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B4DXS1

- B4DXS1_HUMAN

UniProt

B4DXS1 - B4DXS1_HUMAN

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Protein

Glycylpeptide N-tetradecanoyltransferase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.UniRule annotation

Catalytic activityi

Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.UniRule annotation

GO - Molecular functioni

  1. glycylpeptide N-tetradecanoyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. N-terminal protein myristoylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glycylpeptide N-tetradecanoyltransferaseUniRule annotation (EC:2.3.1.97UniRule annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

ExpressionAtlasiB4DXS1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB4DXS1.
SMRiB4DXS1. Positions 1-310.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NMT family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG003404.

Family and domain databases

Gene3Di3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000903. MyristoylCoA_TrFase.
IPR022677. MyristoylCoA_TrFase_C.
IPR022678. MyristoylCoA_TrFase_CS.
IPR022676. MyristoylCoA_TrFase_N.
[Graphical view]
PANTHERiPTHR11377. PTHR11377. 1 hit.
PfamiPF01233. NMT. 1 hit.
PF02799. NMT_C. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 2 hits.
PROSITEiPS00975. NMT_1. 1 hit.
PS00976. NMT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DXS1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFRFDYSPEF LLWALRPPGW LLQWHCGVRV SSNKKLVGFI SAIPANIRIY
60 70 80 90 100
DSVKKMVEIN FLCVHKKLRS KRVAPVLIRE ITRRVNLEGI FQAVYTAGVV
110 120 130 140 150
LPKPIATCRY WHRSLNPRKL VEVKFSHLSR NMTLQRTMKL YRLPDVTKTS
160 170 180 190 200
GLRPMEPKDI KSVRELINTY LKQFHLAPVM DEEEVAHWFL PREHIIDTFV
210 220 230 240 250
VESPNGKLTD FLSFYTLPST VMHHPAHKSL KAAYSFYNIH TETPLLDLMS
260 270 280 290 300
DALILAKSKG FDVFNALDLM ENKTFLEKLK FGIGDGNLQY YLYNWRCPGT
310
DSEKVGLVLQ
Length:310
Mass (Da):35,986
Last modified:September 23, 2008 - v1
Checksum:iCAC25DFE8B10346C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK302101 mRNA. Translation: BAG63483.1.
UniGeneiHs.60339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK302101 mRNA. Translation: BAG63483.1 .
UniGenei Hs.60339.

3D structure databases

ProteinModelPortali B4DXS1.
SMRi B4DXS1. Positions 1-310.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG003404.

Miscellaneous databases

ChiTaRSi NMT2. human.
NextBioi 35476048.

Gene expression databases

ExpressionAtlasi B4DXS1. baseline and differential.

Family and domain databases

Gene3Di 3.40.630.30. 2 hits.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000903. MyristoylCoA_TrFase.
IPR022677. MyristoylCoA_TrFase_C.
IPR022678. MyristoylCoA_TrFase_CS.
IPR022676. MyristoylCoA_TrFase_N.
[Graphical view ]
PANTHERi PTHR11377. PTHR11377. 1 hit.
Pfami PF01233. NMT. 1 hit.
PF02799. NMT_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 2 hits.
PROSITEi PS00975. NMT_1. 1 hit.
PS00976. NMT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiB4DXS1_HUMAN
AccessioniPrimary (citable) accession number: B4DXS1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.