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Protein

T-complex protein 1 subunit gamma

Gene

CCT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit gammaUniRule annotation
Gene namesi
Name:CCT3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000163468.14.
HGNCiHGNC:1616. CCT3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163468.

PTM / Processingi

Proteomic databases

MaxQBiB4DUR8.

Expressioni

Gene expression databases

BgeeiENSG00000163468.
ExpressionAtlasiB4DUR8. baseline and differential.

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0364. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00570000079224.
HOVERGENiHBG104982.

Family and domain databases

CDDicd03337. TCP1_gamma. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
InterProiView protein in InterPro
IPR012719. Chap_CCT_gamma.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PANTHERiPTHR11353:SF142. PTHR11353:SF142. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02344. chap_CCT_gamma. 1 hit.
PROSITEiView protein in PROSITE
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.

Sequencei

Sequence statusi: Complete.

B4DUR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKMLLDPMG GIVMTNDGNA ILREIQVQHP AAKSMIEISR TQDEEVGDGT
60 70 80 90 100
TSVIILAGEM LSVAEHFLEQ QMHPTVVISA YRKALDDMIS TLKKISIPVD
110 120 130 140 150
ISDSDMMLNI INSSITTKAI SRWSSLACNI ALDAVKMVQF EENGRKEIDI
160 170 180 190 200
KKYARVEKIP GGIIEDSCVL RGVMINKDVT HPRMRRYIKN PRIVLLDSSL
210 220 230 240 250
EYKKGESQTD IEITREEDFT RILQMEEEYI QQLCEDIIQL KPDVVITEKG
260 270 280 290 300
ISDLAQHYLM RANITAIRRV RKTDNNRIAR ACGARIVSRP EELREDDVGT
310 320 330 340 350
GAGLLEIKKI GDEYFTFITD CKDPKACTIL LRGASKEILS EVERNLQDAM
360 370 380 390 400
QVCRNVLLDP QLVPGGGASE MAVAHALTEK SKAMTGVEQW PYRAVAQALE
410 420 430 440 450
VIPRTLIQNC GASTIRLLTS LRAKHTQENC ETWGVNGETG TLVDMKELGI
460 470 480 490 500
WEPLAVKLQT YKTAVETAVL LLRIDDIVSG HKKKGDDQSR QGGAPDAGQE
Length:500
Mass (Da):55,674
Last modified:September 23, 2008 - v1
Checksum:i5964554B4BE215E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589685 Genomic DNA. No translation available.
KF455038 Genomic DNA. No translation available.
AK300765 mRNA. Translation: BAG62430.1.
AK315923 mRNA. Translation: BAH14294.1.
AK316387 mRNA. Translation: BAH14758.1.
UniGeneiHs.491494.

Genome annotation databases

EnsembliENST00000472765; ENSP00000431543; ENSG00000163468.
UCSCiuc057lye.1. human.

Similar proteinsi

Entry informationi

Entry nameiB4DUR8_HUMAN
AccessioniPrimary (citable) accession number: B4DUR8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: September 27, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported