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B4E127 (B4E127_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

cDNA FLJ50939, highly similar to G/T mismatch-specific thymine DNA glycosylase (EC 3.2.2.-) EMBL BAG64639.1
Gene names
Name:TDG Ensembl ENSP00000445899
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAG64639.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Sequences

Sequence LengthMass (Da)Tools
B4E127 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: 3AABA331B277FAD8

FASTA26730,151
        10         20         30         40         50         60 
MAAYKGHHYP GPGNHFWKCL FMSGLSEVQL NHMDDHTLPG KYGIGFTNMV ERTTPGSKDL 

        70         80         90        100        110        120 
SSKEFREGGR ILVQKLQKYQ PRIAVFNGKC IYEIFSKEVF GVKVKNLEFG LQPHKIPDTE 

       130        140        150        160        170        180 
TLCYVMPSSS ARCAQFPRAQ DKVHYYIKLK DLRDQLKGIE RNMDVQEVQY TFDLQLAQED 

       190        200        210        220        230        240 
AKKMAVKEEK YDPGYEAAYG GAYGENPCSS EPCGFSSNGL IESVELRGES AFSGIPNGQW 

       250        260 
MTQSFTDQIP SFSNHCGTQE QEEESHA 

« Hide

References

« Hide 'large scale' references
[1]"The finished DNA sequence of human chromosome 12."
Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team
Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R. expand/collapse author list , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A., null.
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Thymus EMBL BAG64639.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC078819 Genomic DNA. No translation available.
AK303631 mRNA. Translation: BAG64639.1.
RefSeqNP_003202.3. NM_003211.4.
UniGeneHs.584809.

3D structure databases

ProteinModelPortalB4E127.
SMRB4E127. Positions 1-189.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000544861; ENSP00000445899; ENSG00000139372.
GeneID6996.
KEGGhsa:6996.

Organism-specific databases

CTD6996.
HGNCHGNC:11700. TDG.
PharmGKBPA36419.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG003685.
KOK03649.

Family and domain databases

Gene3D3.40.470.10. 1 hit.
InterProIPR015637. DNA_glycosylase_G/T-mismatch.
IPR003310. Thymine-DNA_glycosylase.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view]
PANTHERPTHR12159. PTHR12159. 1 hit.
PfamPF03167. UDG. 1 hit.
[Graphical view]
SUPFAMSSF52141. SSF52141. 1 hit.
TIGRFAMsTIGR00584. mug. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi6996.
NextBio27327.

Entry information

Entry nameB4E127_HUMAN
AccessionPrimary (citable) accession number: B4E127
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 9, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.