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B4DV11

- B4DV11_HUMAN

UniProt

B4DV11 - B4DV11_HUMAN

Protein
Submitted name:

Hydroxyacid-oxoacid transhydrogenase, mitochondrial

Gene

ADHFE1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. metal ion binding Source: InterPro
    2. oxidoreductase activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hydroxyacid-oxoacid transhydrogenase, mitochondrialImported
    Submitted name:
    cDNA FLJ53664, highly similar to Rattus norvegicus alcohol dehydrogenase, iron containing, 1 (Adhfe1), mRNAImported
    Gene namesi
    Name:ADHFE1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:16354. ADHFE1.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000069907.
    HOVERGENiHBG103454.

    Family and domain databases

    InterProiIPR001670. ADH_Fe.
    [Graphical view]
    PfamiPF00465. Fe-ADH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B4DV11-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAAAARARVA YLLRQLQRAA CQCPTHSHTY SQAPGLSPSG KTTDYAFEMA    50
    VSNIRYGAAV TKEVGMDLKN MGAKNVCLMT DKNLSKLPPV QVAMDSLVKN 100
    GIPFTVYDNV RVEPTDSSAN YLRNRE 126
    Length:126
    Mass (Da):13,770
    Last modified:September 23, 2008 - v1
    Checksum:i9AAC8D7F89449762
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009879 Genomic DNA. No translation available.
    KF458771 Genomic DNA. No translation available.
    AK300881 mRNA. Translation: BAG62523.1.
    UniGeneiHs.720023.

    Genome annotation databases

    EnsembliENST00000396621; ENSP00000379864; ENSG00000147576.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009879 Genomic DNA. No translation available.
    KF458771 Genomic DNA. No translation available.
    AK300881 mRNA. Translation: BAG62523.1 .
    UniGenei Hs.720023.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000396621 ; ENSP00000379864 ; ENSG00000147576 .

    Organism-specific databases

    HGNCi HGNC:16354. ADHFE1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000069907.
    HOVERGENi HBG103454.

    Miscellaneous databases

    NextBioi 35475326.

    Family and domain databases

    InterProi IPR001670. ADH_Fe.
    [Graphical view ]
    Pfami PF00465. Fe-ADH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 8."
      Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
      , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
      Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Small intestineImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB4DV11_HUMAN
    AccessioniPrimary (citable) accession number: B4DV11
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 23, 2008
    Last sequence update: September 23, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3