Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B4DWQ2 (B4DWQ2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

cDNA FLJ51356, highly similar to Activin receptor type 2A (EC 2.7.11.30) EMBL BAG63114.1
Gene names
Name:ACVR2A Ensembl ENSP00000439988
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAG63114.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Sequences

Sequence LengthMass (Da)Tools
B4DWQ2 [UniParc].

Last modified September 23, 2008. Version 1.
Checksum: F0D4F7B18BD200AB

FASTA40545,713
        10         20         30         40         50         60 
MCNEKFSYFP EMEVTQPTSN PVTPKPPYYN ILLYSLVPLM LIAGIVICAF WVYRHHKMAY 

        70         80         90        100        110        120 
PPVLVPTQDP GPPPPSPLLG LKPLQLLEVK ARGRFGCVWK AQLLNEYVAV KIFPIQDKQS 

       130        140        150        160        170        180 
WQNEYEVYSL PGMKHENILQ FIGAEKRGTS VDVDLWLITA FHEKGSLSDF LKANVVSWNE 

       190        200        210        220        230        240 
LCHIAETMAR GLAYLHEDIP GLKDGHKPAI SHRDIKSKNV LLKNNLTACI ADFGLALKFE 

       250        260        270        280        290        300 
AGKSAGDTHG QVGTRRYMAP EVLEGAINFQ RDAFLRIDMY AMGLVLWELA SRCTAADGPV 

       310        320        330        340        350        360 
DEYMLPFEEE IGQHPSLEDM QEVVVHKKKR PVLRDYWQKH AGMAMLCETI EECWDHDAEA 

       370        380        390        400 
RLSAGCVGER ITQMQRLTNI ITTEDIVTVV TMVTNVDFPP KESSL 

« Hide

References

« Hide 'large scale' references
[1]"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. expand/collapse author list , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Colon EMBL BAG63114.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC009480 Genomic DNA. No translation available.
AK301629 mRNA. Translation: BAG63114.1.
RefSeqNP_001265508.1. NM_001278579.1.
NP_001265509.1. NM_001278580.1.
UniGeneHs.470174.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000535787; ENSP00000439988; ENSG00000121989.
GeneID92.
KEGGhsa:92.

Organism-specific databases

CTD92.
HGNCHGNC:173. ACVR2A.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG054502.
KOK04670.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR000333. TGFB_receptor.
[Graphical view]
PANTHERPTHR23255:SF10. PTHR23255:SF10. 1 hit.
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSPR00653. ACTIVIN2R.
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi92.
NextBio35475783.

Entry information

Entry nameB4DWQ2_HUMAN
AccessionPrimary (citable) accession number: B4DWQ2
Entry history
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.