B4DV01 (B4DV01_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ57605, highly similar to Protein kinase C eta type (EC 2.7.11.13) EMBL BAG62513.1
Organism	Homo sapiens (Human) EMBL BAG62513.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	251 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS017892
Sequence similarities	Contains 1 AGC-kinase C-terminal domain.

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS017892 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS017892 Transferase
Gene Ontology (GO)
Biological_process	positive regulation of keratinocyte differentiation Inferred from electronic annotation. Source: Compara positive regulation of macrophage derived foam cell differentiation Inferred from electronic annotation. Source: Compara protein kinase C signaling cascade Inferred from electronic annotation. Source: Compara
Cellular_component	cytosol Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium-independent protein kinase C activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B4DV01 [UniParc]. Last modified September 23, 2008. Version 1. Checksum: 4392FF7B1233747B	FASTA	251	28,899
	10 20 30 40 50 60 MEFVNGGDLM FHIQKSRRFD EARARFYAAE IISALMFLHD KGIIYRDLKL DNVLLDHEGH 70 80 90 100 110 120 CKLADFGMCK EGICNGVTTA TFCGTPDYIA PEILQEMLYG PAVDWWAMGV LLYEMLCGHA 130 140 150 160 170 180 PFEAENEDDL FEAILNDEVV YPTWLHEDAT GILKSFMTKN PTMRLGSLTQ GGEHAILRHP 190 200 210 220 230 240 FFKEIDWAQL NHRQIEPPFR PRIKSREDVS NFDPDFIKEE PVLTPIDEGH LPMINQDEFR 250 NFSYVSPELQ P

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Small intestine EMBL BAG62513.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK300864 mRNA. Translation: BAG62513.1.
IPI	IPI01009472.
UniGene	Hs.333907.
3D structure databases
ProteinModelPortal	B4DV01.
SMR	B4DV01. Positions 1-249.
ModBase	Search...
Protein-protein interaction databases
STRING	B4DV01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc010tsb.2. human.
Phylogenomic databases
HOVERGEN	HBG108317.
Gene expression databases
ArrayExpress	B4DV01.
Bgee	B4DV01.
Family and domain databases
InterPro	IPR000961. AGC-kinase_C. IPR011009. Kinase-like_dom. IPR017892. Pkinase_C. IPR000719. Prot_kinase_cat_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. PF00433. Pkinase_C. 1 hit. [Graphical view]
SMART	SM00133. S_TK_X. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS51285. AGC_KINASE_CTER. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	B4DV01.
NextBio	35475318.

Entry information

Entry name

B4DV01_HUMAN

Accession

Primary (citable) accession number: B4DV01

Entry history

Integrated into UniProtKB/TrEMBL:	September 23, 2008
Last sequence update:	September 23, 2008
Last modified:	April 3, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.