. 1 hit.
4.10.530.10. 1 hit.
InterProiIPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
IPR002181. Fibrinogen_a/b/g_C_dom.
IPR012290. Fibrinogen_a/b/g_coil_dom.
IPR020837. Fibrinogen_CS.
[Graphical view]
PfamiPF08702. Fib_alpha. 1 hit.
PF00147. Fibrinogen_C. 1 hit.
[Graphical view]
SMARTiSM00186. FBG. 1 hit.
[Graphical view]
SUPFAMiSSF56496. SSF56496. 1 hit.
PROSITEiPS00514. FIBRINOGEN_C_1. 1 hit.
PS51406. FIBRINOGEN_C_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E1D3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKRMVSWSFH KLKTMKHLLL LLLCVFLVKS QGVNDNEEGF FSARGHRPLD
60 70 80 90 100
KKREEARPAK AAATQKKVER KAPDAGGCLH ADPDLGVLCP TGCQLQEALL
110 120 130 140 150
QQERPIRNSV DELNNNVEAV SQTSSSSFQY MYLLKDLWQK RQKQVKDNEN
160 170 180 190 200
VVNEYSSELE KHQLYIDETV NSNIPTNLRV LRSILENLRS KIQKLESDVS
210 220 230 240 250
AQMEYCRTPC TVSCNIPVVS GKECEEIIRK GGETSEMYLI QPDSSVKPYR
260 270 280 290 300
VYCDMNTENG GWTVIQNRQD GSVDFGRKWD PYKQGFGNVA TNTDGKNYCG
310 320 330 340 350
LPGEYWLGND KISQLTRMGP TELLIEMEDW KGDKVKAHYG GFTVQNEANK
360 370 380 390 400
YQISVNKYRG TAGNALMDGA SQLMGENRTM TIHNGMFFST YDRDNDGWLT
410 420 430 440 450
SDPRKQCSKE DGGGWWYNRC HAANPNGRYY WGGQYTWDMA KHGTDDGVVW
460 470
MNWKGSWYSM RKMSMKIRPF FPQQ
Length:474
Mass (Da):54,253
Last modified:September 23, 2008 - v1
Checksum:i154FA4BE9CD8B475
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303788 mRNA. Translation: BAG64745.1.
UniGeneiHs.300774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303788 mRNA. Translation: BAG64745.1.
UniGeneiHs.300774.

3D structure databases

ProteinModelPortaliB4E1D3.
SMRiB4E1D3. Positions 71-471.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB4E1D3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG005707.

Miscellaneous databases

NextBioi35476999.

Gene expression databases

BgeeiB4E1D3.
ExpressionAtlasiB4E1D3. baseline and differential.

Family and domain databases

Gene3Di3.90.215.10. 1 hit.
4.10.530.10. 1 hit.
InterProiIPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
IPR002181. Fibrinogen_a/b/g_C_dom.
IPR012290. Fibrinogen_a/b/g_coil_dom.
IPR020837. Fibrinogen_CS.
[Graphical view]
PfamiPF08702. Fib_alpha. 1 hit.
PF00147. Fibrinogen_C. 1 hit.
[Graphical view]
SMARTiSM00186. FBG. 1 hit.
[Graphical view]
SUPFAMiSSF56496. SSF56496. 1 hit.
PROSITEiPS00514. FIBRINOGEN_C_1. 1 hit.
PS51406. FIBRINOGEN_C_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.

Entry informationi

Entry nameiB4E1D3_HUMAN
AccessioniPrimary (citable) accession number: B4E1D3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: January 7, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.