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Protein
Submitted name:

Metal response element binding transcription factor 2, isoform CRA_c

Gene

MTF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Metal response element binding transcription factor 2, isoform CRA_cImported
Submitted name:
Metal-response element-binding transcription factor 2Imported
Submitted name:
cDNA FLJ50106, highly similar to Metal-response element-binding transcriptionfactor 2Imported
Gene namesi
Name:MTF2Imported
ORF Names:hCG_31944Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143033.17
HGNCiHGNC:29535 MTF2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000143033
PharmGKBiPA128394586

PTM / Processingi

Proteomic databases

PRIDEiB4DZG1

Expressioni

Gene expression databases

BgeeiENSG00000143033
ExpressionAtlasiB4DZG1 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 55PHD-typeInterPro annotationAdd BLAST55

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili429 – 449Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4323 Eukaryota
ENOG410XQ6E LUCA
HOVERGENiHBG004755

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR025894 Mtf2_C_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF14061 Mtf2_C, 1 hit
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 2 hits
SUPFAMiSSF57903 SSF57903, 2 hits
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 2 hits
PS50016 ZF_PHD_2, 1 hit

Sequencei

Sequence statusi: Complete.

B4DZG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCTICQEEY SEAPNEMVIC DKCGQGYHQL CHTPHIDSSV IDSDEKWLCR
60 70 80 90 100
QCVFATTTKR GGALKKGPNA KALQVMKQTL PYSVADLEWD AGHKTNVQQC
110 120 130 140 150
YCYCGGPGDW YLKMLQCCKC KQWFHEACVQ CLQKPMLFGD RFYTFICSVC
160 170 180 190 200
SSGPEYLKRL PLQWVDIAHL CLYNLSVIHK KKYFDSELEL MTYINENWDR
210 220 230 240 250
LHPGELADTP KSERYEHVLE ALNDYKTMFM SGKEIKKKKH LFGLRIRVPP
260 270 280 290 300
VPPNVAFKAE KEPEGTSHEF KIKGRKASKP ISDSREVSNG IEKKGKKKSV
310 320 330 340 350
GRPPGPYTRK MIQKTAEPLL DKESISENPT LDLPCSIGRT EGTAHSSNTS
360 370 380 390 400
DVDFTGASSA KETTSSSISR HYGLSDSRKR TRTGRSWPAA IPHLRRRRGR
410 420 430 440 450
LPRRALQTQN SEIVKDDEGK EDYQFDELNT EILNNLADQE LQLNHLKNSI
460 470 480 490
TSYFGAAGRI ACGEKYRVLA RRVTLDGKVQ YLVEWEGATA S
Length:491
Mass (Da):55,725
Last modified:September 23, 2008 - v1
Checksum:i662195D8854141CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093577 Genomic DNA No translation available.
AL117354 Genomic DNA No translation available.
KF459519 Genomic DNA No translation available.
AK302900 mRNA Translation: BAG64073.1
CH471097 Genomic DNA Translation: EAW73085.1
RefSeqiNP_001157863.1, NM_001164391.1
NP_001157865.1, NM_001164393.1
XP_011539318.1, XM_011541016.1
XP_016856165.1, XM_017000676.1
UniGeneiHs.31016

Genome annotation databases

EnsembliENST00000540243; ENSP00000443295; ENSG00000143033
ENST00000545708; ENSP00000444962; ENSG00000143033
GeneIDi22823
UCSCiuc010oth.3 human

Similar proteinsi

Entry informationi

Entry nameiB4DZG1_HUMAN
AccessioniPrimary (citable) accession number: B4DZG1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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