B4E0T8 (B4E0T8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ59649, highly similar to Myosin-18A EMBL BAG64550.1
Organism	Homo sapiens (Human) EMBL BAG64550.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1181 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 myosin head-like domain. SAAS SAAS001609

Ontologies

Keywords
Domain	Coiled coil SAAS SAAS001609
Ligand	ATP-binding SAAS SAAS001609 Nucleotide-binding
Molecular function	Motor protein Myosin SAAS SAAS001609
Gene Ontology (GO)
Biological_process	DNA metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	myosin complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA-dependent ATPase activity Inferred from electronic annotation. Source: InterPro motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4E0T8 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 6E94E2C214070DB6	FASTA	1,181	133,548
	10 20 30 40 50 60 MRAKTEEQIA AEEAWNETEK VWLVHRDGFS LASQLKSEEL NLPEGKVRVK LDHDGAILDV 70 80 90 100 110 120 DEDDVEKANA PSCDRLEDLA SLVYLNESSV LHTLRQRYGA SLLHTYAGPS LLVLGPRGAP 130 140 150 160 170 180 AVYSEKVMHM FKGCRREDMA PHIYAVAQTA YRAMLMSRQD QSIILLGSSG SGKTTSCQHL 190 200 210 220 230 240 VQYLATIAGI SGNKVFSVEK WQALYTLLEA FGNSPTIING NATRFSQILS LDFDQAGQVA 250 260 270 280 290 300 SASIQTMLLE KLRVARRPAS EATFNVFYYL LACGDGTLRT ELHLNHLAEN NVFGIVPLAK 310 320 330 340 350 360 PEEKQKAAQQ FSKLQAAMKV LGISPDEQKA CWFILAAIYH LGAAGATKEA AEAGRKQFAR 370 380 390 400 410 420 HEWAQKAAYL LGCSLEELSS AIFKHQHKGG TLQRSTSFRQ GPEESGLGDG TGPKLSALEC 430 440 450 460 470 480 LEGMAAGLYS ELFTLLVSLV NRALKSSQHS LCSMMIVDTP GFQNPEQGGS ARGASFEELC 490 500 510 520 530 540 HNYTQDRLQR LFHERTFVQE LERYKEENIE LAFDDLEPPT DDSVAAVDQA SHQSLVRSLA 550 560 570 580 590 600 RTDEARGLLW LLEEEALVPG ASEDTLLERL FSYYGPQEGD KKGQSPLLHS SKPHHFLLGH 610 620 630 640 650 660 SHGTNWVEYN VTGWLNYTKQ NPATQNVPRL LQDSQKKIIS NLFLGRAGSA TVLSGSIAGL 670 680 690 700 710 720 EGGSQLALRR ATSMRKTFTT GMAAVKKKSL CIQMKLQVDA LIDTIKKSKL HFVHCFLPVA 730 740 750 760 770 780 EGWAGEPRSA SSRRVNSSSE LDLPSGDHCE AGLLQLDVPL LRTQLRGSRL LDAMRMYRQG 790 800 810 820 830 840 YPDHMVFSEF RRRFDVLAPH LTKKHGRNYI VVDERRAVEE LLECLDLEKS SCCMGLSRVF 850 860 870 880 890 900 FRAGTLARLE EQRNEQTSRN LTLFQAACRG YLARQHFKKR KIQDLAIRCV QKNIKKNKGV 910 920 930 940 950 960 KDWPWWKLFT TVRPLIEVQL SEEQIRNKDE EIQQLRSKLE KAEKERNELR LNSDRLESRI 970 980 990 1000 1010 1020 SELTSELTDE RNTGESASQL LDAETAERLR AEKEMKELQT QYDALKKQME VMEMEVMEAR 1030 1040 1050 1060 1070 1080 LIRAAEINGE VDDDDAGGEW RLKYERAVRE VDFTKKRLQQ EFEDKLEVEQ QNKRQLERRL 1090 1100 1110 1120 1130 1140 GDLQADSEES QRALQQLKKK CQRLTAELQD TKLHLEGQQV RNHELEKKQR RFDSELSQAH 1150 1160 1170 1180 EEAQREKLQR EKLQREKDML LAEAFSLKHC LPPALSRWSG P

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Thymus EMBL BAG64550.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK303522 mRNA. Translation: BAG64550.1.
IPI	IPI00760925.
UniGene	Hs.462590.
3D structure databases
ProteinModelPortal	B4E0T8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000113701.
HOVERGEN	HBG103993.
Family and domain databases
Gene3D	4.10.270.10. 1 hit.
InterPro	IPR000048. IQ_motif_EF-hand-BS. IPR027401. Myosin-like_IQ_dom. IPR001609. Myosin_head_motor_dom. IPR027417. P-loop_NTPase. IPR020587. RecA_monomer-monomer_interface. [Graphical view]
Pfam	PF00063. Myosin_head. 2 hits. [Graphical view]
PRINTS	PR00193. MYOSINHEAVY.
SMART	SM00015. IQ. 1 hit. SM00242. MYSc. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
PROSITE	PS50096. IQ. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35476851.

Entry information

Entry name

B4E0T8_HUMAN

Accession

Primary (citable) accession number: B4E0T8

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	May 29, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.