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Protein
Submitted name:

cDNA FLJ50887, highly similar to PR domain zinc finger protein 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: InterPro
  2. nucleic acid binding Source: InterPro
  3. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. cellular developmental process Source: InterPro
  2. negative regulation of transcription from RNA polymerase II promoter Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50887, highly similar to PR domain zinc finger protein 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
  2. nucleus Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB4DW27.
ExpressionAtlasiB4DW27. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation

Phylogenomic databases

HOVERGENiHBG053670.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR016608. PRDM1.
IPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR11389:SF339. PTHR11389:SF339. 1 hit.
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B4DW27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKIYSRGEL HHFIDGFNEE KSNWMRYVNP AHSPREQNLA ACQNGMNIYF
60 70 80 90 100
YTIKPIPANQ ELLVWYCRDF AERLHYPYPG ELTMMNLTQT QSSLKQPSTE
110 120 130 140 150
KNELCPKNVP KREYSVKEIL KLDSNPSKGK DLYRSNISPL TSEKDLDDFR
160 170 180 190 200
RRGSPEMPFY PRVVYPIRAP LPEDFLKASL AYGIERPTYI TRSPIPSSTT
210 220 230 240 250
PSPSARSSPD QSLKSSSPHS SPGNTVSPVG PGSQEHRDSY AYLNASYGTE
260 270 280 290 300
GLGSYPGYAP LPHLPPAFIP SYNAHYPKFL LPPYGMNCNG LSAVSSMNGI
310 320 330 340 350
NNFGLFPRLC PVYSNLLGGG SLPHPMLNPT SLPSSLPSDG ARRLLQPEHP
360 370 380 390 400
REVLVPAPHS AFSFTGAAAS MKDKACSPTS GSPTAGTAAT AEHVVQPKAT
410 420 430 440 450
SAAMAAPSSD EAMNLIKNKR NMTGYKTLPY PLKKQNGKIK YECNVCAKTF
460 470 480 490 500
GQLSNLKVHL RVHSGERPFK CQTCNKGFTQ LAHLQKHYLV HTGEKPHECQ
510 520 530 540 550
VCHKRFSSTS NLKTHLRLHS GEKPYQCKVC PAKFTQFVHL KLHKRLHTRE
560 570 580 590 600
RPHKCSQCHK NYIHLCSLKV HLKGNCAAAP APGLPLEDLT RINEEIEKFD
610 620
ISDNADRLED VEDDISVISV VEKEILAVV
Length:629
Mass (Da):70,046
Last modified:September 22, 2008 - v1
Checksum:i17E63BE19CC57AE7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei629 – 6291Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301341 mRNA. Translation: BAG62889.1.
RefSeqiNP_878911.1. NM_182907.2.
UniGeneiHs.436023.

Genome annotation databases

GeneIDi639.
KEGGihsa:639.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301341 mRNA. Translation: BAG62889.1.
RefSeqiNP_878911.1. NM_182907.2.
UniGeneiHs.436023.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi639.
KEGGihsa:639.

Organism-specific databases

CTDi639.

Phylogenomic databases

HOVERGENiHBG053670.

Miscellaneous databases

GenomeRNAii639.
NextBioi2590.

Gene expression databases

BgeeiB4DW27.
ExpressionAtlasiB4DW27. baseline and differential.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR016608. PRDM1.
IPR001214. SET_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR11389:SF339. PTHR11389:SF339. 1 hit.
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS50280. SET. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Synovial membrane tissueImported.

Entry informationi

Entry nameiB4DW27_HUMAN
AccessioniPrimary (citable) accession number: B4DW27
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2008
Last sequence update: September 22, 2008
Last modified: March 31, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.