Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Hydroxyacid-oxoacid transhydrogenase, mitochondrial

Gene

ADHFE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxyacid-oxoacid transhydrogenase, mitochondrialImported
Submitted name:
cDNA FLJ53664, highly similar to Rattus norvegicus alcohol dehydrogenase, iron containing, 1 (Adhfe1), mRNAImported
Gene namesi
Name:ADHFE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:16354. ADHFE1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000147576.

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DV11.

Expressioni

Gene expression databases

BgeeiENSG00000147576.
ExpressionAtlasiB4DV11. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000379865.

Structurei

3D structure databases

ProteinModelPortaliB4DV11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 120Fe-ADHInterPro annotationAdd BLAST68

Phylogenomic databases

eggNOGiKOG3857. Eukaryota.
COG1454. LUCA.
GeneTreeiENSGT00390000003849.
HOGENOMiHOG000069907.
HOVERGENiHBG103454.

Family and domain databases

InterProiIPR001670. ADH_Fe.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DV11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAARARVA YLLRQLQRAA CQCPTHSHTY SQAPGLSPSG KTTDYAFEMA
60 70 80 90 100
VSNIRYGAAV TKEVGMDLKN MGAKNVCLMT DKNLSKLPPV QVAMDSLVKN
110 120
GIPFTVYDNV RVEPTDSSAN YLRNRE
Length:126
Mass (Da):13,770
Last modified:September 23, 2008 - v1
Checksum:i9AAC8D7F89449762
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009879 Genomic DNA. No translation available.
KF458771 Genomic DNA. No translation available.
AK300881 mRNA. Translation: BAG62523.1.
UniGeneiHs.720023.

Genome annotation databases

EnsembliENST00000396621; ENSP00000379864; ENSG00000147576.
UCSCiuc064niv.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009879 Genomic DNA. No translation available.
KF458771 Genomic DNA. No translation available.
AK300881 mRNA. Translation: BAG62523.1.
UniGeneiHs.720023.

3D structure databases

ProteinModelPortaliB4DV11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000379865.

Proteomic databases

PeptideAtlasiB4DV11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000396621; ENSP00000379864; ENSG00000147576.
UCSCiuc064niv.1. human.

Organism-specific databases

HGNCiHGNC:16354. ADHFE1.
OpenTargetsiENSG00000147576.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3857. Eukaryota.
COG1454. LUCA.
GeneTreeiENSGT00390000003849.
HOGENOMiHOG000069907.
HOVERGENiHBG103454.

Gene expression databases

BgeeiENSG00000147576.
ExpressionAtlasiB4DV11. baseline and differential.

Family and domain databases

InterProiIPR001670. ADH_Fe.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DV11_HUMAN
AccessioniPrimary (citable) accession number: B4DV11
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.