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Protein

Non-specific serine/threonine protein kinase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB4DV01

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DV01
PRIDEiB4DV01

Structurei

3D structure databases

SMRiB4DV01
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 182Protein kinaseInterPro annotationAdd BLAST182
Domaini183 – 251AGC-kinase C-terminalInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG0694 Eukaryota
ENOG410XNPH LUCA
HOVERGENiHBG108317

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

B4DV01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFVNGGDLM FHIQKSRRFD EARARFYAAE IISALMFLHD KGIIYRDLKL
60 70 80 90 100
DNVLLDHEGH CKLADFGMCK EGICNGVTTA TFCGTPDYIA PEILQEMLYG
110 120 130 140 150
PAVDWWAMGV LLYEMLCGHA PFEAENEDDL FEAILNDEVV YPTWLHEDAT
160 170 180 190 200
GILKSFMTKN PTMRLGSLTQ GGEHAILRHP FFKEIDWAQL NHRQIEPPFR
210 220 230 240 250
PRIKSREDVS NFDPDFIKEE PVLTPIDEGH LPMINQDEFR NFSYVSPELQ

P
Length:251
Mass (Da):28,899
Last modified:September 23, 2008 - v1
Checksum:i4392FF7B1233747B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300864 mRNA Translation: BAG62513.1
UniGeneiHs.333907

Similar proteinsi

Entry informationi

Entry nameiB4DV01_HUMAN
AccessioniPrimary (citable) accession number: B4DV01
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.