ID   B4DW96_HUMAN            Unreviewed;       414 AA.
AC   B4DW96;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   22-FEB-2023, entry version 37.
DE   SubName: Full=cDNA FLJ51119, highly similar to Ras and Rab interactor 1 {ECO:0000313|EMBL:BAG62958.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG62958.1};
RN   [1] {ECO:0000313|EMBL:BAG62958.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Synovial membrane tissue {ECO:0000313|EMBL:BAG62958.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK301430; BAG62958.1; -; mRNA.
DR   AlphaFoldDB; B4DW96; -.
DR   PeptideAtlas; B4DW96; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR003123; VPS9.
DR   InterPro; IPR045046; Vps9-like.
DR   InterPro; IPR037191; VPS9_dom_sf.
DR   PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR23101:SF62; RAS AND RAB INTERACTOR 1; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF02204; VPS9; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00167; VPS9; 1.
DR   SUPFAM; SSF109993; VPS9 domain; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS51205; VPS9; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          93..229
FT                   /note="VPS9"
FT                   /evidence="ECO:0000259|PROSITE:PS51205"
FT   DOMAIN          255..337
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   414 AA;  44790 MW;  A21EBD2E426069A9 CRC64;
     MPSLQEVDCG SPSSSEEEGV PGSRGSPATS PHLGRRRPLL RSMSAAFCSL LAPERQVGRA
     AAALMQDRHT AAGQLVQDLL TQVRAGPEPQ ELQGIRQALS RARAMLSAEL GPEKLLSPKR
     LELEQVRQKL LQLLRTYSPS AQVKRLLQAC KLLYMALRTQ EGEGAGADEF LPLLSLVLAH
     CDLPELLLEA EYMSELLEPS LLTGEGGYYL TSLSASLALL SGLGQAHTLP LSPVQELRRS
     LSLWEQRRLP ATHCFQHLLR VAYQDPSSGC TSKTLAVPPE ASIATLNQLC ATKFRVTQPN
     TFGLFLYKEQ GYHRLPPGAL AHRLPTTGYL VYRRAEWPET QGAVTEEEGS GQSEARSRGE
     EQGCQGDGDA GVKASPRDIR EQSETTAEGG QGQAQEGPAQ PGEPEAEGSR AAEE
//