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B4DUM2

- B4DUM2_HUMAN

UniProt

B4DUM2 - B4DUM2_HUMAN

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Protein
Submitted name:

cDNA FLJ53891, highly similar to Adenylosuccinate lyase (EC 4.3.2.2)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: Ensembl
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: Ensembl

GO - Biological processi

  1. aerobic respiration Source: Ensembl
  2. AMP biosynthetic process Source: Ensembl
  3. protein tetramerization Source: Ensembl
  4. response to hypoxia Source: Ensembl
  5. response to muscle activity Source: Ensembl
  6. response to nutrient Source: Ensembl
  7. response to starvation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53891, highly similar to Adenylosuccinate lyase (EC 4.3.2.2)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Ensembl
  2. mitochondrion Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB4DUM2.

Expressioni

Gene expression databases

ArrayExpressiB4DUM2.
BgeeiB4DUM2.

Structurei

3D structure databases

ProteinModelPortaliB4DUM2.
SMRiB4DUM2. Positions 1-294.

Family & Domainsi

Family and domain databases

InterProiIPR019468. AdenyloSucc_lyase_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SMARTiSM00998. ADSL_C. 1 hit.
[Graphical view]
SUPFAMiSSF48557. SSF48557. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DUM2-1 [UniParc]FASTAAdd to Basket

« Hide

MDLQNLKRVR DDLRFRGVKG TTGTQASFLQ LFEGDDHKVE QLDKMVTEKA    50
GFKRAFIITG QTYTRKVDIE VLSVLASLGA SVHKICTDIR LLANLKEMEE 100
PFEKQQIGSS AMPYKRNPMR SERCCSLARH LMTLVMDPLQ TASVQWFERT 150
LDDSANRRIC LAEAFLTADT ILNTLQNISE GLVVYPKVIE RRIRQELPFM 200
ATENIIMAMV KAGGSRQDCH EKIRVLSQQA ASVVKQEGGD NDLIERIQVD 250
AYFSPIHSQL DHLLDPSSFT GRASQQVQRF LEEEVYPLLK PYESVMKVKA 300
ELCL 304
Length:304
Mass (Da):34,555
Last modified:September 23, 2008 - v1
Checksum:iEB0C042A7A79A624
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK300705 mRNA. Translation: BAG62384.1.
UniGeneiHs.75527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK300705 mRNA. Translation: BAG62384.1 .
UniGenei Hs.75527.

3D structure databases

ProteinModelPortali B4DUM2.
SMRi B4DUM2. Positions 1-294.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B4DUM2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

NextBioi 35475227.

Gene expression databases

ArrayExpressi B4DUM2.
Bgeei B4DUM2.

Family and domain databases

InterProi IPR019468. AdenyloSucc_lyase_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SMARTi SM00998. ADSL_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48557. SSF48557. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Skeletal muscleImported.

Entry informationi

Entry nameiB4DUM2_HUMAN
AccessioniPrimary (citable) accession number: B4DUM2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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