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Protein
Submitted name:

cDNA FLJ60390, highly similar to JmjC domain-containing histone demethylationprotein 3C (EC 1.14.11.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60390, highly similar to JmjC domain-containing histone demethylationprotein 3C (EC 1.14.11.-)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164721503.

PTM / Processingi

Proteomic databases

PaxDbiB4E142.
PeptideAtlasiB4E142.
PRIDEiB4E142.

Expressioni

Gene expression databases

GenevisibleiB4E142. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000370710.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 129129JmjCInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains JmjC domain.SAAS annotation

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiENOG410IT40. Eukaryota.
COG5141. LUCA.
HOVERGENiHBG080483.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR003347. JmjC_dom.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
SM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4E142-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWKTTFAWHT EDMDLYSINY LHFGEPKSWY AIPPEHGKRL ERLAQGFFPS
60 70 80 90 100
SSQGCDAFLR HKMTLISPSV LKKYGIPFDK ITQEAGEFMI TFPYGYHAGF
110 120 130 140 150
NHGFNCAEST NFATVRWIDY GKVAKLCTCR KDMVKISMDI FVRKFQPDRY
160 170 180 190 200
QLWKQGKDIY TIDHTKPTPA STPEVKAWLQ RRRKVRKASR SFQCARSTSK
210 220 230 240 250
RPKADEEEEV SDEVNGAEVP NPDSVTDDLK VSEKSEAAVK LRNTEASSEE
260 270 280 290 300
ESSASRMQVE QNLSDHIKLS GNSCLSTSVT EDIKTEDDKA YAYRSVPSIS
310 320 330 340 350
SEADDSIPLS SGYEKPEKSD PSELSWPKSP ESCSSVAESN GVLTEGEESD
360 370 380 390 400
VESHGNGLEP GEIPAVPSGE RNSFKVPSIA EGENKTSKSW RHPLSRPPAR
410 420 430 440 450
SPMTLVKQQA PSDEELPEVL SIEEEVEETE SWAKPLIHLW QTKSPNFAAE
460 470 480 490 500
QEYNATVARM KPHCAICTLL MPYHKPDSSN EENDARWETK LDEVVTSEGK
510 520 530 540 550
TKPLIPEMCF IYSEENIEYS PPNAFLEEDG TSLLISCAKC CVRVHASCYG
560 570 580 590 600
IPSHEICDGW LCARCKRNAW TAECCLCNLR GGALKETKNN KNASSADTGL
610 620
RGSLEPASSV PTVAARPPSM SLVPMLLGY
Length:629
Mass (Da):70,209
Last modified:September 23, 2008 - v1
Checksum:i3ECF5FBD3545BF68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303651 mRNA. Translation: BAG64654.1.
RefSeqiNP_055876.2. NM_015061.3.
UniGeneiHs.709425.

Genome annotation databases

GeneIDi23081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303651 mRNA. Translation: BAG64654.1.
RefSeqiNP_055876.2. NM_015061.3.
UniGeneiHs.709425.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000370710.

Proteomic databases

PaxDbiB4E142.
PeptideAtlasiB4E142.
PRIDEiB4E142.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23081.

Organism-specific databases

CTDi23081.
PharmGKBiPA164721503.

Phylogenomic databases

eggNOGiENOG410IT40. Eukaryota.
COG5141. LUCA.
HOVERGENiHBG080483.

Miscellaneous databases

GenomeRNAii23081.

Gene expression databases

GenevisibleiB4E142. HS.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR003347. JmjC_dom.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF02373. JmjC. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
SM00249. PHD. 1 hit.
[Graphical view]
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiPS51184. JMJC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ThymusImported.

Entry informationi

Entry nameiB4E142_HUMAN
AccessioniPrimary (citable) accession number: B4E142
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 6, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.