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Protein
Submitted name:

Heterogeneous nuclear ribonucleoproteins C1/C2

Gene

HNRNPC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRibonucleoproteinImported, Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoproteins C1/C2Imported
Submitted name:
cDNA FLJ53542, highly similar to Heterogeneous nuclear ribonucleoproteins CImported
Gene namesi
Name:HNRNPCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:5035. HNRNPC.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Virion

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000092199.

Expressioni

Gene expression databases

BgeeiENSG00000092199.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000319690.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 87RRM (RNA recognition motif)InterPro annotationAdd BLAST72

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili180 – 223Sequence analysisAdd BLAST44

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0118. Eukaryota.
COG0724. LUCA.
GeneTreeiENSGT00390000006718.
HOVERGENiHBG002302.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiView protein in InterPro
IPR017347. hnRNP_C.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
PIRSFiPIRSF037992. hnRNP-C_Raly. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DY08-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASNVTNKTD PRSMNSRVFI GNLNTLVVKK SDVEAIFSKY GKIVGCSVHK
60 70 80 90 100
GFAFVQYVNE RNARAAVAGE DGRMIAGQVL DINLAAEPKV NRGKAGVKRS
110 120 130 140 150
AAEMYGSSFD LDYDFQRDYY DRMYSYPARV PPPPPIARAV VPSKRQRVSG
160 170 180 190 200
NTSRRGKSGF NSKSGQRGSS KSGKLKGDDL QAIKKELTQI KQKVDSLLEN
210 220 230 240 250
LEKIEKEQSK QAVEMKNDKS EEEQSSSSVK KDETNVKMES EGGADDSAEE
260 270 280
GDLLDDDDNE DRGDDQVKTT GKERKRWWRG AQGHMECL
Length:288
Mass (Da):31,972
Last modified:September 23, 2008 - v1
Checksum:iC02D787700558C29
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135744 Genomic DNA. No translation available.
AK302213 mRNA. Translation: BAG63570.1.
UniGeneiHs.508848.
Hs.675546.

Genome annotation databases

EnsembliENST00000336053; ENSP00000338095; ENSG00000092199.
ENST00000553753; ENSP00000450548; ENSG00000092199.
UCSCiuc001wae.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL135744 Genomic DNA. No translation available.
AK302213 mRNA. Translation: BAG63570.1.
UniGeneiHs.508848.
Hs.675546.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000319690.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000336053; ENSP00000338095; ENSG00000092199.
ENST00000553753; ENSP00000450548; ENSG00000092199.
UCSCiuc001wae.4. human.

Organism-specific databases

HGNCiHGNC:5035. HNRNPC.
OpenTargetsiENSG00000092199.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0118. Eukaryota.
COG0724. LUCA.
GeneTreeiENSGT00390000006718.
HOVERGENiHBG002302.

Miscellaneous databases

ChiTaRSiHNRNPC. human.

Gene expression databases

BgeeiENSG00000092199.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiView protein in InterPro
IPR017347. hnRNP_C.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
PIRSFiPIRSF037992. hnRNP-C_Raly. 1 hit.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB4DY08_HUMAN
AccessioniPrimary (citable) accession number: B4DY08
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 15, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.