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Protein
Submitted name:

cDNA FLJ54483, highly similar to Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

SignaLinkiB4DUC2.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ54483, highly similar to Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiB4DUC2.
PeptideAtlasiB4DUC2.
PRIDEiB4DUC2.

Interactioni

Protein-protein interaction databases

IntActiB4DUC2. 1 interactor.
STRINGi9606.ENSP00000275780.

Structurei

3D structure databases

ProteinModelPortaliB4DUC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini408 – 687Protein kinaseInterPro annotationAdd BLAST280

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili286 – 313Sequence analysisAdd BLAST28
Coiled coili359 – 393Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1151. Eukaryota.
ENOG410Y3FX. LUCA.
HOVERGENiHBG007938.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR027086. TLK2.
[Graphical view]
PANTHERiPTHR22974:SF20. PTHR22974:SF20. 2 hits.
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B4DUC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEELHSLDP RRQELLEARF TGVGVSKGPL NSESSNQSLC SVGSLSDKEV
60 70 80 90 100
ETPEKKQNDQ RNRKRKAEPY ETSQGKDTPR GHKISDYFER RVEQPLYGLD
110 120 130 140 150
GSAAKEATEE QSALPTLMSV MLAKPRLDTE QLAQRGAGLC FTFVSAQQNS
160 170 180 190 200
PSSTGSGNTE HSCSSQKQIS IQHRQTQSDL IIEKISALEN SKNSDLEKKE
210 220 230 240 250
GRIDDLLRAN CDLRRQIDEQ QKMLEKYKER LNRCVTMSKK LLIEKSKQEK
260 270 280 290 300
MACRDKSMQD RLRLGHFTTV RHGASFTEQW TDGYAFQNLI KQQERINSQR
310 320 330 340 350
EEIERQRKML AKRKPPAMGQ APPATNEQKQ RKSKTNGAEN ETLTLAEYHE
360 370 380 390 400
QEEIFKLRLG HLKKEEAEIQ AELERLERVR NLHIRELKRI HNEDNSQFKD
410 420 430 440 450
HPTLNDRYLL LHLLGRGGFS EVYKAFDLTE QRYVAVKIHQ LNKNWRDEKK
460 470 480 490 500
ENYHKHACRE YRIHKELDHP RIVKLYDYFS LDTDSFCTVL EYCEGNDLDF
510 520 530 540 550
YLKQHKLMSE KEARSIIMQI VNALKYLNEI KPPIIHYDLK PGNILLVNGT
560 570 580 590 600
ACGEIKITDF GLSKIMDDDS YNSVDGMELT SQGAGTYWYL PPECFVVGKE
610 620 630 640 650
PPKISNKVDV WSVGVIFYQC LYGRKPFGHN QSQQDILQEN TILKATEVQF
660 670 680 690 700
PPKPVVTPEA KAFIRRCLAY RKEDRIDVQQ LACDPYLLPH IRKSVSTSSP
710
AGAAIASTSG ASNNSSSN
Length:718
Mass (Da):82,418
Last modified:September 23, 2008 - v1
Checksum:iCC92364657BEFD2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300586 mRNA. Translation: BAG62284.1.
RefSeqiNP_001271292.1. NM_001284363.1.
UniGeneiHs.445078.

Genome annotation databases

GeneIDi11011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300586 mRNA. Translation: BAG62284.1.
RefSeqiNP_001271292.1. NM_001284363.1.
UniGeneiHs.445078.

3D structure databases

ProteinModelPortaliB4DUC2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB4DUC2. 1 interactor.
STRINGi9606.ENSP00000275780.

Proteomic databases

PaxDbiB4DUC2.
PeptideAtlasiB4DUC2.
PRIDEiB4DUC2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11011.

Organism-specific databases

CTDi11011.

Phylogenomic databases

eggNOGiKOG1151. Eukaryota.
ENOG410Y3FX. LUCA.
HOVERGENiHBG007938.

Enzyme and pathway databases

SignaLinkiB4DUC2.

Miscellaneous databases

GenomeRNAii11011.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR027086. TLK2.
[Graphical view]
PANTHERiPTHR22974:SF20. PTHR22974:SF20. 2 hits.
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB4DUC2_HUMAN
AccessioniPrimary (citable) accession number: B4DUC2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: October 5, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.