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B4DV01

- B4DV01_HUMAN

UniProt

B4DV01 - B4DV01_HUMAN

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Protein
Submitted name: cDNA FLJ57605, highly similar to Protein kinase C eta type (EC 2.7.11.13)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. calcium-independent protein kinase C activity Source: Ensembl

GO - Biological processi

  1. positive regulation of keratinocyte differentiation Source: Ensembl
  2. positive regulation of macrophage derived foam cell differentiation Source: Ensembl
  3. protein kinase C signaling Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB4DV01.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ57605, highly similar to Protein kinase C eta type (EC 2.7.11.13)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. plasma membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DV01.

Expressioni

Gene expression databases

ArrayExpressiB4DV01.
BgeeiB4DV01.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliB4DV01.
SMRiB4DV01. Positions 1-249.

Family & Domainsi

Sequence similaritiesi

Contains AGC-kinase C-terminal domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG108317.

Family and domain databases

InterProiIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTiSM00133. S_TK_X. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51285. AGC_KINASE_CTER. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DV01-1 [UniParc]FASTAAdd to Basket

« Hide

MEFVNGGDLM FHIQKSRRFD EARARFYAAE IISALMFLHD KGIIYRDLKL    50
DNVLLDHEGH CKLADFGMCK EGICNGVTTA TFCGTPDYIA PEILQEMLYG 100
PAVDWWAMGV LLYEMLCGHA PFEAENEDDL FEAILNDEVV YPTWLHEDAT 150
GILKSFMTKN PTMRLGSLTQ GGEHAILRHP FFKEIDWAQL NHRQIEPPFR 200
PRIKSREDVS NFDPDFIKEE PVLTPIDEGH LPMINQDEFR NFSYVSPELQ 250
P 251
Length:251
Mass (Da):28,899
Last modified:September 23, 2008 - v1
Checksum:i4392FF7B1233747B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK300864 mRNA. Translation: BAG62513.1.
UniGeneiHs.333907.

Genome annotation databases

UCSCiuc010tsb.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK300864 mRNA. Translation: BAG62513.1 .
UniGenei Hs.333907.

3D structure databases

ProteinModelPortali B4DV01.
SMRi B4DV01. Positions 1-249.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi B4DV01.

Proteomic databases

PRIDEi B4DV01.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc010tsb.2. human.

Phylogenomic databases

HOVERGENi HBG108317.

Enzyme and pathway databases

SignaLinki B4DV01.

Miscellaneous databases

NextBioi 35475318.

Gene expression databases

ArrayExpressi B4DV01.
Bgeei B4DV01.

Family and domain databases

InterProi IPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view ]
SMARTi SM00133. S_TK_X. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51285. AGC_KINASE_CTER. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Small intestineImported.

Entry informationi

Entry nameiB4DV01_HUMAN
AccessioniPrimary (citable) accession number: B4DV01
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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