ID   B4DYI6_HUMAN            Unreviewed;       255 AA.
AC   B4DYI6;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   24-JAN-2024, entry version 82.
DE   SubName: Full=cDNA FLJ60196, highly similar to Methylglutaconyl-CoA hydratase, mitochondrial {ECO:0000313|EMBL:BAG63748.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG63748.1};
RN   [1] {ECO:0000313|EMBL:BAG63748.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis {ECO:0000313|EMBL:BAG63748.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
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DR   EMBL; AK302453; BAG63748.1; -; mRNA.
DR   RefSeq; XP_005252129.1; XM_005252072.2.
DR   AlphaFoldDB; B4DYI6; -.
DR   SMR; B4DYI6; -.
DR   IntAct; B4DYI6; 5.
DR   MaxQB; B4DYI6; -.
DR   PeptideAtlas; B4DYI6; -.
DR   ProteomicsDB; 5528; -.
DR   DNASU; 549; -.
DR   GeneID; 549; -.
DR   CTD; 549; -.
DR   OrthoDB; 177540at2759; -.
DR   BioGRID-ORCS; 549; 8 hits in 1159 CRISPR screens.
DR   GenomeRNAi; 549; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   PANTHER; PTHR11941; ENOYL-COA HYDRATASE-RELATED; 1.
DR   PANTHER; PTHR11941:SF12; METHYLGLUTACONYL-COA HYDRATASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990}.
SQ   SEQUENCE   255 AA;  26335 MW;  07D5F5EDE1273C7A CRC64;
     MAAAVAAAPG ALGSLHAGGA RLVAACSAWL CPGLRLPGSL AGRRAGPAIW AQGWVPAAGG
     PAPKRGYSSE MKTEDELRVR HLEEENRGIV VLGINRAYGK NSLSKNLIKM LSKAVDALKS
     DKKVRTIIIR SEVPGIFCAG ADLKERAKMS SSEVGPFVSK IRAVINDIAN LPVPTIAAID
     GLALGGGLEL ALACDIRVAA SSAKMGLVET KLAIIPGGVT SSTEVLNPSK SSMKIGIIIF
     QTPVNIDILA SSHES
//