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Protein
Submitted name:

cDNA FLJ60161, moderately similar to Gamma-secretase subunit APH-1A

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ60161, moderately similar to Gamma-secretase subunit APH-1AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei60 – 7819HelicalSequence analysisAdd
BLAST
Transmembranei98 – 12326HelicalSequence analysisAdd
BLAST
Transmembranei130 – 15223HelicalSequence analysisAdd
BLAST
Transmembranei158 – 17922HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB4DUG7.

Expressioni

Gene expression databases

GenevisibleiB4DUG7. HS.

Structurei

3D structure databases

ProteinModelPortaliB4DUG7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000007541.
HOVERGENiHBG050541.

Family and domain databases

InterProiIPR009294. Aph-1.
[Graphical view]
PANTHERiPTHR12889. PTHR12889. 1 hit.
PfamiPF06105. Aph-1. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DUG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAAVFFGCT FVAFGPAFAL FLITVAGDPL RVIILVAGKA DEGLASLSED
60 70 80 90 100
GRSPISIRQM AYVSGLSFGI ISGVFSVINI LADALGPGVV GIHGDSPYYF
110 120 130 140 150
LTSAFLTAAI ILLHTFWGVV FFDACERRRY WALGLVVGSH LLTSGLTFLN
160 170 180 190
PWYEASLLPI YAVTVSMGLW AFITAGGSLR SIQRSLLCKD
Length:190
Mass (Da):20,250
Last modified:September 23, 2008 - v1
Checksum:i7C8F464511739F65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300640 mRNA. Translation: BAG62329.1.
RefSeqiNP_001230700.1. NM_001243771.1.
UniGeneiHs.108408.
Hs.735911.

Genome annotation databases

GeneIDi51107.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300640 mRNA. Translation: BAG62329.1.
RefSeqiNP_001230700.1. NM_001243771.1.
UniGeneiHs.108408.
Hs.735911.

3D structure databases

ProteinModelPortaliB4DUG7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB4DUG7.

Protocols and materials databases

DNASUi51107.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi51107.

Organism-specific databases

CTDi51107.

Phylogenomic databases

HOGENOMiHOG000007541.
HOVERGENiHBG050541.

Miscellaneous databases

GenomeRNAii51107.

Gene expression databases

GenevisibleiB4DUG7. HS.

Family and domain databases

InterProiIPR009294. Aph-1.
[Graphical view]
PANTHERiPTHR12889. PTHR12889. 1 hit.
PfamiPF06105. Aph-1. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DUG7_HUMAN
AccessioniPrimary (citable) accession number: B4DUG7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: July 6, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.