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Protein

T-complex protein 1 subunit gamma

Gene

CCT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit gammaUniRule annotation
Gene namesi
Name:CCT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000163468.14
HGNCiHGNC:1616 CCT3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163468

PTM / Processingi

Proteomic databases

MaxQBiB4DUR8
PeptideAtlasiB4DUR8

Expressioni

Gene expression databases

BgeeiENSG00000163468

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiB4DUR8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0364 Eukaryota
COG0459 LUCA
GeneTreeiENSGT00570000079224
HOVERGENiHBG104982

Family and domain databases

CDDicd03337 TCP1_gamma, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR012719 Chap_CCT_gamma
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PANTHERiPTHR11353 PTHR11353, 1 hit
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02344 chap_CCT_gamma, 1 hit
PROSITEiView protein in PROSITE
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

B4DUR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKMLLDPMG GIVMTNDGNA ILREIQVQHP AAKSMIEISR TQDEEVGDGT
60 70 80 90 100
TSVIILAGEM LSVAEHFLEQ QMHPTVVISA YRKALDDMIS TLKKISIPVD
110 120 130 140 150
ISDSDMMLNI INSSITTKAI SRWSSLACNI ALDAVKMVQF EENGRKEIDI
160 170 180 190 200
KKYARVEKIP GGIIEDSCVL RGVMINKDVT HPRMRRYIKN PRIVLLDSSL
210 220 230 240 250
EYKKGESQTD IEITREEDFT RILQMEEEYI QQLCEDIIQL KPDVVITEKG
260 270 280 290 300
ISDLAQHYLM RANITAIRRV RKTDNNRIAR ACGARIVSRP EELREDDVGT
310 320 330 340 350
GAGLLEIKKI GDEYFTFITD CKDPKACTIL LRGASKEILS EVERNLQDAM
360 370 380 390 400
QVCRNVLLDP QLVPGGGASE MAVAHALTEK SKAMTGVEQW PYRAVAQALE
410 420 430 440 450
VIPRTLIQNC GASTIRLLTS LRAKHTQENC ETWGVNGETG TLVDMKELGI
460 470 480 490 500
WEPLAVKLQT YKTAVETAVL LLRIDDIVSG HKKKGDDQSR QGGAPDAGQE
Length:500
Mass (Da):55,674
Last modified:September 23, 2008 - v1
Checksum:i5964554B4BE215E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589685 Genomic DNA No translation available.
KF455038 Genomic DNA No translation available.
AK300765 mRNA Translation: BAG62430.1
AK315923 mRNA Translation: BAH14294.1
AK316387 mRNA Translation: BAH14758.1
UniGeneiHs.491494

Genome annotation databases

EnsembliENST00000472765; ENSP00000431543; ENSG00000163468
UCSCiuc057lye.1 human

Similar proteinsi

Entry informationi

Entry nameiB4DUR8_HUMAN
AccessioniPrimary (citable) accession number: B4DUR8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: April 25, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health