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Protein

GrpE protein homolog

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
GrpE protein homologUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Mitochondrion matrix UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

MitochondrionUniRule annotation

PTM / Processingi

Proteomic databases

MaxQBiB4DWV5.
PeptideAtlasiB4DWV5.
PRIDEiB4DWV5.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4DWV5.
SMRiB4DWV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili40 – 77Sequence analysisAdd BLAST38

Sequence similaritiesi

Belongs to the GrpE family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000252083.
HOVERGENiHBG051846.

Family and domain databases

CDDicd00446. GrpE. 1 hit.
Gene3Di2.30.22.10. 1 hit.
3.90.20.20. 1 hit.
HAMAPiMF_01151. GrpE. 1 hit.
InterProiView protein in InterPro
IPR000740. GrpE.
IPR013805. GrpE_coiled_coil.
IPR009012. GrpE_head.
PANTHERiPTHR21237. PTHR21237. 1 hit.
PfamiView protein in Pfam
PF01025. GrpE. 1 hit.
PRINTSiPR00773. GRPEPROTEIN.
SUPFAMiSSF51064. SSF51064. 1 hit.
PROSITEiView protein in PROSITE
PS01071. GRPE. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DWV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQCVRLAR RSLPALALSL RPSPRLLCTA TKQKNSGQNL EEDMGQSEQL
60 70 80 90 100
KETVEKYKRA LADTENLRQR SQKLVEEAKL YGIQAFCKDL LEVADVLEKA
110 120 130 140 150
TQCVPKEEIK DDNPHLKNLY EGLVMTEVQI QKVFTKHGLL KLNPVGAKFD
160 170 180 190
PYEHEALFHT PVEGKEPGTV ALVSKVGYKL HGRTLRPALV GVVKEA
Length:196
Mass (Da):21,900
Last modified:September 23, 2008 - v1
Checksum:i22A6D384C652AC17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301695 mRNA. Translation: BAG63167.1.
UniGeneiHs.443723.

Similar proteinsi

Entry informationi

Entry nameiB4DWV5_HUMAN
AccessioniPrimary (citable) accession number: B4DWV5
Secondary accession number(s): E7EWH0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: August 30, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.