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Protein
Submitted name:

cDNA FLJ56177, highly similar to Bile salt export pump

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi589 – 596ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56177, highly similar to Bile salt export pumpImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei228 – 252HelicalSequence analysisAdd BLAST25
Transmembranei273 – 297HelicalSequence analysisAdd BLAST25
Transmembranei364 – 389HelicalSequence analysisAdd BLAST26
Transmembranei454 – 472HelicalSequence analysisAdd BLAST19
Transmembranei492 – 511HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiB4DYQ0.
PeptideAtlasiB4DYQ0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini232 – 519ABC transmembrane type-1InterPro annotationAdd BLAST288
Domaini554 – 792ABC transporterInterPro annotationAdd BLAST239

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG080809.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR030278. BSEP.
IPR027417. P-loop_NTPase.
PANTHERiPTHR24221:SF287. PTHR24221:SF287. 1 hit.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DYQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDIVQAAKE ANAYNFIMDL PQQFDTLVGE GGGQMSGGQK QRVAIARALI
60 70 80 90 100
RNPKILLLDM ATSALDNESE AMVQEVLSKI QHGHTIISVA HRLSTVRAAD
110 120 130 140 150
TIIGFEHGTA VERGTHEELL ERKGVYFTLV TLQSQGNQAL NEEDIKDATE
160 170 180 190 200
DDMLARTFSR GSYQDSLRAS IRQRSKSQLS YLVHEPPLAV VDHKSTYEED
210 220 230 240 250
RKDKDIPVQE EVEPAPVRRI LKFSAPEWPY MLVGSVGAAV NGTVTPLYAF
260 270 280 290 300
LFSQILGTFS IPDKEEQRSQ INGVCLLFVA MGCVSLFTQF LQGYAFAKSG
310 320 330 340 350
ELLTKRLRKF GFRAMLGQDI AWFDDLRNSP GALTTRLATD ASQVQGAAGS
360 370 380 390 400
QIGMIVNSFT NVTVAMIIAF SFSWKLSLVI LCFFPFLALS GATQTRMLTG
410 420 430 440 450
FASRDKQALE MVGQITNEAL SNIRTVAGIG KERRFIEALE TELEKPFKTA
460 470 480 490 500
IQKANIYGFC FAFAQCIMFI ANSASYRYGG YLISNEGLHF SYVFRVISAV
510 520 530 540 550
VLSATALGRA FSYTPSYAKA KISAARFFQL LDRQPPISVY NTAGEKWDNF
560 570 580 590 600
QGKIDFVDCK FTYPSRPDSQ VLNGLSVSIS PGQTLAFVGS SGCGKSTSIQ
610 620 630 640 650
LLERFYDPDQ GKVMIDGHDS KKVNVQFLRS NIGIVSQEPV LFACSIMDNI
660 670 680 690 700
KYGDNTKEIP MERVIAAAKQ AQLHDFVMSL PEKYETNVGS QGSQLSRGEK
710 720 730 740 750
QRIAIARAIV RDPKILLLDE ATSALDTESE KTVQVALDKA REGRTCIVIA
760 770 780 790
HRLSTIQNAD IIAVMAQGVV IEKGTHEELM AQKGAYYKLV TTGSPIS
Length:797
Mass (Da):87,776
Last modified:September 23, 2008 - v1
Checksum:i3E5B28B22F8B4375
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302540 mRNA. Translation: BAG63812.1.
UniGeneiHs.658439.

Similar proteinsi

Entry informationi

Entry nameiB4DYQ0_HUMAN
AccessioniPrimary (citable) accession number: B4DYQ0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.