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Protein
Submitted name:

cDNA FLJ56177, highly similar to Bile salt export pump

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56177, highly similar to Bile salt export pumpImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei228 – 25225HelicalSequence analysisAdd
BLAST
Transmembranei273 – 29725HelicalSequence analysisAdd
BLAST
Transmembranei364 – 38926HelicalSequence analysisAdd
BLAST
Transmembranei454 – 47219HelicalSequence analysisAdd
BLAST
Transmembranei492 – 51120HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiB4DYQ0.
PeptideAtlasiB4DYQ0.
PRIDEiB4DYQ0.

Expressioni

Gene expression databases

BgeeiB4DYQ0.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000263817.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini232 – 519288ABC transmembrane type-1InterPro annotationAdd
BLAST
Domaini554 – 792239ABC transporterInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG080809.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR030278. BSEP.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24221:SF165. PTHR24221:SF165. 1 hit.
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DYQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDIVQAAKE ANAYNFIMDL PQQFDTLVGE GGGQMSGGQK QRVAIARALI
60 70 80 90 100
RNPKILLLDM ATSALDNESE AMVQEVLSKI QHGHTIISVA HRLSTVRAAD
110 120 130 140 150
TIIGFEHGTA VERGTHEELL ERKGVYFTLV TLQSQGNQAL NEEDIKDATE
160 170 180 190 200
DDMLARTFSR GSYQDSLRAS IRQRSKSQLS YLVHEPPLAV VDHKSTYEED
210 220 230 240 250
RKDKDIPVQE EVEPAPVRRI LKFSAPEWPY MLVGSVGAAV NGTVTPLYAF
260 270 280 290 300
LFSQILGTFS IPDKEEQRSQ INGVCLLFVA MGCVSLFTQF LQGYAFAKSG
310 320 330 340 350
ELLTKRLRKF GFRAMLGQDI AWFDDLRNSP GALTTRLATD ASQVQGAAGS
360 370 380 390 400
QIGMIVNSFT NVTVAMIIAF SFSWKLSLVI LCFFPFLALS GATQTRMLTG
410 420 430 440 450
FASRDKQALE MVGQITNEAL SNIRTVAGIG KERRFIEALE TELEKPFKTA
460 470 480 490 500
IQKANIYGFC FAFAQCIMFI ANSASYRYGG YLISNEGLHF SYVFRVISAV
510 520 530 540 550
VLSATALGRA FSYTPSYAKA KISAARFFQL LDRQPPISVY NTAGEKWDNF
560 570 580 590 600
QGKIDFVDCK FTYPSRPDSQ VLNGLSVSIS PGQTLAFVGS SGCGKSTSIQ
610 620 630 640 650
LLERFYDPDQ GKVMIDGHDS KKVNVQFLRS NIGIVSQEPV LFACSIMDNI
660 670 680 690 700
KYGDNTKEIP MERVIAAAKQ AQLHDFVMSL PEKYETNVGS QGSQLSRGEK
710 720 730 740 750
QRIAIARAIV RDPKILLLDE ATSALDTESE KTVQVALDKA REGRTCIVIA
760 770 780 790
HRLSTIQNAD IIAVMAQGVV IEKGTHEELM AQKGAYYKLV TTGSPIS
Length:797
Mass (Da):87,776
Last modified:September 23, 2008 - v1
Checksum:i3E5B28B22F8B4375
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302540 mRNA. Translation: BAG63812.1.
UniGeneiHs.658439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302540 mRNA. Translation: BAG63812.1.
UniGeneiHs.658439.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000263817.

Proteomic databases

PaxDbiB4DYQ0.
PeptideAtlasiB4DYQ0.
PRIDEiB4DYQ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
HOVERGENiHBG080809.

Gene expression databases

BgeeiB4DYQ0.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR030278. BSEP.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24221:SF165. PTHR24221:SF165. 1 hit.
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiB4DYQ0_HUMAN
AccessioniPrimary (citable) accession number: B4DYQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 6, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.