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B4DXS1

- B4DXS1_HUMAN

UniProt

B4DXS1 - B4DXS1_HUMAN

Protein

Glycylpeptide N-tetradecanoyltransferase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.UniRule annotation

    Catalytic activityi

    Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.UniRule annotation

    GO - Molecular functioni

    1. glycylpeptide N-tetradecanoyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. N-terminal protein myristoylation Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotation, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycylpeptide N-tetradecanoyltransferaseUniRule annotation (EC:2.3.1.97UniRule annotation)
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NMT family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG003404.

    Family and domain databases

    Gene3Di3.40.630.30. 2 hits.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR000903. MyristoylCoA_TrFase.
    IPR022677. MyristoylCoA_TrFase_C.
    IPR022678. MyristoylCoA_TrFase_CS.
    IPR022676. MyristoylCoA_TrFase_N.
    [Graphical view]
    PANTHERiPTHR11377. PTHR11377. 1 hit.
    PfamiPF01233. NMT. 1 hit.
    PF02799. NMT_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 2 hits.
    PROSITEiPS00975. NMT_1. 1 hit.
    PS00976. NMT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4DXS1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFRFDYSPEF LLWALRPPGW LLQWHCGVRV SSNKKLVGFI SAIPANIRIY    50
    DSVKKMVEIN FLCVHKKLRS KRVAPVLIRE ITRRVNLEGI FQAVYTAGVV 100
    LPKPIATCRY WHRSLNPRKL VEVKFSHLSR NMTLQRTMKL YRLPDVTKTS 150
    GLRPMEPKDI KSVRELINTY LKQFHLAPVM DEEEVAHWFL PREHIIDTFV 200
    VESPNGKLTD FLSFYTLPST VMHHPAHKSL KAAYSFYNIH TETPLLDLMS 250
    DALILAKSKG FDVFNALDLM ENKTFLEKLK FGIGDGNLQY YLYNWRCPGT 300
    DSEKVGLVLQ 310
    Length:310
    Mass (Da):35,986
    Last modified:September 23, 2008 - v1
    Checksum:iCAC25DFE8B10346C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK302101 mRNA. Translation: BAG63483.1.
    UniGeneiHs.60339.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK302101 mRNA. Translation: BAG63483.1 .
    UniGenei Hs.60339.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG003404.

    Miscellaneous databases

    ChiTaRSi NMT2. human.
    NextBioi 35476048.

    Family and domain databases

    Gene3Di 3.40.630.30. 2 hits.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR000903. MyristoylCoA_TrFase.
    IPR022677. MyristoylCoA_TrFase_C.
    IPR022678. MyristoylCoA_TrFase_CS.
    IPR022676. MyristoylCoA_TrFase_N.
    [Graphical view ]
    PANTHERi PTHR11377. PTHR11377. 1 hit.
    Pfami PF01233. NMT. 1 hit.
    PF02799. NMT_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 2 hits.
    PROSITEi PS00975. NMT_1. 1 hit.
    PS00976. NMT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiB4DXS1_HUMAN
    AccessioniPrimary (citable) accession number: B4DXS1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.