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Protein
Submitted name:

cDNA FLJ60942, highly similar to Phosphatidylinositol 3-kinase regulatory subunit gamma

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

SignaLinkiB4DXM8.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60942, highly similar to Phosphatidylinositol 3-kinase regulatory subunit gammaImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

MaxQBiB4DXM8.
PaxDbiB4DXM8.
PeptideAtlasiB4DXM8.
PRIDEiB4DXM8.

PTM databases

iPTMnetiB4DXM8.

Structurei

3D structure databases

ProteinModelPortaliB4DXM8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 206SH2InterPro annotationAdd BLAST96
Domaini404 – 498SH2InterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili227 – 254Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SH2 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4637. Eukaryota.
ENOG410XP6R. LUCA.
HOGENOMiHOG000008438.
HOVERGENiHBG082100.

Family and domain databases

CDDicd09930. SH2_cSH2_p85_like. 1 hit.
cd09942. SH2_nSH2_p85_like. 1 hit.
Gene3Di3.30.505.10. 2 hits.
InterProiView protein in InterPro
IPR032498. PI3K_P85_iSH2.
IPR001720. PI3kinase_P85.
IPR035020. PI3kinase_P85_cSH2.
IPR035022. PI3kinase_P85_nSH2.
IPR000980. SH2.
PANTHERiPTHR10155. PTHR10155. 1 hit.
PfamiView protein in Pfam
PF16454. PI3K_P85_iSH2. 1 hit.
PF00017. SH2. 2 hits.
PRINTSiPR00401. SH2DOMAIN.
SMARTiView protein in SMART
SM00252. SH2. 2 hits.
SUPFAMiSSF55550. SSF55550. 2 hits.
PROSITEiView protein in PROSITE
PS50001. SH2. 2 hits.

Sequencei

Sequence statusi: Complete.

B4DXM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPSRLVRGP RPQGMRSPYR RPGMGWPRPR FPRMFKCSRR RYQQGLRGRT
60 70 80 90 100
ASSAAINPAT RAMGINNTHT DTTIVWIFPP QALPPKPPKP MTSAVPNGMK
110 120 130 140 150
DSSVSLQDAE WYWGDISREE VNDKLRDMPD GTFLVRDAST KMQGDYTLTL
160 170 180 190 200
RKGGNNKLIK IYHRDGKYGF SDPLTFNSVV ELINHYHHES LAQYNPKLDV
210 220 230 240 250
KLMYPVSRYQ QDQLVKEDNI DAVGKKLQEY HSQYQEKSKE YDRLYEEYTR
260 270 280 290 300
TSQEIQMKRT AIEAFNETIK IFEEQCHTQE QHSKEYIERF RREGNEKEIE
310 320 330 340 350
RIMMNYDKLK SRLGEIHDSK MRLEQDLKKQ ALDNREIDKK MNSIKPDLIQ
360 370 380 390 400
LRKIRDQHLV WLNHKGVRQK RLNVWLGIKN EDADENYFIN EEDENLPHYD
410 420 430 440 450
EKTWFVEDIN RVQAEDLLYG KPDGAFLIRE SSKKGCYACS VVADGEVKHC
460 470 480 490 500
VIYSTARGYG FAEPYNLYSS LKELVLHYQQ TSLVQHNDSL NVRLAYPVHA

QMPSLCR
Length:507
Mass (Da):59,408
Last modified:September 23, 2008 - v1
Checksum:iD5ED1AA984465CC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302049 mRNA. Translation: BAG63440.1.
RefSeqiNP_001290356.1. NM_001303427.1.
NP_001290357.1. NM_001303428.1.
UniGeneiHs.655387.

Genome annotation databases

GeneIDi110117499.
8503.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB4DXM8_HUMAN
AccessioniPrimary (citable) accession number: B4DXM8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 5, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.