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B4DWG8

- B4DWG8_HUMAN

UniProt

B4DWG8 - B4DWG8_HUMAN

Protein
Submitted name:

cDNA FLJ60923, highly similar to Phosphate-regulating neutral endopeptidase (EC3.4.24.-)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (23 Sep 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro

    GO - Biological processi

    1. bone mineralization Source: Ensembl
    2. organophosphate metabolic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ60923, highly similar to Phosphate-regulating neutral endopeptidase (EC3.4.24.-)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: Ensembl
    2. Golgi apparatus Source: Ensembl
    3. perinuclear region of cytoplasm Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG005554.
    KOiK08636.

    Family and domain databases

    Gene3Di3.40.390.10. 2 hits.
    InterProiIPR024079. MetalloPept_cat_dom.
    IPR000718. Peptidase_M13.
    IPR018497. Peptidase_M13_C.
    IPR008753. Peptidase_M13_N.
    [Graphical view]
    PANTHERiPTHR11733. PTHR11733. 1 hit.
    PfamiPF01431. Peptidase_M13. 1 hit.
    PF05649. Peptidase_M13_N. 1 hit.
    [Graphical view]
    PRINTSiPR00786. NEPRILYSIN.

    Sequencei

    Sequence statusi: Complete.

    B4DWG8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPSYGVYPWL RHNVDLKLKE LLEKSISRRR DTEAIQKAKI LYSSCMNEKA    50
    IEKADAKPLL HILRHSPFRW PVLESNIGPE GVWSERKFSL LQTLATFRGQ 100
    YSNSVFIRLY VSPDDKASNE HILKLDQATL SLAVREDYLD NSTEAKSYRD 150
    ALYKFMVDTA VLLGANSSRA EHDMKSVLRL EIKIAEIMIP HENRTSEAMY 200
    NKMNISELSA MIPQFDWLGY IKKVIDTRLY PHLKDISPSE NVVVRVPQYF 250
    KDLFRILGSE RKKTIANYLV WRMVYSRIPN LSRRFQYRWL EFSRVIQGTT 300
    TLLPQWDKCV NFIESALPYV VGKMFVDVYF QEDKKEMMEE LVEGVRWAFI 350
    DMLEKENEWM DAGTKRKAKE KARAVLAKVG YPEFIMNDTH VNEDLKAIKF 400
    SEADYFGNVL QTRKYLAQSD FFWLRKAVPK TEWFTNPTTV NAFYSASTNQ 450
    IRFPAGELQK PFFWGTEYPR SLSYGAIGVI VGHEFTHGFD NNGRKYDKNG 500
    NLDPWWSTES EEKFKEKTKC MINQYSNYYW KKAGLNVKGK RTLGENIADN 550
    GGLREAFRAY RKWINDRRQG LEEPLLPGIT FTNNQLFFLS YAHVRCNSYR 600
    PEAAREQVQI GAHSPPQFRV NGAISNFEEF QKAFNCPPNS TMNRGMDSCR 650
    LW 652
    Length:652
    Mass (Da):76,100
    Last modified:September 23, 2008 - v1
    Checksum:i7369FB60ED0365AF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK301528 mRNA. Translation: BAG63030.1.
    RefSeqiNP_000435.3. NM_000444.5.
    NP_001269683.1. NM_001282754.1.
    UniGeneiHs.495834.

    Genome annotation databases

    GeneIDi5251.
    KEGGihsa:5251.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK301528 mRNA. Translation: BAG63030.1 .
    RefSeqi NP_000435.3. NM_000444.5.
    NP_001269683.1. NM_001282754.1.
    UniGenei Hs.495834.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5251.
    KEGGi hsa:5251.

    Organism-specific databases

    CTDi 5251.

    Phylogenomic databases

    HOVERGENi HBG005554.
    KOi K08636.

    Miscellaneous databases

    ChiTaRSi PHEX. human.
    GenomeRNAii 5251.
    NextBioi 35475716.

    Family and domain databases

    Gene3Di 3.40.390.10. 2 hits.
    InterProi IPR024079. MetalloPept_cat_dom.
    IPR000718. Peptidase_M13.
    IPR018497. Peptidase_M13_C.
    IPR008753. Peptidase_M13_N.
    [Graphical view ]
    PANTHERi PTHR11733. PTHR11733. 1 hit.
    Pfami PF01431. Peptidase_M13. 1 hit.
    PF05649. Peptidase_M13_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00786. NEPRILYSIN.
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Synovial membrane tissueImported.

    Entry informationi

    Entry nameiB4DWG8_HUMAN
    AccessioniPrimary (citable) accession number: B4DWG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.